3 citations
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December 2023 in “International Journal of Nanomedicine” Repaglinide-loaded liponiosomal hybrids improve blood sugar control and insulin release better than regular Repaglinide.
2 citations
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January 2019 Hormonal contraceptives and therapies regulate organ functions and treat various conditions.
1 citations
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April 2013 in “The FASEB Journal” 3α‐OH‐DHP is essential for reducing nerve activity related to blood pressure control during pregnancy.
29 citations
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May 1975 in “Clinical Endocrinology” Combination therapy significantly reduces testosterone and moderately reduces hair growth in women with hirsutism.
1 citations
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January 2013 in “UNICA IRIS Institutional Research Information System (University of Cagliari)” Hormonal contraceptives may reduce social behavior and sexual motivation by lowering allopregnanolone levels.
30 citations
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January 2009 in “Nuclear Receptor Signaling” Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.
19 citations
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October 2009 in “Bioorganic & Medicinal Chemistry Letters” Thyroid receptor agonists may treat male pattern baldness without harmful side effects.
5 citations
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September 2011 in “Bioorganic & Medicinal Chemistry Letters” Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.
18 citations
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October 2009 in “Endocrinology” Different Hairless isoforms affect Vitamin D receptor activity in hair regulation, with one repressing and the other stimulating it.
11 citations
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January 2015 in “Journal of cellular physiology” HR protein causes abnormal hair cycles by increasing Tgf-β2 and reducing miR-31.
1 citations
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October 2022 in “International journal of endocrinology” Dihydrotestosterone changes some hormone-related gene expressions in rat pituitary glands but doesn't affect the estrous cycle.
22 citations
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April 2010 in “Journal of Cellular Biochemistry” Certain mutations in the hairless protein disrupt its ability to regulate the hair cycle.
74 citations
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September 2006 in “Cell Cycle” The HR protein's role as a repressor is essential for controlling hair growth.
5 citations
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August 2024 in “Cureus” GLP-1 receptor agonists help women with PCOS lose weight and improve health, but more research is needed on long-term effects.
76 citations
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December 1997 in “Fertility and Sterility” Finasteride reduces hair growth better, but spironolactone has more side effects.
January 1993 in “Проблемы Эндокринологии” Spironolactone effectively reduces symptoms of hyperandrogenism but has some side effects.
August 2022 in “Theriogenology” Neurosteroids affect prolactin levels in sheep differently depending on stress and pregnancy conditions.
11 citations
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January 1998 in “Dermatology” Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.
53 citations
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June 1993 in “Proceedings of the National Academy of Sciences of the United States of America” LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.
2 citations
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September 1989 in “PubMed” Canrenone effectively reduced hair growth and testosterone levels in women with excessive hairiness.
20 citations
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August 1987 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Aldactone was more effective in reducing hair growth in women with hirsutism than Diane, despite having less impact on hormone levels.
34 citations
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January 1995 in “The Journal of Clinical Endocrinology and Metabolism”
April 2025 in “Journal of Investigative Dermatology” High LH levels cause hair loss by damaging and aging hair follicles.
14 citations
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April 2013 in “Journal of dermatological science” Hairless protein reduces Msx2 gene activity, affecting hair follicle development.
32 citations
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October 2003 Spironolactone is better than placebo for reducing excessive hair growth in women, but its effectiveness for acne is unclear due to small study sizes.
November 2022 in “Journal of Investigative Dermatology” Growth hormone-releasing hormone (GHRH) boosts hair growth and human scalp hair follicles have their own growth hormone system.
17 citations
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April 1997 in “Archives of dermatology” The document describes a treatment for excessive hair growth in a teenage girl using medication and birth control, but does not report the results.
11 citations
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December 1987 in “Aesthetic Plastic Surgery” The document concludes that the hCG protocol may help in obesity treatment and could be scientifically justified, but more research is needed.
21 citations
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March 1982 in “JAMA” Spironolactone is effective and safe for treating excessive facial hair in women.
1 citations
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June 2025 in “Scientific Reports” Hydroxychloroquine may help treat benign prostatic hyperplasia by reducing inflammation and promoting cell death.