86 citations
,
May 2002 in “Journal of Investigative Dermatology” A new keratin, hK6irs1, is found in all layers of the hair follicle's inner root sheath.
22 citations
,
February 2000 in “Journal of the American Academy of Dermatology” Eosinophils are not a reliable marker for diagnosing alopecia areata.
82 citations
,
July 2012 in “Brain pathology” High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.
4 citations
,
December 1995 in “Anthropologischer Anzeiger” Family members have similar hair protein patterns, which could be useful for genetic studies.
56 citations
,
November 1958 in “The Journal of Cell Biology” A unique skin cell similar to hair bulb melanocytes was identified, with better preservation using permanganate fixation.
130 citations
,
April 2003 in “Journal of Investigative Dermatology” Four specific keratins in hair follicles help understand hair structure and function.
26 citations
,
February 1998 in “DNA and Cell Biology” K6 gene expression can be controlled and manipulated in mice for studying skin disorders.
1 citations
,
November 2016 in “International Journal of Research in Dermatology” The study found no significant link between the symptoms, tissue analysis, and immunofluorescence results in scarring hair loss conditions.
February 2023 in “Research Square (Research Square)” Blocking IL-17 can reduce skin inflammation in a mouse model of pityriasis rubra pilaris.
10 citations
,
April 2013 in “Veterinary dermatology” A new skin disease in four Labrador retrievers responded well to immunosuppressive treatment.
April 2023 in “Journal of Investigative Dermatology” Long-term Imiquimod treatment causes initial skin inflammation that lessens over time, and topical corticosteroids reduce this inflammation and cytokines in a mouse model of psoriasis.
January 2023 in “Open Life Sciences” VEGFR-2 activation is likely involved in hair follicle growth, survival, and development.
37 citations
,
January 1986 in “Carcinogenesis” ODC expression in mouse skin and tumors is varied and can be inhibited by retinoic acid or cycloheximide.
16 citations
,
November 2005 in “Journal of Clinical Pathology” CD1d expression in scalp skin and hair follicles changes with the hair cycle and may help protect against microbes.
January 2003 in “Jiepouxue zazhi” HHK can help restore skin structure.
18 citations
,
May 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Different parts of the body have unique immune characteristics in their skin.
7 citations
,
January 2022 in “Biomedicines” Cells from the lower part of hair follicles are a promising, less invasive option for immune system therapies.
April 2018 in “Journal of Investigative Dermatology” Melanogenesis-related proteins may trigger immune responses in alopecia areata patients.
6 citations
,
November 2011 in “Journal of Dermatological Science” A new gene mutation may allow some piebaldism patients to regain skin color in white patches.
12 citations
,
January 1991 in “Acta Dermato Venereologica” Basal cell epithelioma-like changes are most similar to normal basal cells.
9 citations
,
July 2014 in “PubMed” Different S100 proteins have specific roles in various parts of the hair follicle.
April 2023 in “Journal of Investigative Dermatology” Higher PD-1 levels are linked to fewer immune cells in hair follicles in alopecia areata.
7 citations
,
June 2017 in “Journal of Cutaneous Pathology” Cystic panfolliculoma resembles hair follicle tumors due to specific cell interactions.
July 2023 in “Clinical, cosmetic and investigational dermatology” Reflectance confocal microscopy helped tell periorificial dermatitis apart from similar skin conditions.
14 citations
,
January 2020 in “Advances in Dermatology and Allergology” Higher interleukin-15 levels are linked to more severe alopecia areata, but not to age or gender.
4 citations
,
August 2013 in “Chinese Medical Journal” A specific gene mutation in KRT86 is linked to hair disorder in a Chinese Han family.
2 citations
,
December 2017 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” The conclusion is that a new method could improve the identification of autoimmune targets in alopecia areata, despite some limitations.
58 citations
,
May 2004 in “British Journal of Dermatology” Diphenylcyclopropenone treatment helps hair growth in alopecia areata by promoting blood vessel growth and cell survival.
54 citations
,
November 1994 in “Differentiation” Trichohyalin is found in non-hair tissues and works with filaggrin in certain skin areas and conditions.
5 citations
,
June 2012 in “Journal of Investigative Dermatology” A new mouse model for vitiligo helps study immune responses and potential treatments.