86 citations
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May 2008 in “Cytokine & growth factor reviews” TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.
86 citations
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December 2001 in “Experimental dermatology” Mutant mice help researchers understand hair growth and related genetic factors.
85 citations
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May 2019 in “Journal of neuroendocrinology” The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.
82 citations
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August 2017 in “Cell Reports” An imbalanced gut and lack of biotin can cause hair loss in mice.
82 citations
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August 2006 in “Pharmacology, Biochemistry and Behavior” Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.
76 citations
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November 2009 in “Medical Clinics of North America” Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.
75 citations
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August 2018 in “Biochemical pharmacology” Targeting the skin's endocannabinoid system could help treat skin disorders.
70 citations
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February 2017 in “Dermatologic Surgery” Treatment with plasma rich in growth factors improved hair density and thickness for hair loss patients.
70 citations
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July 2016 in “Aging” Targeting dermal adipocytes may help combat skin aging.
67 citations
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August 2013 in “International Journal of Cosmetic Science” Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.
67 citations
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May 2010 in “Journal of The American Academy of Dermatology” Some chemotherapy can cause permanent hair loss.
66 citations
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March 2018 in “British journal of dermatology/British journal of dermatology, Supplement” An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.
60 citations
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June 1997 in “Journal of The American Academy of Dermatology” Apoptosis is crucial for healthy skin and treating skin diseases.
59 citations
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February 2012 in “Journal of Dermatological Science” Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.
58 citations
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June 2018 in “Scientific reports” Researchers found 15 new genetic links to skin traits in Japanese women.
57 citations
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January 1986 in “The Prostate” The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
56 citations
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February 2012 in “Cell Cycle” MicroRNAs are crucial for controlling skin development and healing by regulating genes.
54 citations
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October 2019 in “Cochrane library” Some drugs may reduce prostatitis symptoms short-term with few side effects.
54 citations
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October 2023 in “Oncogene” p63 is essential for controlling epithelial stem cells and tissue health.
53 citations
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August 2019 in “American journal of human genetics” FOXN1 gene variants cause low T cells and immune issues from birth.
52 citations
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October 2012 in “Journal of Dermatological Science” The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
49 citations
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October 2017 in “Nutrients” Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.
49 citations
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August 2004 in “The FASEB Journal” Mice with human skin protein K8 had more skin problems and cancer.
46 citations
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March 2015 in “Regeneration” Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.
46 citations
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December 2003 in “Advances in neonatal care” Assessing newborn scalp hair can reveal important health information.
45 citations
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March 2015 in “Clinical Endocrinology” Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.
45 citations
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March 2010 in “Journal der Deutschen Dermatologischen Gesellschaft” A systematic approach is crucial for managing hair loss in women.
44 citations
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November 1998 in “Australasian Journal of Dermatology” Accurate diagnosis is key for treating different kinds of hair loss, and immune response variations may affect the condition and treatment results.
43 citations
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October 2013 in “Journal of Investigative Dermatology” Organotypic culture systems can grow skin tissues that mimic real skin functions and are useful for skin disease and hair growth research, but they don't fully replicate skin complexity.
43 citations
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March 2009 in “Journal of Cellular and Molecular Medicine” TGF-β2 plays a key role in human hair growth and development.