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Tp63-Expressing Adult Epithelial Stem Cells Cross Lineage Boundaries Revealing Latent Hairy Skin Competence

research Tp63-expressing adult epithelial stem cells cross lineages boundaries revealing latent hairy skin competence

8 citations , November 2020 in “Nature Communications”

Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.

research Progenitor cells expressing nestin, a neural crest stem cell marker, differentiate into outer root sheath keratinocytes

12 citations , July 2019 in “Veterinary Dermatology”

Nestin-expressing progenitor cells become outer root sheath keratinocytes.

research Establishment and molecular characterization of human dermal mesenchymal-like stem cells derived from human scalp biopsy of androgenetic alopecia patient

4 citations , January 2013 in “Stem cell discovery”

Researchers created a cell line from a hair follicle to study hair loss.

Faculty Opinions Recommendation of Live Imaging of Stem Cell and Progeny Behavior in Physiological Hair-Follicle Regeneration

research Faculty Opinions recommendation of Live imaging of stem cell and progeny behaviour in physiological hair-follicle regeneration.

December 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

The conclusion is that the dermal papilla is crucial for hair follicle regrowth, and hair follicles undergo significant structural changes in addition to cell division during regeneration.

research Generating iPSCs with a High-Efficient, Non-Invasive Method—An Improved Way to Cultivate Keratinocytes from Plucked Hair for Reprogramming

3 citations , June 2022 in “Cells”

The conclusion is that the new method makes collecting cells from plucked hair to create stem cells more efficient and less invasive.

research The HOXC13-controlled expression of early hair keratin genes in the human hair follicle does not involve TALE proteins MEIS and PREP as cofactors

18 citations , November 2005 in “Archives of Dermatological Research”

research Towards expansion of human hair follicle stem cells in vitro

14 citations , April 2011 in “Cell Proliferation”

Scientists can grow human hair follicle stem cells in a lab without changing their nature, which could help treat hair loss.

research Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration

3 citations , December 2013 in “Journal of Cell Science”

Keratin 79 cells help form and regenerate hair canals.

research 613 Assessment of the induction and morphogenic potential of human hair matrix cells and dermal papilla fibroblasts ex vivo

1 citations , September 2019 in “Journal of Investigative Dermatology”

Human hair matrix cells and dermal papilla fibroblasts can form early hair follicle structures but don't produce hair shafts yet.

research Long-term renewal of hair follicles from clonogenic multipotent stem cells

291 citations , October 2005 in “Proceedings of the National Academy of Sciences of the United States of America”

Adult stem cells from rat whisker follicles can regenerate hair follicles and sebaceous glands.

research Human hair follicle and interfollicular keratinocyte reactivity to mouse HPV16-transformed cells: An in vitro study

9 citations , July 2008 in “Oncology Reports”

HPV16-transformed cells can change human skin cell properties, aiding tumor growth.

research Programming of induced pluripotent stem cells for hair follicle regeneration.

June 2015 in “PubMed”

research N1-methylspermidine, a stable spermidine analog, prolongs anagen and regulates epithelial stem cell functions in human hair follicles

13 citations , July 2015 in “Archives of dermatological research”

N1-methylspermidine helps hair growth and reduces inflammation in hair follicles.

Optogenetically Controlled TrkA Activity Improves the Regenerative Capacity of Hair-Follicle-Derived Stem Cells to Differentiate into Neurons and Glia

research Optogenetically Controlled TrkA Activity Improves the Regenerative Capacity of Hair‐Follicle‐Derived Stem Cells to Differentiate into Neurons and Glia

6 citations , September 2020 in “Advanced Biology”

Blue-light activation of TrkA improves hair-follicle stem cells' ability to become neurons and glial cells.

research Unconventional haircare

January 2023 in “Nature Immunology”

Certain immune cells help hair growth by regulating iron in the skin.

research Impaired differentiation potential of CD34-positive cells derived from mouse hair follicles after long-term culture

2 citations , June 2022 in “Scientific reports”

Mouse hair follicle stem cells lose their ability to change into different cell types after being grown for a long time.

research Expression of novel keratin associated protein 5 genes in the cuticle layer of human hair follicles

6 citations , April 2005 in “Journal of dermatological science”

The study found nine new hair protein genes in human hair follicles.

research Single cell analysis of transcriptome and open chromatin reveals the dynamics of hair follicle stem cell aging

3 citations , July 2023 in “Frontiers in Aging”

Hair follicle stem cells change states with age, affecting hair growth and aging.

research Recent progress in hair follicle stem cell markers and their regulatory roles

13 citations , February 2024 in “World Journal of Stem Cells”

New markers help understand and use hair follicle stem cells for regeneration.

research OCT4 maintains self-renewal and reverses senescence in human hair follicle mesenchymal stem cells through the downregulation of p21 by DNA methyltransferases

57 citations , January 2019 in “Stem Cell Research & Therapy”

OCT4 helps hair stem cells renew and fight aging, potentially aiding hair regrowth.

research Expression pattern of human hair keratin basic 1 (hHbl) in hair follicle and pilomatricoma

8 citations , April 1997 in “Experimental Dermatology”

hHbl gene is active in hair shaft cells and some pilomatricomas.

research Brief Report: Requirement of TACE/ADAM17 for Hair Follicle Bulge Niche Establishment

14 citations , June 2012 in “Stem Cells”

TACE/ADAM17 is essential for maintaining healthy hair and hair follicle stem cells.

research In vitro neural differentiation of CD34 + stem cell populations in hair follicles by three different neural induction protocols

18 citations , October 2014 in “In vitro cellular & developmental biology. Animal”

Hair follicle stem cells can become neural cells using different methods, with varying efficiency.

research Raising hairs

8 citations , June 2011 in “Nature Biotechnology”

Stem cell treatments can potentially treat baldness, with one trial showing hair growth after injecting a hair-stimulating complex, and no safety issues were reported.

research Supplementary Figures, Tables and Legends from Mobilizing Transit-Amplifying Cell-Derived Ectopic Progenitors Prevents Hair Loss from Chemotherapy or Radiation Therapy

March 2023

Boosting certain cell signals can prevent hair loss from chemotherapy and radiation.

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