December 2016 in “University of Birmingham Institutional Research Archive (University of Birmingham)” Glucocorticoids reduce fat production in liver cells, while androgens increase it in females; manipulating certain enzymes can influence these effects.
April 2018 in “Journal of Investigative Dermatology” Hair follicle stem cells can change their role to ensure proper hair development.
2 citations
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January 2008 in “Elsevier eBooks” Humans have limited regenerative abilities, but new evidence shows the adult brain and heart can regenerate, and future treatments may improve this by mimicking stem cell environments.
35 citations
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August 2021 in “npj Regenerative Medicine” Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
44 citations
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September 2011 in “Journal of Pediatric Gastroenterology and Nutrition” NISCH syndrome is a rare genetic disorder affecting skin and liver, with variable symptoms and limited treatment options.
2 citations
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October 2019 in “Nanomedicine” Pharmaceutical care in transplantation faces challenges but has promising future opportunities for better outcomes.
January 2018 in “Stem cells in clinical applications” Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.
January 2012 in “Institutional Repositories DataBase (IRDB)” Cells from skin and lung can help regenerate hair follicles.
1 citations
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October 2016 in “Molecular biology of the cell” The author felt excited and honored to receive the 2016 Early Career Life Scientist Award.
Avicennia marina extract may help treat hair loss naturally.
March 2024 in “Journal of biobased materials and bioenergy” Tea tree oil may help treat scalp alopecia by promoting hair follicle stem cell growth.
September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The Kras mutation changes normal cell signals, leading to disrupted tissue structure and potential cancer.
70 citations
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April 2020 in “Journal of Molecular Cell Biology” Organoid technology helps create mini-organs for studying diseases and testing drugs.
1 citations
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January 2014 in “Assiut Veterinary Medical Journal/Maǧallaẗ Asyūṭ al-ṭibiyyaẗ al-baytariyyaẗ” Emaciated cattle in Aswan have poor health due to parasites and low blood nutrients.
1 citations
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May 2001 in “Pharmacology & Toxicology” Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.
172 citations
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May 2018 in “Nature” Mammalian organs regenerate using stem cells and cell plasticity, but this ability declines with age.
89 citations
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November 2017 in “Journal of Cellular Physiology” The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.
88 citations
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August 2019 in “Nature communications” Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.
136 citations
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April 2013 in “Clinical Cancer Research” The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.
108 citations
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November 1980 in “British Journal of Dermatology” Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.
53 citations
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July 2018 in “Drug design, development and therapy” Janus kinase inhibitors show promise in treating alopecia areata but need better topical formulations.
25 citations
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February 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking SCD1 in the skin with XEN103 shrinks sebaceous glands in mice.
8 citations
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March 2019 in “Open Biology” The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.
8 citations
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February 2014 in “General and Comparative Endocrinology” Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.
4 citations
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October 2018 in “JAMA Dermatology” Ruxolitinib may help treat hair loss and symptoms in patients with chronic graft-versus-host disease.
April 2026 in “Dermatology and Therapy” Personalized hair loss treatments are needed for transgender individuals, but more research is required.
November 2023 in “IntechOpen eBooks” Arsenic exposure from contaminated water severely damages the skin, causing hair loss, pigmentation changes, irritation, and can lead to skin cancer.
May 2023 in “IntechOpen eBooks” More research is needed to understand how testosterone is maintained in adult males.
April 2023 in “Dentistry” Baby teeth stem cells can potentially grow organs and treat diseases.
December 2021 in “Signal transduction and targeted therapy” Increasing sebum production might help reduce fat and improve metabolism.