research P62 Pre-clinical pharmacological and skin penetration profile of LDE255, a novel and specific Smoothened antagonist
LDE225 is a promising skin-applied treatment for basal cell carcinoma with good skin penetration and effectiveness.
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750-780 / 1000+ results research Association of mtDNA M/N haplogroups with systemic lupus erythematosus: a case-control study of Han Chinese women
The mtDNA N haplogroup is linked to a higher risk of late-onset lupus and specific symptoms in Han Chinese women.
research New antioxidant lauryl-free herbal shampoo formulation with a Brazilian plant extract
Mangabeira leaf extract is effective for making antioxidant-rich shampoos.
research Prolactin as a candidate sebotrop(h)ic hormone?
Prolactin may influence skin glands and could be a target for treating acne and skin aging.
research Prevention of lipid loss from hair by surface and internal modification
Surface and internal treatments can help prevent hair lipid loss during washing.
research Effect of inhibiting prolactin secretion on secondary hair follicle development in cashmere goats
Inhibiting prolactin reduces hair follicle activation in cashmere goats.
research Comparative study between intralesional injection of prostaglandin F2α alone or combined with corticosteroids in the treatment of alopecia areata
Combining TRA and latanoprost is most effective for treating localized alopecia areata.
research Shampoo compositions
Modern shampoos use a mix of surfactants and other ingredients to clean, reduce irritation, and improve performance.
research Lareb provides update on lamotrigine-associated alopecia
Lamotrigine can cause hair loss in some patients.
research Progressive Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) from a Young Age Due to a Rare Genetic Disorder, Familial Partial Lipodystrophy: A Case Report and Review of the Literature
Recognizing rare causes of MASLD is crucial for effective treatment and preventing complications.
research A novel chitosan-peptide system for cartilage tissue engineering with adipose-derived stromal cells
The chitosan-peptide system helps cartilage regeneration using fat-derived cells.
research Novel Compounds for Hair Repair: Chemical Characterization and In Vitro Analysis of Thiol Cross-Linking Agents
APA is a promising new compound for repairing damaged hair, outperforming Olaplex® in strength and elasticity.
research 17α-Acetoxy-6-bromo-16β-methylpregna-4,6-diene-3,20-dione
A new compound with strong antiandrogenic effects was found, potentially useful for treating conditions like acne and prostate cancer.
research COLOCALIZATION OF ALOPECIA AREATA AND LICHEN PLANUS
Alopecia areata and lichen planus can occur together in children, which is important for diagnosis and treatment.
research New drugs: Agalsidase alfa
Agalsidase alfa helps treat Fabry's disease but needs more research for long-term benefits.
research Commentary: Treatment of lichen planopilaris
Effective treatments for lichen planopilaris are unclear due to inconsistent results and a lack of strong research evidence.
research Multifunctional antibacterial bioactive nanoglass hydrogel for normal and MRSA infected wound repair
The hydrogel speeds up healing of normal and MRSA-infected wounds.
research The Physicochemical, Biopharmaceutical, and In Vitro Efficacy Properties of Freeze-Dried Dexamethasone-Loaded Lipomers
Freeze-dried dexamethasone nanoparticles in a hydrogel are stable and effective for treating alopecia areata.
research Development of Alginate/Carboxymethylcellulose Films Incorporated with Canavalia ensiformis Lectin (ConA) with Angiogenic Properties
The films can help heal wounds by promoting blood vessel growth.
research Nanocarriers for optimizing the balance between interfollicular permeation and follicular uptake of topically applied clobetasol to minimize adverse effects
Nanocapsules can improve clobetasol delivery to hair follicles, reducing side effects.
research Baricitinib as an effective treatment for lichen planopilaris
Baricitinib may effectively treat lichen planopilaris.
research Image 1_Associations between ionomic profile and metabolic abnormalities in a murine model of sodium sulfide induced alopecia areata.tif
Targeting specific metabolic and ionic pathways may improve alopecia areata treatment.
research 522 Gut microbiota is required for the development of alopecia areata
Gut microbiota influences the development of alopecia areata.
research Protective Effect and Mechanism of Placenta Extract on Liver
Placenta extract may protect and improve liver health by reducing stress, inflammation, and cell death, and promoting regeneration.
research Novel recombinant human acid α-glucosidase with optimal glycosylation is significantly better than standard of care enzyme replacement for glycogen clearance in skeletal muscles of GAA knock-out mice
research 382 Environmental pathobiology of frontal fibrosing alopecia (FFA): Does linalool promote FFA development and progression by inducing epithelial hair follicle stem cell damage and MICA expression in the bulge?
Linalool in personal care products may contribute to hair loss by damaging hair follicle stem cells and triggering harmful immune responses.
research Development and Validation of an HPLC-PDA Method for Quantitation of Ten Marker Compounds from Eclipta prostrata (L.) and Evaluation of Their Protein Tyrosine Phosphatase 1B, α-Glucosidase, and Acetylcholinesterase Inhibitory Activities
The method identified and measured ten compounds from Eclipta prostrata, showing significant enzyme inhibitory effects.
research Late presentation of myotonic dystrophy
Myotonic dystrophy should be considered in patients with hair thinning, and genetic counseling is important.
research Interconnected PolymerS TeChnology (IPSTiC): An Effective Approach for the Modulation of 5α-Reductase Activity in Hair Loss Conditions
A new anti-baldness patch effectively treats hair loss by blocking enzymes linked to the condition.
research Green synthesis of silver nanoparticles (AgNPs) using of Laurus nobilis L. leaf extracts and evaluating its antiarthritic activity by in vitro protein denaturation and membrane stabilization assays
Silver nanoparticles from Laurus nobilis leaves may be a new, safer antiarthritic treatment.