October 2023 in “Frontiers in endocrinology” Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.
44 citations
,
February 2012 in “The journal of neuroscience/The Journal of neuroscience” Mutations in the PTPRQ gene cause significant balance issues in mice due to hair bundle defects in the inner ear.
June 1998 in “Pathophysiology” Selenium is crucial for health, but both deficiency and excess can cause problems.
42 citations
,
January 2011 in “Journal of Biomedical Optics” Infrared and Raman imaging can non-destructively analyze hair structure and help diagnose hair conditions.
22 citations
,
September 2011 in “Journal of Investigative Dermatology” TCF/Lef1 is essential for skin barrier function by regulating lipid metabolism.
107 citations
,
August 2012 in “Seminars in Cell & Developmental Biology” The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.
May 2024 in “Food bioscience” Wood sterol may help reduce hair loss caused by a high-fat diet.
December 2023 in “Journal of molecular structure” Hair treatments and dehydration affect hair's lipid and protein behavior, influencing its flexibility and appearance.
72 citations
,
October 1998 in “Baillière's clinical endocrinology and metabolism” Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.
41 citations
,
November 2011 in “The Journal of Dermatology” Some hair loss disorders are caused by genetic mutations affecting hair growth.
17 citations
,
October 2017 in “Scientific reports” Fine wool sheep have more genes for wool quality, while coarse wool sheep have more for skin and muscle traits.
12 citations
,
May 2016 in “British Journal of Dermatology” AGA progression involves increased lipid synthesis, electron transport, and hair follicle miniaturization.
4 citations
,
January 2018 in “Cosmetics” Spin traps like PBN could protect skin from pollution and sunlight in cosmetics but need more research for safe use.
2 citations
,
January 2015 in “Springer eBooks” Early diagnosis and aggressive treatment are crucial for Cicatricial Alopecia, and treatment effectiveness varies among patients.
1 citations
,
October 2017 in “ecancermedicalscience” Breast cancer alters specific molecular structures in hair, which revert after cancer removal.
1 citations
,
February 2013 in “InTech eBooks” Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.
January 2017 in “Springer eBooks” The document concludes that scalp health is influenced by complex factors affecting sebaceous glands, including hormones, aging, and various substances.
September 2025 in “Cosmetics” Lipid content and structure affect water absorption in different hair types.
94 citations
,
September 2014 in “Therapeutic Delivery” Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.
91 citations
,
July 2022 in “Frontiers in Endocrinology” Different PCOS characteristics affect lipid profiles, increasing cardiovascular disease risk, so regular lipid screening is advised.
77 citations
,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
74 citations
,
October 1998 in “Journal of biological chemistry/The Journal of biological chemistry” The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.
69 citations
,
December 2015 in “Journal of Controlled Release” Nanocapsules can improve clobetasol delivery to hair follicles, reducing side effects.
50 citations
,
September 2011 in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids” Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.
49 citations
,
October 2017 in “Nutrients” Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.
39 citations
,
April 2020 in “Clinical, Cosmetic and Investigational Dermatology” Asian hair is generally straight and thick, with unique disorders and properties, and more research is needed to understand it fully.
36 citations
,
May 2025 in “Antioxidants” Lipid peroxidation worsens skin diseases but may help treat cancer.
33 citations
,
February 2021 in “Advanced Pharmaceutical Bulletin” Transdermal drug delivery systems are effective and promising for future use.
28 citations
,
January 2017 in “Critical Reviews in Therapeutic Drug Carrier Systems” Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.
27 citations
,
August 2018 in “Therapeutic Delivery” Nanotechnology could make hair loss treatments more effective and reduce side effects, but more research is needed before it's available.