research Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
Adding a second method to PROTACs could improve cancer treatment.
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570-600 / 1000+ results research Developmental and evolutionary comparative analysis of a regulatory landscape in mouse and chicken
Gene regulation evolved differently in mouse and chicken skin, but remained stable in their trunks.
research Identification of key genes and signaling pathways related to Hetian sheep wool density by RNA-seq technology
Certain genes and pathways are linked to the production of finer and denser wool in Hetian sheep.
research Protease-Activated Receptor-1 (Thrombin Receptor) Is Expressed in Mesenchymal Portions of Human Hair Follicle
PAR-1 may play a role in hair growth regulation in human hair follicles.
research Coloration in Equine: Overview of Candidate Genes Associated with Coat Color Phenotypes
Genes like MC1R, TYR, MITF, ASIP, and KIT determine horse and donkey coat colors and affect breeding and health.
research Biological Potential and Therapeutic Effectiveness of Hinokiflavone in Medicine: The Effective Components of Herbal Medicines for Treatment of Cancers and Associated Complications
Hinokiflavone may help treat cancers and other health issues.
research De novo filament formation by human hair keratins K85 and K35 follows a filament development pattern distinct from cytokeratin filament networks
Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.
research Peptide-Based PROTACs: Transitioning from Static Paradigm to a Dynamic Landscape within Targeted Protein Degradation
Peptide-based PROTACs show promise in targeting hard-to-treat proteins, especially for cancer therapy.
research Effective Penetration of the Oxidized Keratin‐Rebonding Materials Into Hair Shafts Based on Charge Conversion
Charge-conversion chemistry improves hair-rebonding by enhancing penetration and strength.
research Potential of Natural Products in Hangeshashinto Water Extract on the Direct Suppression of Stomatitis Induced by Intra-/Extracellular Advanced Glycation End-Products
Hangeshashinto's natural products may help treat stomatitis by reducing inflammation and cytotoxicity.
research Thiohydrazides in the Synthesis of Functionalized Extranuclear Heterosteroids
New steroid derivatives show promise as anticancer agents, even against resistant cells.
research Discrete Nanoscale Distribution of Hair Lipids Fails to Provide Humidity Resistance
Hair lipids do not protect against humidity.
research In vivo formation steps of the hard α-keratin intermediate filament along a hair follicle: Evidence for structural polymorphism
Hair follicles form hard α-keratin filaments in four steps, showing structural differences.
research Template‐directed self‐assembly and growth of insulin amyloid fibrils
A new method speeds up insulin amyloid fibril growth, useful for studying diseases.
research Structural investigation on damaged hair keratin treated with α,β-unsaturated Michael acceptors used as repairing agents
Treatments improved hair surface and scale structure but didn't increase certain bonds in the hair cortex.
research QSAR Analysis of a Series of Hydantoin‐based Androgen Receptor Modulators and Corresponding Binding Affinities
Researchers developed reliable models to predict how well certain compounds bind to androgen receptors, emphasizing the importance of atomic electronegativity.
research O potencial de cicatrização do hidrogel Qui/HPMC/Ins
research Use of rotary echoes in 2 H
A new method accurately measures molecular movement without complex modeling.
research Hydrolyzed Hair Keratin
research Evolution of hard proteins in the sauropsid integument in relation to the cornification of skin derivatives in amniotes
Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.
research Characterization of Human KAP24.1, A Cuticular Hair Keratin-Associated Protein with Unusual Amino-Acid Composition and Repeat Structure
Scientists discovered a unique hair protein, KAP24.1, with a special structure, found only in the upper part of hair cuticles.
research Atypical formations of gintonin lysophosphatidic acids as new materials and their beneficial effects on degenerative diseases
New ginseng compounds may help treat degenerative diseases.
research Hair-Hair Contact Dynamics and Interactions Studied with Atomic Force Microscopy
Hair movement can indicate hair quality and health.
research Transglutaminase-mediated cross-linking in mammalian epidermis
research A New Permanent Straightening Process of Human Hair Using the Water Set
The new hair straightening method keeps hair straight permanently by using specific creams and heat.
research The Effect of Hydration on the Mechanical Behaviour of Hair
research Nucleation and growth of macrofibrils in trichocyte (hard-α) keratins
Sheet formation is key to macrofibril structure differences in wool.
research A Ca 2+ /calmodulin-dependent protein kinase required for symbiotic nodule development: Gene identification by transcript-based cloning
The DMI3 gene is essential for nodule development and symbiosis in certain plants.
research Cell death by cornification
Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
research Regulation of adult stem cell quiescence and its functions in the maintenance of tissue integrity
Quiescent adult stem cells are crucial for tissue repair and maintenance.