research Multi-omics identifies L-rhamnose as a metabolic regulator that enhances glycolysis to promote hair follicle growth
L-rhamnose may promote hair growth by boosting energy production in cells.
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research PROTAC Degraders of Androgen Receptor‐Integrated Dissolving Microneedles for Androgenetic Alopecia and Recrudescence Treatment via Single Topical Administration
A new hair loss treatment using dissolving microneedles was found to speed up hair growth and was more effective than daily use of common hair growth drugs.
research 18-β-Glycyrrhetinic Acid Promotes Hair Growth by Stimulating the Proliferation of Dermal Papilla Cells and Outer Root Sheath Cells, and Extends the Anagen Phase by Inhibiting 5α-Reductase
Licorice extract helps hair growth and may treat hair loss.
research Monoterpenoid Loliolide Regulates Hair Follicle Inductivity of Human Dermal Papilla Cells by Activating the Akt/ ¥-Catenin Signaling Pathway
Loliolide can boost hair growth by activating specific cell pathways.
research Impact of Laser Therapy on the Quality of Life in Women Living With Polycystic Ovary Syndrome-Associated Hirsutism: An Observational Study
Laser hair removal improves life quality short-term for women with PCOS-related hirsutism.
research The Safety of Local Hormonal Treatment for Vulvovaginal Atrophy in Women With Estrogen Receptor-positive Breast Cancer Who Are on Adjuvant Aromatase Inhibitor Therapy: Meta-analysis
Local hormonal treatment for vulvovaginal atrophy is likely safe for women with estrogen receptor-positive breast cancer on aromatase inhibitors.
research Proxalutamide Improves Inflammatory, Immunologic, and Thrombogenic Markers in Mild-to-Moderate COVID-19 Males and Females: an Exploratory Analysis of a Randomized, Double-Blinded, Placebo-Controlled Trial Early Antiandrogen Therapy (EAT) with Proxalutamide (The EAT-Proxa Biochemical AndroCoV-Trial)
Proxalutamide improved blood markers related to inflammation, immune response, and clotting in COVID-19 patients, potentially reducing hospitalizations.
research BindingDB Entry 50021519: Discovery of (2S)-N-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-3-(6-(4-cyanophenyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)-2-hydroxy-2-methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment.
research Finasteride/spironolactone
research Effects of Microneedle Therapy System(MTS) and Hwangryeonhaedoktang Pharmacopuncture Solution on Hair Growth in an Alopecia Model of C57BL/6N Mouse
Microneedle therapy combined with Hwangryeonhaedoktang solution improved hair growth in mice better than microneedle therapy alone.
research The serum evaluation of sex hormones including DHEAs, DHT, testosterone in oral lichen planus patients
Sex hormones do not cause oral lichen planus.
research Efficacy of Low Level Laser Therapy Combined with Scalp Microneedling using Clobetasol Propionate 0,05% Solution for the Management of Androgenetic Alopecia
Combining low-level laser therapy with scalp microneedling and a clobetasol solution significantly improves androgenetic alopecia.
research Allopregnanolone and Induction of Endogenous Opioid Inhibition of Oxytocin Responses to Immune Stress in Pregnant Rats
Allopregnanolone helps control oxytocin levels during pregnancy to prevent preterm labor.
research A Single Subcutaneous Dose of BMD-1141 Stimulates Hair Regrowth Comparable to Daily, High-Dose Ruxolitinib in a Mouse Model of Alopecia Areata.
BMD-1141 effectively regrows hair in alopecia areata with less frequent dosing than current treatments.
research Reproduction of the human relevant potency threshold (HRPT) for estrogen receptor alpha agonism in an inference performance screen for ICCVAM’s regulatory scientific confidence framework
A new method effectively predicts estrogen-related health effects for early screening.
research Characterization of LHTric-1, a new monospecific monoclonal antibody to the trichocyte keratin Ha1
LHTric-1 is a specific antibody useful for studying hair and nail formation.
research Trends in the prescribing pattern of spironolactone for acne and hidradenitis suppurativa in adolescents
Doctors are prescribing spironolactone more often to treat acne and skin conditions in teenagers, and it seems safe and well-tolerated.
research Testosterone therapy for sexual dysfunction in postmenopausal women
Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.
research Patient Profile and Treatment Characteristics of Adults and Adolescents Prescribed Ritlecitinib for Alopecia Areata in the USA
Ritlecitinib provides new treatment options for diverse alopecia areata patients.
research Balancing metabolic optimization and reproductive safety in Polycystic Ovary Syndrome: a Bayesian-informed framework for GLP-1 receptor agonists
GLP-1 receptor agonists can help manage PCOS metabolism but need careful use before conception.
research Targeting the pre-receptor metabolism of cortisol as a novel therapy in obesity and diabetes
Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.
research Navigating the Intersection of Hormonal Therapy and Acne Management in Trans Youth
Transgender youth on hormone therapy need personalized acne treatments and supportive care.
research Adrenocorticotropic Hormone (ACTH) But Not Alpha-Melanocyte Stimulating Hormone (a-MSH) as a Mediator of Adrenalectomy Induced Hair Growth in Mink
ACTH promotes hair growth in mink, but α-MSH does not.
research Hypothalamic–Pituitary–Thyroid Axis Hormones Stimulate Mitochondrial Function and Biogenesis in Human Hair Follicles
HPT axis hormones boost mitochondrial function and growth in hair follicles, potentially aiding hair health.
research Physical and Functional Interaction between the Vitamin D Receptor and Hairless Corepressor, Two Proteins Required for Hair Cycling
Vitamin D receptor and hairless protein are essential for hair growth.
research Emerging Unconventional Therapies for Alopecia Areata
New therapies for alopecia areata show potential but need more research.
research Hormonal Basis of Male and Female Androgenic Alopecia: Clinical Relevance
Hair loss in men and women is linked to high stress hormone levels and other hormonal imbalances, suggesting treatments should be customized to each person's hormones.
research Identification of xenobiotics interfering with 5 α -reductase (SRD5A2) activity
MK-0773 is a moderate inhibitor of the SRD5A2 enzyme.
research The efficacy of combined therapy with intradermal triamcinolone microinjections and topical minoxidil in female androgenetic alopecia
Combining triamcinolone microinjections with minoxidil improves hair growth in women more than minoxidil alone.
research Antiandrogenic progestins for treatment of signs of androgenisation and hormonal contraception
Certain hormone medications can treat symptoms like acne and unwanted hair, regulate periods, and prevent pregnancy in women and teenage girls.