research Bone vs. fat: Embryonic origin of progenitors determines response to androgen in adipocytes and osteoblasts
Androgens affect bone and fat cell development differently based on the cells' embryonic origin.
Search
for
Sort by
Research
180-210 / 1000+ results research Steroidogenesis inhibitors alter but do not eliminate androgen synthesis mechanisms during progression to castration-resistance in LNCaP prostate xenografts
Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.
research Studies on neurosteroids XXIV. Determination of neuroactive androgens, androsterone and 5α‐androstane‐3α,17β‐diol, in rat brain and serum using liquid chromatography–tandem mass spectrometry
The methods accurately measured brain androgens, showing most 5α-androstane-3α,17β-diol comes from outside the brain, while androsterone is both transported and made in the brain.
research Preparation of3H-labelled testosterone metabolites
The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.
research Altered brain and pituitary androgen metabolism by prenatal, perinatal or pre- and postnatal finasteride, flutamide or dihydrotestosterone treatment in juvenile male rats
Treatment during development affects hormone balance and sexual behavior in male rats.
research Androgen‐induced neurite outgrowth is mediated by neuritin in motor neurones
Androgens help motor neurons grow by increasing neuritin.
research Metabolism of androgens by isolated human beard hair follicles
Human beard hair follicles change testosterone into other related hormones, but don't much change androstenedione into testosterone.
research Androgen Receptor Ligands: Agonists and Antagonists
Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.
research In vitro [7-3H]-testosterone metabolism by the rat ventral prostate—Effect of some exogenous compounds
research Genetic regulation of the androgen receptor—A study of testicular feminization in the mouse
The study concludes that a genetic mutation in TFM mice leads to reduced androgen receptor activity, affecting the body's response to male hormones.
research 1406 DETECTION OF MEMBRANE ANDROGEN-BINDING SITE IN LIVING RAT PROSTATE AND EVALUATION OF ITS ROLE IN PROSTATE BLOOD FLOW REGULATION
The research found that androgens help control blood flow in the rat prostate through a specific binding site.
research Testosterone metabolites differentially maintain adult morphology in a sexually dimorphic neuromuscular system
Androgens are essential for maintaining adult neuromuscular structure.
research Epitestosterone—an endogenous antiandrogen?
Epitestosterone may act as a weak antiandrogen and can inhibit an enzyme involved in testosterone metabolism.
research Regional Variation in Androgen Receptor Expression and Biomechanical Properties May Contribute to Cryptorchidism Susceptibility in the LE/orl Rat
Differences in androgen receptor expression and tissue properties may lead to higher cryptorchidism risk in certain rats.
research Androgen action on human skin – from basic research to clinical significance
Hormones like testosterone affect skin functions and can cause skin issues when in excess; treatments to manage these effects are only somewhat effective.
research Serum androgen bioactivity is low in children with premature adrenarche
research Androgens and the hair follicle. Cultured human dermal papilla cells as a model system.
research Androgens trigger different growth responses in genetically identical human hair follicles in organ culture that reflect their epigenetic diversity in life
Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.
research Studies of androgen metabolism and action in cultured hair and skin cells
Androgens don't directly affect hair cell growth or protein production.
research Organizational Effects of Estrogens and Androgens on Estrogen and Androgen Receptor Expression in Pituitary and Adrenal Glands in Adult Male and Female Rats
Early hormones shape sex-specific differences in rat glands.
research 1 Androgens
Testosterone is made by Leydig cells, is active when not bound to proteins, and works by binding to receptors in muscles and other tissues.
research Discovery of Nonsteroidal Androgens
Scientists found new nonsteroidal compounds that can act like natural male hormones and might help treat male fertility and hormone issues.
research Androgens
Male hormones and their interactions are crucial for male sexual development and characteristics.
research Systematic analyses of murine masculinization processes based on genital sex differentiation parameters
DHT is crucial for urethral formation, and its disruption can affect masculinization and lead to hypospadias.
research Non-canonical dimerization of the androgen receptor and other nuclear receptors: implications for human disease
Mutations in certain receptors can cause diseases and offer new treatment options.
research Metabolism of androgens by isolated human hair follicles
Beard hair follicles convert testosterone to 5α-dihydrotestosterone most intensively.
research Disruption of androgen metabolism, regulation and effects : involvement of steroidogenic enzymes
Anabolic steroids and inflammation can disrupt androgen metabolism, potentially causing health issues.
research Immunolocalization of androgen receptor in the epididymis of rats with dihydrotestosterone deficiency.
Finasteride changes androgen receptor location in rat epididymis without altering tissue structure.
research Androgen regulations of cellular events involve in bone perfusion
research Androgenic effect of testosterone and some of its metabolites in relation to their biotransformation in the skin.
Testosterone and some of its forms can strongly stimulate oil gland growth in skin.