research Periodontal Ligament Stem Cells: Regenerative Potency in Periodontium
Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.
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research CME examination
Control symptoms and use safe treatments for skin conditions like lichen planopilaris and chronic cutaneous lupus erythematosus.
research Low-Level Light/Laser Therapy Versus Photobiomodulation Therapy
Photobiomodulation Therapy (PBMT) is recommended as a more inclusive term and shows potential benefits in various treatments.
research Liquid chromatographic-mass spectrometric method for determination of drug content uniformity of two commonly used dermatology medications in a split-tablet dosage form
Splitting non-scored tablets can lead to uneven drug distribution, posing risks.
research Intralesional Platelet-Rich Plasma in the Treatment of Oral Lichen Planus: Review Article
Platelet-rich plasma is a safe and effective treatment for oral lichen planus.
research Papillon-Lefévre Syndrome: A Rare Case Report and a Brief Review of Literature
Early detection and multidisciplinary treatment are crucial for managing Papillon-Lefévre syndrome.
research Metal doped keratin film standard for LA-ICP-MS determination of lead in hair samples
A new method accurately measures lead levels in hair to assess exposure.
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research The New Classification Criteria of Systemic Lupus Erythematosus
The 2012 SLICC criteria provide an updated method for classifying Systemic Lupus Erythematosus.
research In‐silico Screening of ATP‐competitive Inhibitory Activities of Phytochemicals against Janus Kinase 3 and Its In‐vitro Evaluation
Poncirin is a promising inhibitor of Janus Kinase 3, potentially better than tofacitinib.
research 307 Phenotypic-genotypic expansion of plectinopathy in a patient with muscular dystrophy and immune-mediated myasthenia gravis
A patient with a new PLEC gene mutation showed symptoms of both muscular dystrophy and myasthenia gravis, which improved with steroid treatment.
research Sjogren-Larsson Syndrome
If someone has scaly skin, muscle stiffness, and intellectual disability, doctors should consider Sjogren-Larsson Syndrome, but other conditions if more symptoms are present.
research Photobiomodulation and its influence on the regulation of gene expression in human cells: a narrative literature review
Photobiomodulation can influence gene and protein expression related to healing and inflammation.
research PLCD1 and Pilar Cysts
The research linked PLCD1 gene variants to the development of trichilemmal cysts.
research Lichen planopilaris is characterized by immune privilege collapse of the hair follicle's epithelial stem cell niche
Lichen planopilaris may be an autoimmune disease causing hair loss due to immune system issues in hair follicles.
research IL-17 Expression in the Perifollicular Fibrosis in Biopsies From Lichen Planopilaris
Blocking IL-17 might help treat the hair loss condition Lichen planopilaris.
research Journal of Pigmentary Disorders
research New Insight Into the Immunostaining Method Suitable for the Pilosebaceous Complex Unit
The study found that a one-step antibody method is better than the LSAB method for accurately studying hair follicle structures without false positives.
research ISHRS Best Practices Survey Project MODULE: Who Does What SUMMARY ANALYSIS
research Lichen Planopilaris
Lichen Planopilaris is a hair loss condition best treated early with various medications, including hydroxychloroquine, to prevent permanent baldness.
research Netherton syndrome: effect on ichthyosis linearis circumflexa with dupilumab
This case study evaluates the efficacy of Dupilumab in treating a 4-year-old girl with Netherton Syndrome (NS), specifically focusing on its impact on eczema and ichthyosis linearis circumflexa (ILC). Dupilumab treatment led to significant improvements in eczema, pruritus, and hair condition, with a more than 40% improvement in SCORAD, EASI, and CDLQI scores, and a substantial reduction in serum IgE levels. However, the treatment did not improve ILC, which persisted with recurrent flares. The study suggests that while Dupilumab effectively targets the Th2-driven pathways associated with eczema, it does not address the IL-17/IL-36 pathways implicated in ILC. This highlights the need for further research to develop targeted therapies for the ichthyotic lesions in NS.
research Efficacy and safety of tofacitinib in the treatment of adults with lichen planopilaris: A randomized placebo-controlled trial
research Lichen planopilaris epidemiology: a retrospective study of 80 cases
Lichen planopilaris mostly affects women with fair skin and can look different on each person, needing early treatment to prevent hair loss.
research Impact of Combined Baricitinib and FTI Treatment on Adipogenesis in Hutchinson–Gilford Progeria Syndrome and Other Lipodystrophic Laminopathies
Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.
research Differential diagnoses of pseudolymphomatous folliculitis: considerations as regards one case
Accurate diagnosis of pseudolymphomatous folliculitis is crucial to avoid mistaking it for more serious conditions.