138 citations
,
August 2020 in “Frontiers in Endocrinology” PCOS affects health and quality of life, with effective treatments available and a need for more research on alternative therapies.
49 citations
,
February 2022 in “Drug Design Development and Therapy” Ritlecitinib shows promise for hair regrowth in alopecia areata patients.
26 citations
,
December 2020 in “International Journal of Molecular Sciences” Treatments for PCOS aim to reduce androgen levels and improve insulin sensitivity to lower cardiometabolic risk.
19 citations
,
June 2021 in “The world journal of men's health” Using anabolic-androgenic steroids can harm men's reproductive health and increase the risk of heart problems and death.
11 citations
,
July 2019 in “International journal of women’s dermatology” Certain skin conditions in women are linked to higher risks of metabolic syndrome and type 2 diabetes due to hormone imbalances.
8 citations
,
January 2021 in “Fermentation” Probiotics and synbiotics might help manage hirsutism by improving insulin resistance.
7 citations
,
May 2022 in “International Journal of Environmental Research and Public Health” Isotretinoin therapy for acne can cause many reversible side effects, mainly mild skin conditions, and patient understanding of these effects can improve treatment adherence.
5 citations
,
January 2017 in “Acta Endocrinologica” High androgen levels in postmenopausal women may suggest an ovarian tumor, and removing it can improve heart and metabolic health.
2 citations
,
September 2021 in “JCPSP. Journal of the College of Physicians & Surgeons Pakistan” Women with PCOS have thicker parafoveal areas in their retinas, but their macular blood vessel density is normal.
November 2025 in “Journal of Clinical Medicine” Baricitinib significantly improved hair regrowth and quality of life in severe alopecia areata patients.
September 2025 in “Medicine” Men with androgenetic alopecia may have a higher risk of heart rhythm problems.
December 2024 in “International Journal of Molecular Sciences” Linoleic acid is important for healthy skin and hair.
53 citations
,
November 2021 in “Molecular Human Reproduction” N-acetylcysteine may help treat uterine and placental issues in PCOS.
35 citations
,
January 2011 in “Journal of Biological Chemistry” sPLA2-X is crucial for normal hair growth and follicle health.
10 citations
,
July 2022 in “Journal of Medicinal Chemistry” Adding a second method to PROTACs could improve cancer treatment.
9 citations
,
June 2016 in “Stem cells” Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.
8 citations
,
July 2023 in “Frontiers in Pharmacology” Cepharanthine shows promise as a COVID-19 treatment.
7 citations
,
September 2024 in “International Journal of Molecular Sciences” PCOS involves high 11-oxygenated androgens and BPA may worsen it, while IH is not inflammatory.
5 citations
,
January 2024 in “Advances in Pharmacological and Pharmaceutical Sciences” Pomegranate shows promise for treating various health issues, but more research is needed.
4 citations
,
December 2021 in “Pharmacological Reports” Metformin is less effective in men with early-onset hair loss.
2 citations
,
May 2025 in “Diagnostics” ATR-FTIR spectroscopy could help monitor alopecia areata treatment response non-invasively.
2 citations
,
April 2023 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” JAK-inhibitors for alopecia areata are generally safe with mostly mild side effects and a low rate of treatment withdrawal.
1 citations
,
December 2023 in “Molecules/Molecules online/Molecules annual” JAK inhibitors show promise for treating various skin diseases.
December 2025 in “International Journal of Molecular Sciences” Exosome-based therapies show promise for treating alopecia areata but need more research.
March 2024 in “Journal of Endocrinological Investigation” Finasteride treatment in rats changed the expression of genes related to psychiatric and neurological functions, and these changes persisted after stopping the drug.
12 citations
,
August 2007 in “Human Molecular Genetics” Lymphotoxin-β is crucial for proper skin development in embryos.
6 citations
,
October 2020 in “Frontiers in cell and developmental biology” WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.
16 citations
,
October 2020 in “Lipids in Health and Disease” Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.
September 1998 in “Journal of the European Academy of Dermatology and Venereology” Autoimmune and inflammatory processes are involved in both scarring and non-scarring types of hair loss.
September 1998 in “Journal of The European Academy of Dermatology and Venereology” Auto-portraits help evaluate scalp hair.