research Insights learned from L457(3.43)R, an activating mutant of the human lutropin receptor
The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.
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30 / 1000+ results research Valorization of mangosteen (Garcinia mangostana L) waste as green hair dyeing pigment: Effect of mordant and formula optimization
Mangosteen waste can be used as an eco-friendly natural hair dye, producing a lasting reddish color and strengthening hair.
research Anti-keratin Monoclonal Antibodies for Identifying Animal Hair Fibers
Scientists made antibodies to tell cashmere and wool apart, which could improve how we identify animal fibers.
research Nutritional factors and hair loss
Low iron and L-lysine levels can cause hair loss in women, and increasing these nutrients can reduce hair shedding.
research Low Zinc Status Among Palestinian University Students is Related to Hair Loss But Not Diet Score
Appropriate zinc levels may help prevent hair loss in university students.
research Different Requirements for GFRα2-Signaling in Three Populations of Cutaneous Sensory Neurons
GFRα2 is essential for controlling neuron size but not for target innervation in certain sensory neurons.
research Transforming growth factor-β in stem cells and tissue homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
research Overexpression of Smad7 results in severe pathological alterations in multiple epithelial tissues
Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.
research Generation and Characterization of Multipotent Stem Cells from Established Dermal Cultures
Human skin cells can be turned into versatile stem cells, but their ability to do so decreases with repeated use.
research TGFβ and cancer metastasis: an inflammation link
TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.
research Structural insights into SARS-CoV-2 spike protein and its natural mutants found in Mexican population
Mutations in the spike protein affect drug binding and effectiveness.
research Human genetic basis of coronavirus disease 2019
Genetic differences affect COVID-19 severity and treatment development.
research Spontaneous fertility in a male patient with testotoxicosis despite suppression of FSH levels
A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.
research Nosological profile of dermatological diseases in primary health care and dermatology secondary care in Florianópolis (2016–2017)
Primary health care in Florianópolis mostly treated simple skin conditions, while secondary care handled more complex skin diseases.
research Evaluation of SARS-CoV-2 entry, inflammation and new therapeutics in human lung tissue cells
A new method using human lung cells helps find drugs to block and reduce inflammation from SARS-CoV-2.
research Inhibition of autophagy-lysosomal function exacerbates microglial and monocyte lipid metabolism reprograming and dysfunction after brain injury
Blocking autophagy worsens lipid buildup and dysfunction in brain cells after injury.
research COVID-19: How Effective Are the Repurposed Drugs and Novel Agents in Treating the Infection?
Vaccination is the most effective way to reduce COVID-19 transmission.
research Microtechnology-based methods for organoid models
Microtechnology methods improve organoid production for medical research.
research Biochemical and trichological characterization of diffuse alopecia in women
Diffuse alopecia in women may be related to androgens and iron deficiency, and basic hormone and nutrient screening is useful.
research Midazolam Inhibits Hippocampal Long-Term Potentiation and Learning through Dual Central and Peripheral Benzodiazepine Receptor Activation and Neurosteroidogenesis
Midazolam impairs learning and memory by increasing neurosteroids through specific receptor activation.
research Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men
Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
research Increased Scalp Skin and Serum 5a-Reductase Reduced Androgens in a Man Relevant to the Acquired Progressive Kinky Hair Disorder and Developing Androgenetic Alopecia
Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.
research Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology
Spaceflight can harm skin health by altering gene expression, affecting DNA, mitochondria, and skin barriers.
research Hyperadrenocorticism in Ferrets
Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.
research Virilización y enfermedad metabólica en mujer postmenopáusica relacionado a hiperplasia e hipertecosis ovárica
Postmenopausal virilization can be caused by ovarian hyperthecosis, treatable with surgery.
research Lupus Pneumonitis Masquerading As Community Acquired Pneumonia And Pulmonary Tuberculosis: A Case Report
Lupus pneumonitis can be misdiagnosed as pneumonia or tuberculosis, so consider lupus in similar cases for proper treatment.
research European Society of Endocrinology Clinical Practice Guideline: Endocrine work-up in obesity
Test thyroid function in all obese patients and prioritize weight loss for hormonal balance.
research P62 Pre-clinical pharmacological and skin penetration profile of LDE255, a novel and specific Smoothened antagonist
LDE225 is a promising skin-applied treatment for basal cell carcinoma with good skin penetration and effectiveness.
research Absorption Capability of a 645-nm Diode Laser on Swine Soft Tissue Samples: a Preliminary Study in an Ex-Vivo Model Tissue Samples: a Preliminary Study in an Ex-Vivo Mo
A 645-nm diode laser effectively penetrates swine soft tissues, suggesting predictable therapeutic effects.
research LGR5 is a Marker of Poor Prognosis in Glioblastoma and is Required for Survival of Brain Cancer Stem‐Like Cells
High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.