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Transcriptomic Analysis Reveals Candidate Ligand-Receptor Pairs and Signaling Networks Mediating Intercellular Communication between Hair Matrix Cells and Dermal Papilla Cells from Cashmere Goats

research Transcriptomic Analysis Reveals Candidate Ligand-Receptor Pairs and Signaling Networks Mediating Intercellular Communication between Hair Matrix Cells and Dermal Papilla Cells from Cashmere Goats

June 2023 in “Cells”

The research identified key molecules that help hair matrix and dermal papilla cells communicate and influence hair growth in cashmere goats.

research Probing keratinocyte and differentiation specificity of the human K5 promoter in vitro and in transgenic mice.

79 citations , June 1993 in “Molecular and Cellular Biology”

The K5 promoter controls gene expression in skin cells, with specific DNA segments crucial for targeting and regulation.

research Follicle-innervating Aδ-low threshold mechanoreceptors organize through a population-dependent mechanism

August 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

Mouse touch-sensitive nerve cells adjust their connections based on competition with other similar cells.

$Synthesis and Structural Characterization of a New Dinuclear Platinum(III) Complex, [Pt2Cl4(NH3)2{μ-HN=C(O)Bu^t}2]$

research Synthesis and structural characterization of a new dinuclear platinum(III) complex, [Pt₂Cl₄(NH₃)₂{μ-HN=C(O)Bu^t}₂]

2 citations , November 2022 in “Acta crystallographica. Section B, Structural science, crystal engineering and materials./Acta crystallographica. Section B, Structural science, crystal engineering and materials”

A new platinum complex was made and studied, which might help fight cancer better.

research Acitretin Loaded Nanocarrier Gel: Formulation and Exploration of In-vitro Release Kinetics

1 citations , July 2021 in “Current nanomedicine”

The new gel formulation for Acitretin improves topical delivery and reduces oral toxicity.

research HAIR KERATINIZATION IN HEALTH AND DISEASE

22 citations , October 1996 in “Dermatologic clinics”

Understanding intermediate filaments helps explain hair health and related diseases.

research The Localization of Label-Retaining Cells in Mouse Nails

22 citations , October 2007 in “Journal of Investigative Dermatology”

Stem cells in mouse nails are found in the nail matrix and may control nail growth.

research Mediator 1 ablation induces enamel-to-hair lineage conversion through enhancer dynamics

September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

Removing Mediator 1 causes teeth cells to turn into hair cells.

research Nanostructured Lipid Carriers Loaded with an Association of Minoxidil and Latanoprost for Targeted Topical Therapy of Alopecia

January 2021 in “Social Science Research Network”

The new treatment using tiny lipid carriers to deliver minoxidil and latanoprost directly to hair follicles shows promise for alopecia.

research Coordinating Stem Cell Behavior in the Hair Follicle

September 2025 in “Digital Commons - RU (Rockefeller University)”

Nfib in hair follicle stem cells boosts melanocyte stem cell growth and differentiation.

research Linking chromatin dynamics, cell fate plasticity, and tissue homeostasis in adult mouse hair follicle stem cells

3 citations , July 2017 in “Endogenous locus-driven H-Ras G12V expression induces senescence-like phenotype in primary fibroblasts of the Costello syndrome mouse model”

Mouse hair follicle stem cells have a flexible chromatin state that supports skin health and hair growth.

research MOESM1 of A missense variant in the coil1A domain of the keratin 25 gene is associated with the dominant curly hair coat trait (Crd) in horse

January 2017

research Genomic Organization and Amplification of the Human Keratin 15 and Keratin 19 Genes

12 citations , January 2000 in “Biochemical and Biophysical Research Communications”

The study mapped keratin 15 and 19 genes, aiding future genetic disorder research.

research LncRNA NEAT1 and miRNA 101 as potential diagnostic biomarkers in patients with alopecia areata

4 citations , August 2024 in “Non-coding RNA Research”

research Harlequin ichthyosis (ichq): a juvenile lethal mouse mutation with ichthyosiform dermatitis.

27 citations , July 1997 in “PubMed”

The harlequin ichthyosis mouse mutation causes thick skin and early death, resembling a human skin disorder.

research Untargeted hair lipidomics: comprehensive evaluation of the hair-specific lipid signature and considerations for retrospective analysis

4 citations , July 2023 in “Analytical and Bioanalytical Chemistry”

DNA Dioxygenases Tet2/3 Regulate Gene Promoter Accessibility and Chromatin Topology in Lineage-Specific Loci to Control Epithelial Differentiation

research DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation

3 citations , January 2023 in “Science advances”

The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.

research Characterization of a 300 kbp Region of Human DNA Containing the Type II Hair Keratin Gene Domain

77 citations , March 2000 in “Journal of Investigative Dermatology”

The research identified six functional hair keratin genes and four pseudogenes, providing insights into hair formation and gene organization.

research Dramatic Clinical Improvement With Biotin Mega‐Dose Therapy in a Neonate With Holocarboxylase Synthetase Deficiency

2 citations , August 2024 in “Molecular Genetics & Genomic Medicine”

Biotin mega-dose therapy led to dramatic improvement in a newborn with a rare metabolic disorder.

research Characterization of a 190-Kilobase Pair Domain of Human Type I Hair Keratin Genes

74 citations , October 1998 in “Journal of biological chemistry/The Journal of biological chemistry”

The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.

research Folliculotropic mycosis fungoides with central nervous system involvement: Demonstration of tumor clonality in intrafollicular T cells using laser capture microdissection

14 citations , February 2003 in “Journal of the American Academy of Dermatology”

Folliculotropic mycosis fungoides can affect the central nervous system in advanced stages.

research Sequence analyses of Type I and Type II chains in human hair and epithelial keratin intermediate filaments: Promiscuous obligate heterodimers, Type II template for molecule formation and a rationale for heterodimer formation

19 citations , December 2006 in “Journal of Structural Biology”

Type I and Type II keratin chains can form heterodimers despite sequence differences.

research Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration

3 citations , December 2013 in “Journal of Cell Science”

Keratin 79 cells help form and regenerate hair canals.

research Connexin 26 (GJB2) mutations in keratitis–ichthyosis–deafness syndrome presenting with squamous cell carcinoma

11 citations , November 2011 in “The Journal of Dermatology”

Connexin-26 gene mutations may increase cancer risk in KID syndrome patients.

Transcriptome Sequencing Reveals the Expression Profiles of lncRNAs and mRNAs in Goat Skin Tissues With Different Types of Wool Coats

research Transcriptome sequencing reveals the expression profiles of lncRNAs and mRNAs in goat skin tissues with different types of wool coats

1 citations , May 2025 in “Scientific Reports”

The study identified key genes and pathways that influence goat wool quality and growth.

research Differential Expression of Genes Encoding a Cysteine-Rich Keratin Family in the Hair Cuticle

35 citations , September 1994 in “Journal of Investigative Dermatology”

research Premature termination of hair follicle morphogenesis and accelerated hair follicle cycling in Iasi congenital atrichia (fz^ica) mice points to fuzzy as a key element of hair cycle control

20 citations , July 2005 in “Experimental dermatology”

The fuzzy gene is crucial for controlling hair growth cycles.

research CXXC5: A novel regulator and coordinator of TGF-β, BMP and Wnt signaling

28 citations , November 2018 in “Journal of Cellular and Molecular Medicine”

CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.

research Decision letter: Arabidopsis formin 2 regulates cell-to-cell trafficking by capping and stabilizing actin filaments at plasmodesmata

April 2018

Arabidopsis Formin 2 stabilizes actin filaments to aid cell-to-cell trafficking.

research The acyl-CoA binding protein is required for normal epidermal barrier function in mice

31 citations , July 2012 in “Journal of Lipid Research”

ACBP is crucial for healthy skin in mice.

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