April 2018 in “Journal of Investigative Dermatology” Cutaneous lupus patients have higher levels of certain immune cells in their blood and skin.
April 2023 in “Journal of Investigative Dermatology” Radiation treatment causes skin fibrosis by increasing certain fibroblast subpopulations, but using a c-Jun inhibitor or fat grafting can reduce this effect.
168 citations
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August 2000 in “American Journal of Pathology” Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.
February 2014 in “PubMed” Modified rat hair follicle stem cells can help create artificial hair follicles, blood vessels, and skin.
March 2026 in “Molecular and Cellular Biomedical Sciences” EH-MSCs may help treat hair loss by reducing inflammation.
August 2020 in “Research Square (Research Square)” Enhanced stem cells can reduce fat buildup in eye tissue for Graves' disease.
Human hair follicle stem cells can be enriched by sticking to type IV collagen.
32 citations
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March 2014 in “PLOS ONE” Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.
2 citations
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June 2025 in “ACS Biomaterials Science & Engineering” Encapsulating cell-free fat extract in GelMA hydrogel improves skin flap survival in mice.
Hair follicle-derived sheets can effectively treat vitiligo by repigmenting skin.
December 2023 in “Medical Times” The MEST method increases cell yield and volume for regenerative medicine but needs more testing.
1 citations
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November 2023 in “Biomaterials advances” Sponges made of soy protein and β-chitin with human cells from hair or fat can speed up healing of chronic wounds.
March 2025 in “Anatomy & Cell Biology” Hair follicle stem cell secretions may help protect brain cells and improve stroke recovery.
488 citations
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July 2021 in “Cell” Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
June 2025 in “Stem Cells and Cloning Advances and Applications” CFx-δ2 from stem cells helps heal burn wounds faster.
42 citations
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February 2017 in “Scientific Reports” Researchers found a way to create cells from stem cells that act like human cells important for hair growth and could be used for hair regeneration treatments.
63 citations
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September 1987 in “Journal of Biological Chemistry” Minoxidil slows fibroblast growth and collagen production, potentially treating keloids, hypertrophic scars, and connective tissue disorders.
July 2023 in “Indian Journal of Animal Health” FGF-5 promotes Cashmere goat hair growth by increasing keratin genes and reducing certain LncRNA and target genes.
3 citations
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February 2023 in “Journal of Investigative Dermatology” Ch55 may help reduce skin scarring and fibrosis.
59 citations
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February 2021 in “Advanced Functional Materials” The silk fibroin-based hydrogel shows promise for treating melanoma and healing infected wounds by killing tumor cells and bacteria, and supporting skin recovery.
4 citations
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June 2021 in “Frontiers in Pharmacology” Bone marrow stem cells and their medium help hair regrowth.
June 2010 in “European Journal of Cancer Supplements” Senescent fibroblasts can help start tumors in normal skin cells.
April 2019 in “Journal of Investigative Dermatology” Targeting immune pathways like JAK/STAT may help treat frontal fibrosing alopecia.
April 2018 in “Journal of Investigative Dermatology” Culturing Dermal Papilla Cells and Hair Follicle Stem Cells in 3D conditions can significantly improve hair regeneration potential.
1 citations
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August 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Extracellular vesicles from amniotic fluid stem cells can improve underdeveloped fetal lungs.
9 citations
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May 2021 in “Immunological Reviews” Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.
January 2021 in “European Journal of Molecular & Clinical Medicine”
March 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” The Enriched-GF method efficiently produces high-yield growth factors for tissue repair.
December 2023 in “International journal of multidisciplinary research and analysis” SH-MSCs gel can effectively treat alopecia by increasing IL-10 and decreasing TNF-α gene expression.
January 2019 in “Social Science Research Network” Hair follicle stem cells prevent melanocyte stem cells from differentiating by controlling retinoic acid levels.