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GlossaryKyoto Encyclopedia of Genes and Genomes

comprehensive database for understanding gene and protein functions

The Kyoto Encyclopedia of Genes and Genomes (KEGG) is a comprehensive database that helps researchers understand the functions and interactions of genes and proteins in various biological systems. It provides detailed maps of metabolic pathways, cellular processes, and disease mechanisms, making it a valuable tool for both basic and applied biological research.

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research Using WGCNA (weighted gene co-expression network analysis) to identify the hub genes of skin hair follicle development in fetus stage of Inner Mongolia cashmere goat

16 citations , December 2020 in “PloS one”

Researchers found WNT10A to be a key gene in developing goat hair follicles.

research RNA sequence analysis of dermal papilla cells’ regeneration in 3D culture

6 citations , October 2020 in “Journal of Cellular and Molecular Medicine”

3D culture helps maintain hair growth cells better than 2D culture and identifies key genes for potential hair loss treatments.

Proteomics-Based Screening of Differentially Expressed Proteins in Skin of Chinese Merino Fine Sheep (JunKen Type) by Gender

research [Proteomics-based screening of differentially expressed proteins in skin of Chinese merino fine sheep (JunKen type) of different gender].

1 citations , October 2022 in “PubMed”

Gender affects wool traits in sheep, with males and females showing differences in skin proteins related to wool growth.

research Analysis of LncRNA and mRNA Expression Profiles in Skin Tissues of Super Merino Sheep and Small-Tailed Han Sheep

November 2023

Researchers found genes in sheep that may affect hair growth and wool quality.

research A comparative study of skin transcriptomes and histological observations for black and white hair colors of giant panda

1 citations , November 2022 in “Frontiers in medicine”

The study found that giant pandas have more melanin in black hair follicles than white, with gene expression differences that could affect hair color and skin health.

research LncRNAs regulate the cyclic growth and development of hair follicles in Dorper sheep

July 2023 in “Frontiers in veterinary science”

Certain long non-coding RNAs are important for controlling hair growth cycles in sheep.

Transcriptome Analysis Reveals the Genetic Basis Underlying the Development of Skin Appendages and Immunity in Hedgehog (Atelerix Albiventris)

research Transcriptome analysis reveals the genetic basis underlying the development of skin appendages and immunity in hedgehog (Atelerix albiventris)

2 citations , August 2020 in “Scientific reports”

Genes related to keratin, skin cell differentiation, and immune functions are key in hedgehog skin and spine development.

research Exploring the potential mechanism and molecular targets of Taohong Siwu Decoction against deep vein thrombosis based on network pharmacology and analysis docking

1 citations , January 2024 in “Medicine”

Taohong Siwu Decoction may help treat deep vein thrombosis by reducing inflammation.

Genome Array on Differentially Expressed Genes of Skin Tissue in Cashmere Goat at Early Anagen of Cashmere Growth Cycle Using DNA Microarray

research Genome Array on Differentially Expressed Genes of Skin Tissue in Cashmere Goat at Early Anagen of Cashmere Growth Cycle Using DNA Microarray

4 citations , October 2014 in “Journal of Integrative Agriculture”

Researchers found 24 genes that change significantly and affect cashmere growth in goats; this could help increase cashmere production.

research Analysis of genome DNA methylation at inherited coat-color dilutions of Rex Rabbits

1 citations , January 2020 in “Research Square (Research Square)”

Inherited color dilution in Rex rabbits is linked to DNA methylation changes in hair follicles.

research Comprehensive whole-genome resequencing unveils genetic diversity and selective signatures of the Xiangdong black goat

March 2024 in “Frontiers in genetics”

Xiangdong black goats have moderate genetic diversity, minimal inbreeding, and important genes for reproduction, immunity, and other traits.

Whole Genome Scan and Selection Signatures for Climate Adaptation in Yanbian Cattle

research Whole Genome Scan and Selection Signatures for Climate Adaption in Yanbian Cattle

26 citations , February 2020 in “Frontiers in genetics”

The CORT, FGF5, and CD36 genes are crucial for the cold weather adaptation of Yanbian cattle.

research Identification of Candidate Genes for Min Pig Villi Hair Traits by Genome-Wide Association of Copy Number Variation

3 citations , April 2023 in “Veterinary sciences”

Researchers found genes that may explain why some pigs grow winter hair, which could help breed cold-resistant pigs.

research Genome-wide DNA methylation and transcriptome analyses reveal the key gene for wool type variation in sheep

1 citations , July 2023 in “Journal of Animal Science and Biotechnology”

The SOSTDC1 gene is crucial for determining sheep wool type.

research Genome-Wide Association Studies for Immunoglobulin Concentrations in Colostrum and Serum in Chinese Holstein

September 2020 in “Research Square (Research Square)”

Certain genes influence immunoglobulin levels in Chinese Holstein cows, which can improve calf health.

Exploring the Causal Relationship Between Plasma Proteins and Obstructive Sleep Apnea: A Study Using Genome-Wide Mendelian Randomization, Single-Cell RNA Sequencing Analysis, and Network Pharmacology

research Exploring the Causal Relationship Between Plasma Proteins and Obstructive Sleep Apnea: A Study Using Genome-Wide Mendelian Randomization, Single-Cell RNA Sequencing Analysis, and Network Pharmacology

July 2025

Certain plasma proteins and genes are linked to obstructive sleep apnea, suggesting potential new treatments.

research Genome-based analysis of the genetic pattern of black sheep in Qira sheep

4 citations , February 2025 in “BMC Genomics”

Black wool in Qira sheep is linked to specific gene mutations, especially in the TYRP1 gene.

research A global analysis of CNVs in Chinese indigenous fine-wool sheep populations using whole-genome resequencing

January 2021 in “Research Square (Research Square)”

Chinese fine-wool sheep have genetic variations linked to traits like milk and health, with some genes under strong selection.

research Genome-Wide Association Studies for Immunoglobulins in Colostrum and Serum in Chinese Holstein

July 2020 in “Research Square (Research Square)”

Selective breeding can enhance immunity in dairy cattle.

research Skin transcriptomic and selection signature analyses identify ASIP as a key gene in cattle coat color determination

2 citations , April 2025 in “Frontiers in Genetics”

The ASIP gene is crucial for determining cattle coat color.

research sc-eQTL unveil immunogenetic architecture of polycystic ovary syndrome

January 2026 in “Scientific Reports”

PCOS involves immune and genetic factors, with key roles for T cells and specific genes.

research A global analysis of CNVs in Chinese indigenous fine-wool sheep populations using whole-genome resequencing

November 2019

The study found genetic variations in sheep linked to traits like milk production, growth, and health.

research Genome-wide detection and sequence conservation analysis of long non-coding RNA during hair follicle cycle of yak

September 2020 in “Research Square (Research Square)”

Researchers found that certain RNA sequences play a role in yak hair growth and these sequences are somewhat similar to those in cashmere goats.

research Genome-Wide Association Study for Udder Conformation Traits in Chinese Holstein Cattle

10 citations , September 2022 in “Animals”

Certain genes affect udder shape in Holstein cows, important for health and milk production.

research Cost-effectively dissecting the genetic architecture of complex wool traits in rabbits by low-coverage sequencing

1 citations , March 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

Low-coverage sequencing is a cost-effective way to identify genes related to wool traits in rabbits.

research Pangenome and genome variation analyses of pigs unveil genomic facets for their adaptation and agronomic characteristics

December 2024 in “iMeta”

Pangenome analysis reveals key genes for pig adaptation and traits, aiding genetic improvement.

research Genome Wide Differential Expression Profiles in Nevus Sebaceous Uncovered Low Expression of CDKN2AIP and Construction of a ceRNA Network

March 2022 in “Clinical Cosmetic and Investigational Dermatology”

CDKN2AIP gene is less active in nevus sebaceous, affecting related RNA networks.

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Related Terms

Research

research Using WGCNA (weighted gene co-expression network analysis) to identify the hub genes of skin hair follicle development in fetus stage of Inner Mongolia cashmere goat

research RNA sequence analysis of dermal papilla cells’ regeneration in 3D culture

research [Proteomics-based screening of differentially expressed proteins in skin of Chinese merino fine sheep (JunKen type) of different gender].

research Analysis of LncRNA and mRNA Expression Profiles in Skin Tissues of Super Merino Sheep and Small-Tailed Han Sheep

research A comparative study of skin transcriptomes and histological observations for black and white hair colors of giant panda

research LncRNAs regulate the cyclic growth and development of hair follicles in Dorper sheep

research Transcriptome analysis reveals the genetic basis underlying the development of skin appendages and immunity in hedgehog (Atelerix albiventris)

research Exploring the potential mechanism and molecular targets of Taohong Siwu Decoction against deep vein thrombosis based on network pharmacology and analysis docking

research Genome Array on Differentially Expressed Genes of Skin Tissue in Cashmere Goat at Early Anagen of Cashmere Growth Cycle Using DNA Microarray

research Analysis of genome DNA methylation at inherited coat-color dilutions of Rex Rabbits

research Comprehensive whole-genome resequencing unveils genetic diversity and selective signatures of the Xiangdong black goat

research Whole Genome Scan and Selection Signatures for Climate Adaption in Yanbian Cattle

research Identification of Candidate Genes for Min Pig Villi Hair Traits by Genome-Wide Association of Copy Number Variation

research Genome-wide DNA methylation and transcriptome analyses reveal the key gene for wool type variation in sheep

research Genome-Wide Association Studies for Immunoglobulin Concentrations in Colostrum and Serum in Chinese Holstein

research Exploring the Causal Relationship Between Plasma Proteins and Obstructive Sleep Apnea: A Study Using Genome-Wide Mendelian Randomization, Single-Cell RNA Sequencing Analysis, and Network Pharmacology

research Genome-based analysis of the genetic pattern of black sheep in Qira sheep

research A global analysis of CNVs in Chinese indigenous fine-wool sheep populations using whole-genome resequencing

research Genome-Wide Association Studies for Immunoglobulins in Colostrum and Serum in Chinese Holstein

research Skin transcriptomic and selection signature analyses identify ASIP as a key gene in cattle coat color determination

research sc-eQTL unveil immunogenetic architecture of polycystic ovary syndrome

research A global analysis of CNVs in Chinese indigenous fine-wool sheep populations using whole-genome resequencing

research Genome-wide detection and sequence conservation analysis of long non-coding RNA during hair follicle cycle of yak

research Genome-Wide Association Study for Udder Conformation Traits in Chinese Holstein Cattle

research Cost-effectively dissecting the genetic architecture of complex wool traits in rabbits by low-coverage sequencing

research Pangenome and genome variation analyses of pigs unveil genomic facets for their adaptation and agronomic characteristics

research The idiosyncratic genome of Korean long-tailed chicken as a valuable genetic resource

research Uncovering the genetic architecture and evolutionary roots of androgenetic alopecia in African men

research Genome-Wide Association Studies of Hair Whorl in Pigs

research Genome Wide Differential Expression Profiles in Nevus Sebaceous Uncovered Low Expression of CDKN2AIP and Construction of a ceRNA Network