Sensory neuron and Merkel-cell changes in the skin happen independently during normal skin maintenance.
128 citations
,
March 1996 in “Journal of Investigative Dermatology” 20 citations
,
January 2002 in “Laboratory Animals” Mutations in the hairless gene cause hair loss and skin cysts in rhesus macaques.
96 citations
,
December 1995 in “Journal of Investigative Dermatology” 8 citations
,
August 1986 in “Journal of Investigative Dermatology” 44 citations
,
January 2018 in “The International Journal of Developmental Biology” Stem cells in the skin help with healing and can also lead to cancer.
28 citations
,
July 2007 in “Development” TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
April 2012 in “Development” Rac1 is crucial for normal hair structure and pigmentation.
18 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
13 citations
,
June 2020 in “Scientific reports” Melatonin stimulates the skin components of ram's scrotum during their non-breeding season.
January 2005 in “Journal of Shandong Univenity” Epidermal stem cells are in hair follicle bulge regions, and isolation and culture methods are effective.
3 citations
,
October 2019 in “Pharmaceutics” New technique implants pigment in scalp with less pain and damage.
9 citations
,
July 2014 in “PubMed” Different S100 proteins have specific roles in various parts of the hair follicle.
174 citations
,
November 2016 in “Cell stem cell” Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.
January 2011 in “Yearbook of Dermatology and Dermatologic Surgery” Moles on the scalp are more common in people with more body moles and atypical moles, but not linked to balding.
13 citations
,
May 2017 in “Current Protocols in Stem Cell Biology” A method was developed to isolate and study hair follicle stem cells from mouse skin.
119 citations
,
January 2000 in “British Journal of Dermatology” Different parts of the nail express different keratins, showing unique patterns of differentiation.
14 citations
,
February 2020 in “Scientific reports” Telocytes in the scalp may help with skin regeneration and maintenance.
10 citations
,
August 2023 in “Animals” SLC45A2 and GPNMB genes help control chicken feather color by promoting melanin.
October 2023 in “Oncotarget” Apoptotic cells help cause hair follicle cell death during regression.
11 citations
,
February 2018 in “Archives of Pharmacal Research” Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.
1 citations
,
January 1989 Four antibodies were developed to help study hair follicle cell differentiation.
November 2013 in “Elsevier eBooks” Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
5 citations
,
October 2024 in “Molecules and Cells” Epidermal stem cells work with the skin's environment to heal wounds effectively.
April 2018 in “Journal of Investigative Dermatology” Researchers found that the Leptin receptor is a consistent marker for hair follicle dermal cells, which may help future hair research.
48 citations
,
March 2003 in “International Journal of Cancer” DMBT1 and galectin-3 may help suppress epithelial skin cancer.
July 2019 in “Cancer Research” Bone marrow and hair follicle cells help form skin tumors, suggesting new treatment targets.
February 2022 in “Cosmetic Dermatology” Healthy skin prevents water loss and protects against threats.
January 2013 in “วารสารเภสัชศาสตร์อีสาน (Isan Journal of Pharmaceutical Sciences, IJPS)” Safflower extract increases melanin production in certain skin cells without harming them.
58 citations
,
February 2016 in “Scientific reports” Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.