research Steroid inhibitors of androgen-potentiated actions on skin
Certain hormones can reduce skin oil and hair growth, potentially helping treat acne and excessive hair in women.
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research [Local therapy of androgenetic alopecia with 17 alpha-estradiol. A controlled, randomized double-blind study (author’s transl)].
Hair lotions with 17 alpha-estradiol can reduce hair loss but won't regrow new hair.
research A(1-7) reduces pathologies associated with SLE in MRL-lpr mice
A(1-7) treatment reduces symptoms of lupus in mice.
research Deslorelin treatment of hyperoestrogenism in neutered ferrets (Mustela putorius furo): a case report
Deslorelin effectively treats hair loss in neutered ferrets by reducing hormone levels.
research Therapeutic potential of Ishophloroglucin a from Ishige okamurae in androgenic alopecia: inhibition of 5α-reductase activity and activation of the Wnt/β-catenin signaling pathway in human dermal papilla cells
Ishophloroglucin A from Ishige okamurae may be a natural alternative for treating hair loss by inhibiting 5α-reductase and promoting hair growth.
research Optimization and Transfollicular Delivery of Finasteride-Loaded Proniosomes for Hair Growth Stimulation in C57BL/6Mlac Mice
Finasteride-loaded proniosomes effectively promote hair growth in mice.
research Formulation and Physicochemical Characterization of a Nanostructured Lipid Carrier (NLC) Gel Combining Minoxidil and Finasteride for the Treatment of Alopecia in Prospective Hajj Pilgrims
The NLC gel with Minoxidil and Finasteride effectively treats hair loss in harsh conditions.
research Synthesis, Biological Evaluation and in silico Studies of Novel 5α-aza-Bhomo-3,5-secosteroids as Potential 5-reductase Inhibitors
research The Effects of a Powder of the Fruiting Body of Commercial Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (W.Curt.:Fr.) P.Karts.,] on Hypercholesterolemic Rat Skin, Applied With a Topical Application of Benzo(a)pyrene
Ganoderma lucidum powder may help prevent skin cancer and lower cholesterol.
research Bioactivity of Fractions and Pure Compounds from Jatropha cordata (Ortega) Müll. Arg. Bark Extracts
Compounds from Jatropha cordata bark have significant anti-inflammatory effects and could help with hair loss.
research Additional file 1 of Rejuvenating senescent hair follicles: a novel conjugated linoleic acid based nanovesicle approach to treat androgenic alopecia
research Additional file 1 of Rejuvenating senescent hair follicles: a novel conjugated linoleic acid based nanovesicle approach to treat androgenic alopecia
research PNU 157706, a novel dual type I and II5α-reductase inhibitor
PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.
research Recent Advances in the Chemistry and Pharmacological Activity of New Steroidal Antiandrogens and 5α-Reductase Inhibitors
New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.
research A Narrowed Look Into Plant-Derived Testosterone 5α-Reductase Inhibitors for Androgenetic Alopecia
Plant-based treatments might help with hair loss and have fewer side effects than synthetic drugs.
research Nanoliposomal Co-Delivery of AR-PROTAC and NFKBIZ siRNA for Synergistic Therapy of Androgenetic Alopecia
A new treatment using nanoliposomes can improve hair regrowth in androgenetic alopecia.
research 5α-Reductase Type 2 Regulates Glucocorticoid Action and Metabolic Phenotype in Human Hepatocytes
Manipulating 5α-reductase type 2 can affect liver fat production and glucocorticoid effects.
research The In Vivo and In Vitro Effects of Terminalia bellirica (Gaertn.) Roxb. Fruit Extract on Testosterone-Induced Hair Loss
Terminalia bellirica extract may help promote hair growth and prevent hair loss caused by testosterone.
research A multi-centre, double-blind, randomised, vehicle-controlled study for a quantitative estimation of hair re-growth in male subjects with androgenetic alopecia treated over 6 month with two ethanolic PSK 3841 solutions (2.5% and 5%)
research The Inhibitory Effect of Scutellaria baicalensis Extract and Its Active Compound, Baicalin, on the Translocation of the Androgen Receptor with Implications for Preventing Androgenetic Alopecia
Scutellaria baicalensis extract and baicalin may help prevent hair loss.
research Adipose Tissue‐Derived Exosomes in the Treatment of Lichen Planopilaris: A Case Report
Adipose tissue-derived exosomes may help treat lichen planopilaris and preserve hair.
research FCE 28260, a new 5α-reductase inhibitor: In vitro and in vivo effects
FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.
research Effects of topically applied Platycarya strobilacea S. et Z. extract on hair growth in C57BL/6 mice
Platycarya strobilacea extract significantly improves hair growth and follicle health.
research A COMPREHENSIVE REVIEW OF ORYZA SATIVA AND PSIDIUM GUAJAVA LEAF EXTRACTS IN HERBAL HAIR SERUM FOR IMPROVED HAIR HEALTH
Rice and guava leaf extracts can improve hair and scalp health.
research Therapeutic Potential of Carnosic Acid in Alopecia: A Mechanistic Perspective.
Carnosic acid from rosemary and sage may be a promising natural treatment for hair loss.
research Probing androgen receptor co-factor selectivity profiles: a chemical tool to determine cross-talk between androgen receptor and β-catenin in vivo
PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.
research Double-blind, randomized, placebo-controlled trial of a cream containing theStryphnodendron adstringens(Martius) Coville bark extract for suppressing terminal hair growth
The cream effectively reduces excessive hair growth and related skin issues without side effects.
research The effect of glycyrrhizic acid and aqueous licorice extract on hair growth retardation : in vitro mechanistic and efficacy studies in human
Glycyrrhizic acid and licorice extract can significantly reduce unwanted hair growth.
research Cross-kingdom delivery and putative gene modulation of androgen pathways by plant-derived exosome-like nanoparticles from polygoni multiflori radix promotes hair growth via miRNA cargo
Plant-derived nanoparticles from Polygoni Multiflori Radix promote hair growth better than Minoxidil by affecting androgen pathways.
research Screen steroid 5 alpha-reductase inhibitors in vitro by high performance liquid chromatography
The method is quick and effective for testing steroid 5 alpha-reductase inhibitors.