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Topical minoxidil helps transgender individuals assigned female at birth grow more facial hair.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Testosterone raises blood pressure and changes kidney protein levels.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Ovarian thecomas can cause virilization in postmenopausal women and are treated with surgery.

ADT for prostate cancer may harm the heart, but GnRH antagonists might be safer.

The document concludes that more inclusive research involving the transgender community is needed, especially on the neovaginal microbiome of trans women.

Topical GT20029 effectively promotes hair regrowth and is well-tolerated.

Formalin-induced pain increases testosterone breakdown in the rat brain and spinal cord.

Dutasteride effectively increases hair density in women with hair loss.

Topical zinc-thymulin is safe and effective for treating male pattern baldness.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Finasteride can help induce ovulation and lead to a healthy birth in some women.

A rare ovarian tumor caused high testosterone and excess hair in a woman, which was resolved after tumor removal.

Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.

Salivary testosterone is a better measure for hirsutism than serum testosterone.

Alopecia in transgender individuals on hormone therapy can worsen emotional distress and affect self-esteem.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

DHT deficiency in rats reduces sperm content and affects testis structure over time.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

Clascoterone may be an effective topical treatment for hair loss.

A woman got male pattern baldness from touching her husband's testosterone gel.

More research is needed to understand how testosterone is maintained in adult males.

Lower testosterone levels may increase heart failure risk in older men.

Cyproterone acetate is effective for treating hirsutism, but some patients may feel worse on low-dose maintenance therapy.

Cyproterone acetate effectively treats sexual disorders by reducing sexual functions and is generally well-tolerated.

DHT deficiency may disrupt rat epididymis function by affecting estrogen receptors.