research Intracellular protons accelerate aging and switch on aging hallmarks in mice
Acid inside cells speeds up aging and turns on aging signs in mice.
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30 / 1000+ resultsresearch Mechanisms of proton inhibition and sensitization of the cation channel TRPV3
Acid can block TRPV3 from outside the cell but boost its function from inside.
research Activation of temperature-sensitive Ca2+-permeable TRPV3 channels by natural ï¡-hydroxyl acids causes exfoliation for skin-resurfacing
Natural α-hydroxyl acids cause skin exfoliation by activating TRPV3 channels.
research Melatonin membrane receptors in peripheral tissues: Distribution and functions
Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
research Biallelic HEPHL1 variants impair ferroxidase activity and cause an abnormal hair phenotype
Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.
research The metabolic syndrome- associated small G protein ARL15 plays a role in adipocyte differentiation and adiponectin secretion
ARL15 is important for fat cell development and the release of the hormone adiponectin.
research The Role of the Slc39a Family of Zinc Transporters in Zinc Homeostasis in Skin
Certain zinc transporters are essential for healthy skin and managing zinc in the body could help treat skin problems.
research Novel anti-aging gene NM_026333 contributes to proton-induced aging via NCX1-pathway
The gene NM_026333 slows down aging by affecting the NCX1 pathway and could be targeted for anti-aging treatments.
research Heterozygous Arrhythmogenic Cardiomyopathy-desmoplakin Mutation Carriers Exhibit a Subclinical Cutaneous Phenotype with Cell Membrane Disruption and Lack of Intercellular Adhesion
Carriers of a specific gene mutation have subtle skin changes without visible symptoms.
research Cell fate decisions: emerging roles for metabolic signals and cell morphology
Metabolic signals and cell shape influence how cells develop and change.
research The optimal holding solution and temperature for hair follicle grafts
Best solution for storing hair grafts is saline with ATP at 4 degrees Celsius, but no definitive best method was confirmed.
research Plasma Dermatology: Skin Therapy Using Cold Atmospheric Plasma
Cold atmospheric plasma is a promising and safe treatment for various skin conditions.
research Design and Clinical Assessment of a Non-Invasive, Low-Power Laser Irradiation System for Post-Hysterectomy Genitourinary Rehabilitation in Cervical Cancer Patients
The laser system can safely improve recovery and quality of life for cervical cancer patients after surgery.
research Histopathological and Ultrastructural Study of Ectodermal Dysplasia/Skin Fragility Syndrome
The study concluded that PKP1 is essential for skin integrity and hair growth, and its dysfunction causes the symptoms of ectodermal dysplasia/skin fragility syndrome.
research Chitosan stimulates root hair callose deposition and inhibits root hair growth
Chitosan slows root hair growth and causes a buildup of callose at low concentrations, but at high concentrations, it only inhibits growth without callose buildup.
research Dysfunction of keratinocyte adhesion
Keratinocyte adhesion problems can cause skin and hair disorders.
research Unlocking the therapeutic potential of TRPV3: Insights into thermosensation, channel modulation, and skin homeostasis involving TRPV3
TRPV3 is important for skin health and could be a target for treating skin diseases.
research Editor's evaluation: Plant Trans-Golgi Network/Early Endosome pH regulation requires Cation Chloride Cotransporter (CCC1)
CCC1 is crucial for pH balance in plant cells, affecting growth and stress tolerance.
research Unlocking the Power of Light on the Skin: A Comprehensive Review on Photobiomodulation
Light-based treatment, Photobiomodulation, shows promise for non-invasive skin therapy with few side effects.
research Improving the treatment of bacterial infections caused by multidrug-resistant bacteria through drug repositioning
Using existing drugs for new purposes can effectively treat infections resistant to multiple antibiotics.
research Barrett's esophagus as a premalignant condition; medical and surgical therapeutic management
Early detection and personalized treatment are crucial to prevent Barrett's esophagus from becoming cancer.
research Bilateral Eyelid Pseudoptosis From Lipogranulomas of the Preaponeurotic Fat Pads
Surgical removal of abnormal fat pads fixed the woman's eyelid issue caused by likely silicone injections.
research The Application Progress of Tumor Microenvironment-Responsive Drug Carriers in Precision Chemotherapy
Tumor-targeted drug carriers can improve chemotherapy precision and reduce side effects.
research Polymeric nanoparticles‐based topical delivery systems for the treatment of dermatological diseases
Polymeric nanoparticles show promise for treating skin diseases.
research Spatiotemporal control of CRISPR/Cas9 gene editing
The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.
research Scalp cooling in the prevention of anthracycline-induced alopecia
Scalp cooling prevented hair loss in half of the patients, despite significant side effects.
research Inherited Disorders of the Hair
The document explains the genetic causes and characteristics of inherited hair disorders.
research Hair loss after covid 19 - case series
COVID-19 can cause different types of hair loss, with telogen effluvium being the most common.
research How Does pH Fit in with Oscillating Polar Growth?
pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.
research Role of Plant Growth-Promoting Rhizobacteria (PGPR) as BioFertilizers in Stabilizing Agricultural Ecosystems
Using PGPR as biofertilizers can improve soil health and plant growth while reducing reliance on synthetic fertilizers.