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Leflunomide with prednisone is effective and well-tolerated for lupus nephritis when cyclophosphamide can't be used.

Elagolix did not effectively treat polycystic ovary syndrome.

Letrozole may help prevent seizures by reducing certain hormone levels.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Arsenic trioxide effectively treats relapsed acute promyelocytic leukemia with manageable side effects.

Loestrin effectively normalizes testosterone levels and improves PCOS symptoms with minimal side effects.

Proxalutamide improved blood markers related to inflammation, immune response, and clotting in COVID-19 patients, potentially reducing hospitalizations.

The levonorgestrel implant increases free testosterone and lowers SHBG more than DMPA-IM and the copper IUD.

The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.

Proactive physical therapy improved mobility, reduced fatigue, and pain in lupus patients.

New hormonal therapies can help treat advanced prostate cancer but may cause testicular issues.

The combination therapy effectively treats infertility in PCOS without major side effects.

The combination of mitoxantrone, etoposide, and prednisolone is effective for treating relapsed lymphoma with manageable side effects.

Proxalutamide significantly lowered hospitalization rates in women with mild-to-moderate COVID-19.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Oral estradiol works for many transgender women but needs personalized dosing and monitoring.

Estradiol and castration reduced prostate cancer development in rats when applied at early stages, but were ineffective after cancer was established.

Testosterone therapy had limited benefits for a man with depression and suspected low testosterone, highlighting the need for careful diagnosis and treatment planning.

High testosterone levels can harm fertility by disrupting the LIF signaling pathway in the uterus.

Neurosteroids affect prolactin levels in sheep differently depending on stress and pregnancy conditions.

Leflunomide successfully treated a rare skin condition in a liver transplant patient.

The treatment successfully lowered testosterone levels and reduced symptoms.

Chronic GnRHa treatment can help manage endometrial hyperplasia and reduce ovarian androgen excess in PCO patients.

Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.

Loop diuretics may double bone loss in elderly men, finasteride lowers prostate cancer risk but may increase high-grade tumors, abarelix reduces testosterone quickly, and transdermal testosterone offers minimal sexual benefit for women.

Lupeol shows promise for hair growth but needs better absorption and safety testing.

The treatment improved acne, seborrhoea, and hirsutism, with some side effects like spotting and nervousness.

Lenalidomide effectively and safely treats skin symptoms in pediatric lupus, reducing the need for prednisone.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.