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The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.

A new keratin 6 type in mice explains why some mice without certain keratin genes still have normal hair and nails.

Arabidopsis PCaP2 helps plants survive drought by linking ABA and SA signals.

New mutations in MBTPS2 reduce its function and cause IFAP syndrome with unusual symptoms.

Defects in certain proteins cause major heart abnormalities during early development.

GPC1 is important for hair growth by helping blood vessels form around hair follicles.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

Mouse hair follicle stem cells have a flexible chromatin state that supports skin health and hair growth.

Activating TRPV1 can boost hair growth by involving neurons, macrophages, and fibroblasts.

The diphosphonate was the most effective at preventing calcification in rats.

TP0427736 may help treat hair loss by blocking a specific protein and promoting hair growth.

Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.

New mutations in the DSG4 gene cause a rare hair condition.

An enzyme other than TNAP might be responsible for vitamin B-6 metabolism in the skin.

Rebamipide may help regrow hair by activating hair follicle stem cells.

Normal human melanocytes can avoid cell death through multiple pathways.

HAIRCARECUBE TM (HCC) helps hair products work better by getting active ingredients deeper into the hair.

Certain genetic variants in keratins increase the risk of tooth decay.

Increasing PBX1 reduces aging and cell death in hair follicle stem cells by boosting SIRT1 and lowering PARP1 activity.

The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.

TTNPB helps turn stem cells into neural stem cells, improving depression-like behaviors in rats.

Mice can correct hair follicle orientation without certain genes, but proper overall alignment needs those genes.

The MPA-ISO cocrystal improved solubility and dissolution rate, while the others did not.

Baricitinib 4 mg is effective and safe for treating severe alopecia areata.

Lack of a key enzyme causes severe skin issues and death in mice.

Lysosomal proteases and cytoplasmic enzymes help hair follicle cells develop and differentiate.

The PCR technique can identify genetic differences in a wool-related gene among different sheep breeds, which may help improve wool and pelt quality.

Deleting the MAD2L1 gene in mice led to rapid tumor growth despite chromosomal instability.