90 citations
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July 2020 in “Stem Cell Research & Therapy” Stem cell vesicles can reduce skin aging from UVB by lowering inflammation and oxidative stress.
88 citations
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August 2019 in “Nature communications” Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.
79 citations
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March 1999 in “The journal of investigative dermatology/Journal of investigative dermatology” Procyanidin compounds from grape seeds were found to significantly increase mouse hair growth.
72 citations
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January 2012 in “Annals of Dermatology” IGF-I promotes hair growth by keeping hair follicles in the growth phase longer.
60 citations
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July 2011 in “Stem Cells and Development” Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
50 citations
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February 2018 in “Biomedicine & pharmacotherapy” Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.
42 citations
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March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
40 citations
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August 2018 in “Skin appendage disorders” Some alternative treatments for hair loss might work, but more research is needed.
38 citations
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September 2011 in “PLOS ONE” Activin B helps heal skin wounds and grow hair by activating a specific cell signaling pathway.
35 citations
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February 2023 in “Biomolecules” Granzyme B is important in autoimmune skin diseases and could be a new treatment target.
32 citations
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April 2016 in “Journal of Obstetrics and Gynaecology Research” Women with severe types of PCOS are more likely to have metabolic syndrome, and belly fat is a key predictor of this risk.
29 citations
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February 2011 in “PloS one” Astressin-B can reverse and prevent hair loss in stressed mice.
28 citations
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December 2019 in “Skin appendage disorders” Some medications might reverse gray hair, especially those that reduce inflammation or stimulate pigment production, and vitamin B might help.
26 citations
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November 2002 in “Planta medica” Extracts from Cercidiphyllum japonicum wood can stimulate mouse hair cell growth like common hair growth treatments.
25 citations
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November 2001 in “Kidney International” Male hormones worsen kidney transplant damage, but blocking them helps.
24 citations
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March 2018 in “Pigment Cell & Melanoma Research” The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.
24 citations
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March 2018 in “Experimental Dermatology” Treg dysfunction is linked to various autoimmune skin diseases, and understanding Treg properties is key for new treatments.
23 citations
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March 2019 in “Environmental Chemistry Letters” Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.
23 citations
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February 2019 in “International Journal of Molecular Sciences” Activin B can boost hair growth by promoting cell proliferation and cell cycle progression.
19 citations
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April 2015 in “European Journal of Pharmacology” Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.
19 citations
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January 2015 in “Current problems in dermatology” Ultraviolet rays damage hair, smoking may cause hair loss, and good nutrition is important for hair health, but genetics mainly decide hair thickness.
19 citations
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August 2010 in “Journal der Deutschen Dermatologischen Gesellschaft” Certain plant extracts can effectively treat skin conditions like athlete's foot, chronic vein problems, sun damage, skin growths, vitiligo, and hair loss, and may also improve skin appearance.
18 citations
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January 2015 in “International Journal of Trichology” Intralesional steroids are more effective for hair regrowth in alopecia areata than NBUVB, but combining them doesn't improve results.
16 citations
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March 2018 in “Seminars in Oncology” The document concludes that pregnancy and cancer share immune evasion tactics, but more research is needed before using checkpoint blockade immunotherapy in pregnant cancer patients to avoid harm to the placenta.
16 citations
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September 2008 in “American Journal of Orthodontics and Dentofacial Orthopedics” Wearing orthodontic headgear can cause reversible hair loss if detected early.
15 citations
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December 2018 in “International journal of environmental research and public health/International journal of environmental research and public health” EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.
14 citations
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January 2006 in “Skin pharmacology and physiology” Procyanidin compounds from apples and barley promote hair growth and prevent hair cell death.
12 citations
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June 2019 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics” Activating TRPV3 channels stops hair growth by killing hair follicle cells.
11 citations
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June 2012 in “Human Reproduction Update” The conclusion is that there is a high demand for new contraceptives that provide both pregnancy prevention and protection against STIs, along with additional health benefits.
11 citations
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August 1988 in “PubMed” Interferon therapy is a promising and safe treatment for hepatitis B in Southeast Asia.