4 citations
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June 2007 in “PubMed” Engineered skin with specific cells can effectively repair skin and restore its function.
135 citations
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December 2006 in “PLoS Medicine” Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.
94 citations
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October 1994 in “The Journal of Cell Biology” Too much keratin 16 in mice skin causes abnormal skin thickening and structure.
47 citations
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January 2024 in “iScience” Stress keratins are expressed less in diseased skin and are linked to differentiation, inflammation, and immunity.
28 citations
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June 2021 in “Frontiers in immunology” A protein called lfTSLP is important in causing allergic and other skin diseases and could be a target for treatment.
23 citations
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July 2022 in “Nature Cell Biology” Targeting THY1 can improve skin repair and healing.
22 citations
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February 2023 in “Heliyon” The hydrogel significantly speeds up wound healing and supports skin cell growth.
17 citations
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May 2013 in “Journal of Investigative Dermatology” Mutations in β1 integrins cause embryonic death but have milder effects on skin.
14 citations
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March 2014 in “Experimental and Molecular Pathology” Sulfur mustard damages hair follicles and sebaceous glands in mice.
10 citations
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September 2023 in “Metabolites” Iron is crucial for skin health, with specific proteins recycling it to support skin functions and prevent its release.
4 citations
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January 2021 in “Cell transplantation” Scientists found the best time to transplant human stem cells for hair growth is between days 16-18 when they have the right markers and growth potential.
2 citations
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October 2012 in “Experimental Dermatology” Deleting the Sox21 gene changes hair lipid composition and increases cholesterol sulfate levels.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” EGFR deficiency causes significant changes in skin cells and hair follicles.
Some factors can either promote or inhibit hair growth.
GPC1 is important for blood vessel growth in hair follicles and could help treat hair loss.
Glypican-1 is important for hair follicle blood vessel growth and could be a target for treating hair loss.
September 2004 in “Experimental Dermatology” Key signals like Wnt and β-catenin are crucial for skin and hair development, with potential for treating skin disorders.
July 2023 in “Bioengineering & translational medicine” Mesenchymal stem cell proteins in a special gel improved healing of severe burns.
GPC1 is important for blood vessel growth in hair follicles and could help treat hair loss.
GPC1 is important for hair growth by helping blood vessels form around hair follicles.
65 citations
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August 2013 in “Acta Biomaterialia” The new matrix improves skin regeneration and graft performance.
30 citations
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February 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Plet-1 protein helps hair follicle cells move and stick to tissues.
13 citations
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January 2018 in “Yonsei Medical Journal” A specific gene mutation causes Olmsted syndrome.
8 citations
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August 2025 in “Journal of Translational Medicine” CD44 signaling can help heal wounds without scars.
1 citations
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December 2024 in “The Journal of Dermatology” The study developed mouse models to help research and treat hair and sweat gland issues.
August 2024 in “Cell Death and Disease” Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.
375 citations
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June 2013 in “Biochimica et biophysica acta. Molecular cell research” Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
138 citations
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June 2004 in “Journal of Investigative Dermatology” Involucrin gene expression is controlled by specific proteins and signaling pathways.
130 citations
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December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle melanocytes die during hair regression.
60 citations
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February 2014 in “Tissue Engineering Part A” Microporous scaffolds speed up skin healing and regeneration.