research Sgk3 links growth factor signaling to maintenance of progenitor cells in the hair follicle
Sgk3 is essential for normal hair follicle growth and maintenance.
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research VDR is an essential regulator of hair follicle regression through the progression of cell death
Vitamin D Receptor is crucial for hair follicle shrinkage and cell death, affecting hair growth.
research Trends in the Development of New Drugs for Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.
research Allopregnanolone, the active metabolite of progesterone protects against neuronal damage in picrotoxin-induced seizure model in mice
research 4 Vitamin D resistance
Some people have genetic mutations that make them resistant to vitamin D, leading to rickets even with enough vitamin D intake.
research K15 & Id3 expression in intact and regenerating adult vibrissae rodent hair follicles
K15 and Id3 are important in hair follicle regeneration, with K15 increasing in early stages and Id3 responding later.
research Neuroactive steroids inhibit spinal reflex potentiation by selectively enhancing specific spinal GABAA receptor subtypes
Progesterone reduces spinal reflex activity by increasing certain GABA(A) receptor subtypes.
research Tangent screens are still useful in the assessment of vigabatrin induced visual field defects
Tangent screens help detect visual field defects from vigabatrin.
research Investigating the mechanisms underlying effects of testosterone on blood pressure in normotensive and hypertensive rats / Loh Su Yi
Testosterone raises blood pressure by affecting kidney function and brain gene regulation over time.
research The Princeton III Consensus Recommendations for the Management of Erectile Dysfunction and Cardiovascular Disease
The Princeton III Consensus recommends assessing cardiovascular risk in men with erectile dysfunction and prioritizing heart health before treating ED, especially in those with potential heart disease.
research Determination of rat 5α-reductase type 1 isozyme activity and its inhibition by novel steroidal oxazolines
New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.
research The Opening of Potassium Channels: A Mechanism for Hair Growth
research Enzalutamide/finasteride/goserelin/zoledronic-acid
![Discovery of (2S)-N-(6-Cyano-5-(Trifluoromethyl)Pyridin-3-Yl)-3-(6-(4-Cyanophenyl)-3,6-Diazabicyclo[3.1.1]Heptan-3-Yl)-2-Hydroxy-2-Methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment](/images/research/693e7bf6-2325-4ddc-a20f-3470db9f4516/small/25627.jpg)
research Discovery of (2S)-N-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-3-(6-(4-cyanophenyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)-2-hydroxy-2-methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment
A new topical treatment for hair loss shows strong hair growth effects with low toxicity.
research Abstract ED05-04: Presurgical models to effectively screen preventive agents
Presurgical models can effectively and affordably screen cancer prevention agents.
research BIOBRAN MGN-3
Biobran MGN-3 reduces chemotherapy side effects and improves quality of life for breast cancer patients.
research Bioconversion, Pharmacokinetics, and Therapeutic Mechanisms of Ginsenoside Compound K and Its Analogues for Treating Metabolic Diseases
Ginsenoside compound K shows promise for treating metabolic diseases like diabetes and obesity.
research Tumor Necrosis Factor in Sepsis
Topical eye β-blockers might cause hair loss, which usually gets better after stopping the medication.
research Biphasic Effects of Minoxidil on the Proliferation and Differentiation of Normal Human Keratinocytes
Minoxidil affects cell growth in two ways: low doses increase growth, while high doses slow it down and can be toxic.
research Ultrastructural Localization and Quantification of Extracellular Calcium Binding Sites in Mouse Vibrissa and Human Scalp Follicles
Hair growth drugs and epidermal growth factor do not change the calcium binding site gradient in hair follicles.
research ELEVATION OF DIASTOLIC BLOOD PRESSURE AND REDUCTION OF VASCULAR CONTRACTION IN MAGNESIUM DEFICIENT RAT MODEL
Magnesium deficiency raises diastolic blood pressure and reduces vascular contraction.
research LB1009 Baicalin, a component of the herbal medicine Baikal skullcap, inhibits epidermal necroptosis in SJS/TEN
Baicalin may help treat severe drug-induced skin reactions.
research Hydrogel forming microneedles loaded with VEGF and Ritlecitinib/polyhydroxyalkanoates nanoparticles for mini-invasive androgenetic alopecia treatment
New microneedle treatment with growth factors and a hair loss drug shows better and faster hair growth results than current treatments.
research Development of gene therapy for inner ear disease: Using bilateral vestibular hypofunction as a vehicle for translational research
Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.
research Cytokinin improves in vitro organogenesis, biological activities and blooming in Vitex negundo L. - An endangered medicinal plant
Cytokinins help Vitex negundo grow better and bloom more.
research Deletion of Deoxyribonucleic Acid Binding Domain of the Vitamin D Receptor Abrogates Genomic and Nongenomic Functions of Vitamin D
Removing part of the vitamin D receptor stops vitamin D from working properly.
research Clinical and Haemodynamic Study of Minoxidil in Moderately Hypertensive Patients
Minoxidil with a diuretic effectively lowers blood pressure in moderately hypertensive men with minimal side effects.
research Obituary: Professor Edward Carmeliet 1930 – 2021
Professor Edward Carmeliet was a leading figure in cardiac electrophysiology research.
research PRMT5 inhibition has a potent anti-tumor activity against adenoid cystic carcinoma of salivary glands
PRMT5 inhibitors effectively fight adenoid cystic carcinoma in salivary glands.
research Effective strategies to reduce pain during platelet-rich plasma scalp injections: A randomized split-scalp study
Ice packs and vibration devices can reduce pain during scalp injections.