April 2020 in “Journal of the Endocrine Society” A woman's high testosterone and related symptoms were caused by overactive cells in her ovaries.
1 citations
,
November 2002 in “Endocrine practice” The patient's high testosterone was reduced by a medication that suppresses gonadotropin.
3 citations
,
October 1995 in “Southern Medical Journal” Finasteride may cause breast enlargement, low testosterone a risk factor.
1 citations
,
May 2013 in “Journal of the Egyptian Women's Dermatologic Society (Print)” PSA could be a marker for hyperandrogenism in women, but more research is needed.
7 citations
,
January 2021 in “The Journal of Sexual Medicine” Testosterone with dutasteride improves muscle strength and body composition in trans men.
122 citations
,
November 2014 in “BMC Medicine” Oral testosterone therapy raises heart risk more than other methods.
49 citations
,
August 1996 in “The Journal of Clinical Endocrinology and Metabolism” The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.
January 2005 in “Journal of Investigative Medicine” Testosterone boosts physical performance, grip strength, and lean body mass in older men with low testosterone.
January 2020 in “Journal of Men s Health” The combination treatment reduced prostate size and improved testosterone deficiency symptoms but was less effective for sexual function.
1 citations
,
November 2023 in “American journal of clinical pathology” Transgender men on testosterone therapy need ongoing gynecologic care due to potential cancer risks.
April 2018 in “The Journal of Urology” Phosphodiesterase inhibitors like tadalafil can reduce cell growth in BPH caused by CD8+ T cells in low androgen conditions.
72 citations
,
October 1998 in “Baillière's clinical endocrinology and metabolism” Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.
Testosterone works in different ways, including direct interaction with its receptor, conversion to other hormones for specific effects on genitalia, hair, bones, and muscle, and changes in body fat and sexual function when low.
November 2023 in “JAAD case reports” Exogenous testosterone use may be linked to developing hidradenitis suppurativa.
4 citations
,
May 2013 in “Canadian Urological Association Journal” Finasteride reduces prostate cancer risk by 30% without affecting Gleason scores.
23 citations
,
July 2015 in “The Journal of Membrane Biology” Testosterone increases certain proteins in the uterus, reducing fluid volume.
57 citations
,
August 2018 in “British Journal of Dermatology” Testosterone therapy in transgender men can cause acne.
May 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” Testosterone significantly affects urination differences between male and female mice.
5 citations
,
September 2011 in “Andrologia” Finasteride use may be linked to rare testicular tumor, but more research needed.
January 2005 in “Journal of Investigative Medicine” Testosterone therapy improves strength and body composition in older men with low testosterone.
July 2012 in “The Journal of Urology” Testosterone increases muscle mass regardless of DHT conversion blocking.
January 2023 in “International Journal of Clinical and Medical Education Research” Correct testosterone levels for age to treat prostate cancer, using low dose treatments as necessary.
January 2025 in “International Journal Of Scientific Advances” Topical testosterone can cause acne-like skin changes.
11 citations
,
September 2020 in “OncoTargets and Therapy” Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.
March 2023 in “Archives of Physical Medicine and Rehabilitation” Testosterone and finasteride improve body composition in men with spinal cord injury.
October 2006 in “Urology” Combination therapy with Finasteride is more effective than alpha-blocker alone for BPH symptoms in small prostate volume.
March 2023 in “Archives of Physical Medicine and Rehabilitation” Testosterone and finasteride improve muscle strength and size after spinal cord injury.