research Monilethrix: Beaded hair and hypotrichosis in a child
A 9-year-old girl has a rare hair disorder causing beaded, sparse hair.
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research KRT16 wt Allele
Mutations in the KRT16 gene can cause skin and nail disorders.
research Faculty Opinions recommendation of Hair cycle resting phase is regulated by cyclic epithelial FGF18 signaling.
FGF18 controls hair cycle rest and growth phases.
research Biology and Genetics of Hair
The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
research A Splice Site Mutation in the Gene of the Human Type I Hair Keratin hHa1 Results in the Expression of a Tailless Keratin Isoform
A genetic mutation in the hHa1 gene creates a smaller, but still functional, hair protein without causing hair problems.
research A novel monoclonal antibody to the outer root sheath cells
The new antibody, TYHF-1, specifically targets certain hair-related structures.
research Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle
Inhibiting Bmp signaling disrupts hair growth and differentiation.
research A Rapid Extraction Procedure of Human Hair Proteins and Identification of Phosphorylated Species.
A new method quickly extracts and identifies proteins from hair and other keratin sources.
research ELECTRON MICROSCOPE STUDIES OF HAIR AND WOOL
Hair and wool have complex microscopic structures with microfibrils and varying cystine content.
research Generation of folliculogenic human epithelial stem cells from induced pluripotent stem cells
Scientists created stem cells that can grow hair and skin.
research Characterization of a 300 kbp Region of Human DNA Containing the Type II Hair Keratin Gene Domain
The research identified six functional hair keratin genes and four pseudogenes, providing insights into hair formation and gene organization.
research Phospholipase C‐δ1 is an essential molecule downstream of Foxnl, the gene responsible for the nude mutation, in normal hair development
Phospholipase C-δ1 is crucial for normal hair development.
research The role of disulfide bond formation in the structural transition observed in the intermediate filaments of developing hair
Disulfide bonds are crucial for hair structure during keratinization.
research Gsdma3 is required for hair follicle differentiation in mice
The Gsdma3 gene is essential for normal hair development in mice.
research Hair keratin pattern in human hair follicles grown in vitro
Human hair follicles grown in vitro maintain normal keratin patterns and structure.
research Toluene Diisocyanate (TDI) Disposition and Co-Localization of Immune Cells in Hair Follicles
Toluene diisocyanate exposure can cause immune sensitization by interacting with proteins in hair follicles and sebaceous glands.
research Sequence and expression of human hair keratin genes
Human hair keratin genes are similar to mouse genes and are specifically expressed in hair follicles.
research Novel KRT83 and KRT86 mutations associated with monilethrix
New mutations in KRT83 and KRT86 are linked to the hair disorder monilethrix.
research Scalp biomarkers during dupilumab treatment support Th2 pathway pathogenicity in alopecia areata
Dupilumab treatment reduces Th2-related markers and helps hair growth in alopecia areata, showing Th2's role in the condition.
research Photoinduced formation of thiols in human hair
UV exposure damages hair, increasing thiols and altering protein structure.
research Morphologic and immunologic characterization of a canine isthmus mural folliculitis resembling pseudopelade of humans
Dogs have a skin condition like human pseudopelade, causing hair loss that doesn't improve with treatment.
research Masquerading of trichotillomania in a family with monilethrix
It's important to consider genetic hair disorders when diagnosing hair loss.
research Coenzyme Q10 has anti-aging effects on human hair
Coenzyme Q10 helps reduce aging in human hair.
research 544 Alopecia areata lesions show significant changes in immune and keratin biomarkers that correlate with clinical improvement with oral Janus kinase inhibitors PF-06651600 (JAK3) and PF-06700841 (TYK2/JAK1)
Oral JAK inhibitors improved alopecia areata by modulating immune responses and boosting hair growth.
research In brief
Pilomatricomas don't follow the usual hair follicle cell differentiation process.
research Colourless side of the nude mutation: Foxn1 and hair pigmentation
Foxn1 is essential for hair pigmentation by directing pigment transfer to hair cells.
research Alopecia areata exhibits cutaneous and systemic OX40 activation across atopic backgrounds
Alopecia areata patients show increased inflammation and OX40 activation, suggesting a new treatment target.
research Hair Matrix Cyst
Hair matrix cysts are rare skin nodules with unique features, often needing surgical removal.
research 874 Chromatin architectural protein CTCF controls epidermal barrier formation, hair follicle fate maintenance and suppresses inflammatory responses in the skin epithelium
The protein CTCF is essential for skin development, maintaining hair follicles, and preventing inflammation.
research Mechanism of cannabinoid incorporation in hair
Cannabinoids like THC and THCA get into hair through skin oils, not hair color.