61 citations
,
March 2006 in “Colloids and surfaces. B, Biointerfaces” Lecithin microemulsion safely delivers tetracaine hydrochloride through the skin.
2 citations
,
December 2022 in “Journal of toxicologic pathology” Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.
19 citations
,
July 2019 in “Biomedical Microdevices” Microneedles can cause side effects like infection and allergic reactions, and precautions like test spots and sunscreen are recommended.
1 citations
,
August 2017 in “Asian Journal of Pharmaceutical and Clinical Research” The 1% ethyl acetate fraction ethosomal gel from Nothopanax scutellarium leaves promotes hair growth but can mildly irritate the skin.
15 citations
,
July 1997 in “Clinics in Dermatology” Traditional Chinese medications can cause skin reactions, and better testing and reporting are needed to identify allergens.
2 citations
,
March 2015 in “Toxicology and Environmental Health Sciences” Rice bran extract caused moderate skin irritation but no eye irritation, while a diluted essence was not irritating to skin and only slightly to guinea pigs.
December 2023 in “International Journal of Newgen Research in Pharmacy & Healthcare” Both herbal and synthetic shampoos in India are generally safe and effective.
September 1995 in “American Journal of Contact Dermatitis” Antiyeast treatments work better for seborrheic dermatitis than steroids, and other findings include increased skin bacteria under plastic wrap, a nasal cell defect in Staphylococcus aureus carriers, quick resolution of certain skin reactions, high rubber latex allergy in spina bifida patients, and glyceryl monopentadecanoate's effectiveness for male hair loss.
1 citations
,
January 2022 in “Indonesian Journal of Pharmaceutical Science and Technology” Cinchona extract cream safely enhances hair growth.
2 citations
,
January 2009 A natural extract-based hair growth product was developed and showed promise in preliminary tests.
August 2025 in “South African Journal of Botany” Formulation B of the herbal hair oil promotes hair growth better than standard treatments and is safe for use.
July 2017 in “Journal of Young Pharmacists” Nothopanax scutellarium leaves can promote hair growth but may mildly irritate the skin.
2 citations
,
September 2016 in “Journal of Dermatological Science” Squarticles, tiny particles made from sebum-derived lipids, can effectively deliver minoxidil, a hair growth drug, directly to hair follicles and skin cells, with less skin penetration and more tolerability.
1 citations
,
April 2025 in “International Journal for Research in Applied Science and Engineering Technology” Herbal face packs are a safe and effective alternative to synthetic skincare products.
1 citations
,
October 2021 in “International journal of pharmaceutics and drug analysis” The Aloe Vera shampoo worked better for hair care than a regular shampoo.
November 2025 in “Journal of Pharmacognosy and Phytochemistry” The flaxshine hair mask effectively conditions hair using natural ingredients.
23 citations
,
January 2001 in “International journal of toxicology” St. John's Wort extract and oil safety in cosmetics is unclear; more data needed on photosensitization, toxicity, and human irritation.
5 citations
,
August 2016 in “International Journal of Cosmetic Science” Shampoo coacervates can cause scalp irritation due to released surfactants.
June 2025 in “Healthy-Mu Journal” The optimized Cinchonine gel effectively fights acne bacteria and is safe for twice-daily use.
61 citations
,
January 2018 in “Cosmetics” Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.
January 2020 in “Journal of Pharmacognosy and Phytochemistry” The VCO-based herbal hair tonic is effective, safe for hair loss treatment, and can be mass-produced.
May 2023 in “Jurnal farmasi sains dan praktis” The hair tonic with cinnamon oil and coconut oil was stable and caused very mild irritation.
June 2017 in “Asian journal of pharmaceutical and clinical research” Green tea extract gel safely increases eyelash length.
38 citations
,
June 2005 in “Contact Dermatitis” Patient had scalp allergy from minoxidil; test helped identify cause and suggest alternative treatments.
Ajwain seed extract improved skin healing and hair growth in a mouse skin irritation model.
October 2001 in “WORLD SCIENTIFIC eBooks” Many substances, including chemicals and metals, can cause skin reactions; careful handling and identification of allergens are crucial to prevent dermatitis.
October 2022 in “Asian journal of healthy and science” Mother-in-law's tongue leaf extract at 20% concentration significantly promotes hair growth in male rabbits.
16 citations
,
December 2016 in “Skin appendage disorders” Nickel, cobalt, balsam of Peru, fragrance mix, carba mix, and propylene glycol are common allergens causing scalp contact dermatitis.
August 2025 in “Tropical Journal of Natural Product Research” Celery extract and candlenut oil effectively and safely boost hair growth.
May 2020 in “JAAD case reports” Using anthralin and calcipotriene together might help treat tough cases of alopecia areata, but more research is needed to understand how it works.