research Applications of Human Pluripotent Stem Cell–Derived Skin Organoids in Dermatology
Skin organoids from stem cells can help study and treat skin issues but face some challenges.
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30 / 352 results research Merkel cell polyomavirus infection and persistence modelled in skin organoids
Merkel cell polyomavirus can infect and persist in skin cells, evading the immune system, but certain treatments can control it.
research Skin organoids: A new human model for developmental and translational research
Skin organoids are a promising new model for studying human skin development and testing treatments.
research iPSC-based approach for human hair follicle regeneration
The document concludes that using stem cells to regenerate hair follicles could be a promising treatment for hair loss, but there are still challenges to overcome before it can be used clinically.
research Therapeutic Potential of Patient iPSC-Derived iMelanocytes in Autologous Transplantation
Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.
research 545 Skin Organoids derived from NCSTN mutated patient-induced pluripotent stem cells recapitulate Hidradenitis Suppurativa pathogenic hallmarks
Skin organoids with NCSTN mutation show changes in hair follicle development and higher inflammation, key features of Hidradenitis Suppurativa.
research Development of pluripotent stem cell-derived epidermal organoids that generate effective extracellular vesicles in skin regeneration
Stem cell-derived organoids can improve skin healing.
research Hair Follicle Development in Mouse Pluripotent Stem Cell-Derived Skin Organoids
Scientists grew hair follicles from mouse stem cells in a lab setting.
research Hair Follicle Organoids Using Human iPSC-Derived Ectodermal Precursor Cells for Hair Regenerative Medicine
Human stem cells can help grow hair for regenerative medicine.
research Dermal Microvascular Responses of Human Induced Pluripotent Stem Cell–Derived Skin Organoids to Inflammation and Injury
Skin organoids can mimic human skin responses to injury and inflammation, making them useful for studying skin diseases and testing treatments.
research Modeling of solar UV-induced photodamage on the hair follicles in human skin organoids
Sunlight exposure damages hair follicles, but certain stem cell-derived particles can reduce this damage and help with hair regeneration.
research A skin organoid-based infection platform identifies an inhibitor specific for HFMD
NSC167409 can effectively inhibit the virus causing hand, foot, and mouth disease.
research Organoid‐Guided Precision Medicine: From Bench to Bedside
Organoid technology is improving personalized medicine by better predicting drug responses and treatments.
research Organoids in skin wound healing
Skin organoids help improve wound healing and tissue repair.
research Integrating stem cell biology and organoid technology for skin regenerative therapies
Combining stem cells and organoids could improve skin regeneration treatments.
research Bioengineered skin organoids: from development to applications
Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
research The empowering influence of air-liquid interface culture on skin organoid hair follicle development
Air-liquid interface culture improves hair follicle development in skin organoids.
research Mechanical force drives the initial mesenchymal-epithelial interaction during skin organoid development
Mechanical force is important for the first contact between skin cells and hair growth in mini-organs.
research Organoid technology for tissue engineering
Organoid technology helps create mini-organs for studying diseases and testing drugs.
research Human hair regeneration using organoids and hair-on-chip technologies
Organoids and hair-on-chip technologies show promise for hair regeneration but face clinical challenges.
research Functional ectodermal organ regeneration as the next generation of organ replacement therapy
The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.
research Pre-aggregation of scalp progenitor dermal and epidermal stem cells activates the WNT pathway and promotes hair follicle formation in in vitro and in vivo systems
Grouping certain skin cells together activates a growth pathway that helps create new hair follicles.
research Functional Skin Grafts: Where Biomaterials Meet Stem Cells
Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
research Trajectory of hiPSCs derived neural progenitor cells differentiation into dermal papilla-like cells and their characteristics
Human stem cells were turned into cells similar to those that help grow hair and showed potential for hair follicle formation.
research Generation of Skin Organoids: Potential Opportunities and Challenges
Skin organoids from stem cells could better mimic real skin but face challenges.
research Generation and characterization of hair-bearing skin organoids from human pluripotent stem cells
Scientists created hair-growing skin models from stem cells, which could help treat hair loss and skin diseases.
research Biofabrication of Human Skin with Its Appendages
Current methods can't fully recreate skin and its features, and more research is needed for clinical use.
research Innovations in skin microphysiological systems for nonclinical testing and FDA modernization
New technologies replicate human skin for testing without animals.
research Applications of Engineered Skin Tissue for Cosmetic Component and Toxicology Detection
Engineered skin tissue is a promising tool for safer cosmetic testing.
research Organ regeneration based on developmental biology: past and future
Scientists have made progress in growing mini-organs and regenerating parts of the skin, with plans to treat hair loss in a future trial.