125 citations
,
May 2019 in “Phytomedicine” Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.
116 citations
,
December 2017 in “International Journal of Women's Dermatology” Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.
112 citations
,
July 2008 in “Dermatologic Therapy” Folliculitis decalvans is a rare scalp condition causing scarring hair loss, treated with long-term antibiotics and other medications, but it often comes back and is hard to manage.
112 citations
,
October 2005 in “Mayo Clinic Proceedings” Minoxidil and finasteride can slow hair loss and stimulate regrowth, but won't restore all lost hair or reverse complete baldness.
109 citations
,
October 2007 in “Journal of pineal research” Melatonin helps regulate hair growth and protects the hair follicle from stress.
107 citations
,
August 2012 in “Seminars in Cell & Developmental Biology” The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.
105 citations
,
January 2010 in “Mediators of Inflammation” Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.
104 citations
,
August 2008 in “Clinics in Dermatology” Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.
102 citations
,
February 2008 in “The FASEB Journal” One minoxidil-sensitive potassium channel exists in human hair follicles.
94 citations
,
May 2011 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.
92 citations
,
January 1998 in “Dermatology” Ketoconazole shampoo improves hair growth and reduces oil similarly to minoxidil in male pattern hair loss.
89 citations
,
May 1999 in “Pediatric Dermatology” New antifungal treatments for a children's scalp infection are effective and safe, but it's not decided if they will become the preferred option over the old treatment.
88 citations
,
February 2008 in “Journal of Medicinal Chemistry” Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.
86 citations
,
June 2017 in “Anais Brasileiros de Dermatologia” Antioxidants can benefit skin health but should be used carefully to avoid negative effects.
86 citations
,
October 2005 in “Experimental Dermatology” The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.
86 citations
,
July 1993 in “Drugs” Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.
84 citations
,
April 2013 in “Applied Microbiology and Biotechnology” Mannosylerythritol lipids are good for skin and hair care products.
84 citations
,
July 2008 in “Aaps Pharmscitech” Ethosomes improve finasteride delivery through skin for hair loss treatment.
82 citations
,
December 2015 in “Nanomedicine” Nanoparticle systems make cancer treatment less toxic.
80 citations
,
August 2002 in “Journal of Dermatology” Best hair growth results from combining finasteride and minoxidil.
79 citations
,
January 1982 in “The American Journal of Medicine” Etoposide is effective in treating several cancers, especially small cell lung cancer, with acceptable side effects.
75 citations
,
November 2016 in “Medicines” Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.
71 citations
,
January 2015 in “The Scientific World Journal” Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.
70 citations
,
July 2016 in “Aging” Targeting dermal adipocytes may help combat skin aging.
68 citations
,
December 2014 in “Cell Biochemistry and Function” Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
68 citations
,
November 2012 in “Journal of Investigative Dermatology” Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.
67 citations
,
February 2015 in “Life Sciences” Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.
67 citations
,
January 2012 in “Biological and Pharmaceutical Bulletin” Nanoparticles don't penetrate intact skin but can enter through pores or damaged skin.
67 citations
,
April 2007 in “Journal der Deutschen Dermatologischen Gesellschaft” Shampoos are designed to clean and improve hair and scalp health, with specific ingredients for different hair types and conditions.
66 citations
,
August 2011 in “Parasitology Research” Mint essential oils can kill parasites that cause cystic echinococcosis, with M. pulegium oil being more effective than M. piperita oil.