February 2010 in “ePrints Soton (University of Southampton)” Male sexual differentiation is regulated independently, while female differentiation occurs in an androgenic environment, affecting conditions like congenital adrenal hyperplasia.
January 2003 in “Elsevier eBooks” Androgens and other hormones affect hair growth and skin conditions like acne.
Dermal stem cells help regenerate hair follicles and heal skin wounds.
532 citations
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August 2011 in “Journal of the American Academy of Dermatology” Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.
234 citations
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April 2000 in “Gene” Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.
74 citations
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June 2018 in “Cell death and disease” Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.
66 citations
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June 2010 in “Experimental Dermatology” The hair follicle is a great model for research to improve hair growth treatments.
52 citations
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February 2018 in “Diabetology & Metabolic Syndrome” Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.
51 citations
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January 2024 in “Nanoscale” Nano-PROTACs could improve drug targeting and delivery by using nanotechnology.
23 citations
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January 2022 in “Biomaterials Science” Non-viral vectors show promise for safe and effective CRISPR/Cas9 gene editing in treating diseases.
3 citations
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February 2025 in “Journal of PHYSIOLOGICAL ANTHROPOLOGY” Certain genes are linked to skin aging, like wrinkles and pigmentation changes.
May 2025 in “Cermin Dunia Kedokteran” Leukokoria can signal Coats disease or other retinal issues, requiring early detection to prevent severe outcomes.
January 2019 in “Springer Reference Medizin” Follicle Stimulating Hormone is important for fertility.
January 2018 in “Stem cell biology and regenerative medicine” The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
November 2013 in “John Wiley & Sons, Ltd eBooks” The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.
January 2013 in “The Journal of Sexual Medicine” The document suggests that finasteride may cause depression and suicidal thoughts, while prostate surgery does not harm sexual health.
June 2011 in “CRC Press eBooks” Low-Level Laser Therapy can stimulate healing and cell function, potentially leading to wider medical use.
10 citations
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December 2015 in “Clinics in Dermatology” Diabetes can lead to blindness and skin problems, and managing blood sugar and blood pressure is crucial to prevent these complications.
4 citations
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May 2025 in “npj Parkinson s Disease” PINK1 is important for controlling gut immune responses linked to early Parkinson's disease.
December 2024 in “Frontiers in Veterinary Science” Dorper sheep's wool shedding is linked to specific genes and pathways, which may help understand human hair growth.
363 citations
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March 2017 in “Nature Communications” Stem cells help heal wounds by rapidly dividing and migrating to the wound edge.
308 citations
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September 2010 in “Nucleic acids research” Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.
163 citations
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April 2019 in “Nature Communications” Mechanical stretching of the skin can promote hair growth by activating certain immune cells.
149 citations
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July 2014 in “Cold Spring Harbor Perspectives in Medicine” The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.
141 citations
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September 2016 in “European Journal of Dermatology” Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.
123 citations
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December 2015 in “Journal of Neuroendocrinology” New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.
118 citations
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October 2013 in “Trends in Genetics” The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.
77 citations
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February 2017 in “Stem Cell Reports” SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.
59 citations
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November 2010 in “Circulation Research” Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.
58 citations
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December 2018 in “Nature Communications” Male pattern baldness is mostly inherited, involves many genes, and is linked to other traits like early puberty and strong bones.