59 citations
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August 2004 in “Human Reproduction Update” Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.
59 citations
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September 2003 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.
36 citations
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June 2014 in “PLOS ONE” Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.
18 citations
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January 2013 in “Psychoneuroendocrinology” Neonatal neurosteroid levels affect adult brain function and behavior.
14 citations
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January 2008 in “Dermatology Online Journal” Hormonal therapies like cyproterone acetate and spironolactone may help some women with hair loss, but finasteride 1mg is not useful, and the effectiveness of other treatments is still unclear.
13 citations
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May 2007 in “Journal of Endocrinology” Synthetic 19-norprogestins promote bone cell growth and function through their non-phenolic metabolites.
11 citations
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March 2023 in “Frontiers in Nutrition” Hair analysis can detect small changes in dietary zinc intake.
10 citations
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July 2018 in “Our Dermatology Online” Some vitamins and minerals are important for preventing hair loss, but treating hair loss with them without a known deficiency is not proven effective.
1 citations
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January 2022 in “Springer eBooks” December 2009 in “Eclética Química” A simple and fast method accurately measures minoxidil in pharmaceuticals.
January 2008 in “Dermatology Online Journal” Hormonal therapy like cyproterone acetate and spironolactone may help female hair loss, but more research is needed, especially for pre-menopausal women.
January 2021 in “HAMDAN MEDICAL JOURNAL” Finasteride treats hair loss and reduces prostate cancer risk.
29 citations
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April 2020 in “Biomolecules” Brassinosteroids may be useful in treating cancer, infections, and other diseases.
344 citations
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June 2006 in “American Journal Of Pathology” Human hair follicles can provide stem cells for regenerative medicine.
245 citations
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October 2015 in “Nature medicine” Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.
169 citations
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February 2018 in “Immunity” Inactive stem cells in hair follicles and muscles can avoid detection by the immune system.
139 citations
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May 2020 in “Stem Cell Research & Therapy” Exosomes from stem cells help wounds heal faster by affecting specific cell signals.
101 citations
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July 1998 in “Journal of Investigative Dermatology” UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.
82 citations
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July 2012 in “Brain pathology” High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.
67 citations
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September 2017 in “Cell Reports” Caloric restriction improves skin and fur structure but can cause muscle loss and movement issues.
52 citations
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May 2011 in “APOPTOSIS” Hydroxyl radicals cause hair follicle cell death during chemotherapy by reducing Bcl-2 protein levels.
44 citations
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September 2016 in “American Journal Of Pathology” Neural crest-derived progenitor cells in the cornea could help treat corneal issues without transplants.
37 citations
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December 2001 in “Journal of Investigative Dermatology” Leptin may play a role in hair growth and hair follicle health.
33 citations
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October 2006 in “European Journal of Immunology” The CD44-CD49d complex boosts T cell activation and survival in autoimmune disease.
25 citations
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January 2012 in “Proteome Science” Adipose stem cells show common protein changes as they grow, especially involving S100A6.
24 citations
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November 2019 in “Experimental Dermatology” PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.
20 citations
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December 2020 in “Frontiers in Immunology” The immune processes causing VKH and vitiligo are similar in dogs and humans.
19 citations
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September 2013 in “Molecular Medicine Reports” Human hair follicle stem cells can become smooth muscle cells using specific growth factors.
18 citations
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January 2021 in “Theranostics” The targeted nanohybrids effectively reduced psoriasis symptoms and improved skin health.
16 citations
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September 2006 in “The Journal of Immunology” MILL molecules are unique immune proteins in mice that don't need TAP to appear on cell surfaces.