12 citations
,
February 2018 in “Scientific Reports” Using a drug to activate bone marrow stem cells can help the liver regenerate and function better after major surgery in rats.
53 citations
,
July 2021 in “International Journal of Molecular Sciences” Geranium pyrenaicum extracts show potential for cancer, antiviral, and enzyme inhibition treatments.
20 citations
,
August 2022 in “Archives of Medical Science” The Polish medical societies have redefined metabolic syndrome and recommend lifestyle changes, certain medications, and possibly bariatric surgery for treatment. They also discuss managing related health conditions.
3 citations
,
November 2019 in “Clinical psychopharmacology and neuroscience/Clinical Psychopharmacology and Neuroscience” Valproate can cause both hair loss and curly hair in bipolar disorder patients.
2 citations
,
April 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin D3 is important for hair growth and protecting skin from damage caused by long-term sun exposure.
November 2021 in “International Journal of Trichology” Low PON1 levels may indicate and predict the severity of hair loss.
131 citations
,
September 2017 in “Molecular and Cellular Endocrinology” The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
12 citations
,
November 2022 in “Toxics” EtG in hair can help detect alcohol use but may be inaccurate in people with certain health conditions.
July 2025 in “Journal of Research in Siddha Medicine” Eclipta alba extract is generally safe with mild liver and kidney changes at high doses.
58 citations
,
April 1998 in “Journal of biological chemistry/The Journal of biological chemistry” CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.
5 citations
,
September 2019 in “The Open biomarkers journal” Linoleic acid (Vitamin F) can help protect against the harmful effects of acrylamide.
140 citations
,
April 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” The enzyme 25 Hydroxyvitamin D 1 α-Hydroxylase is essential for healthy skin and recovery after skin damage.
11 citations
,
April 1991 in “Journal of Veterinary Diagnostic Investigation” Shorthorn calves in Missouri experienced photosensitization, causing skin issues and liver damage, but they eventually recovered.
4 citations
,
November 2024 in “International Journal of Dermatology” Testosterone use for muscle growth can cause hair loss in males.
March 2024 in “International journal of molecular sciences” taVNS reduces vitiligo symptoms in mice.
August 2023 in “Medical Hypotheses” Metformin, usually used for diabetes, can also help treat hair loss from alopecia areata due to its ability to reduce inflammation and stimulate new hair growth.
Different types of sun exposure damage skin cells and immune cells, with chronic exposure leading to more severe and lasting damage.
2 citations
,
July 2009 in “Mayo Clinic Proceedings” A 66-year-old woman with skin lesions and other symptoms improved after treatment for porphyria cutanea tarda.
April 2026 in “Dermatology and Therapy” Personalized hair loss treatments are needed for transgender individuals, but more research is required.
115 citations
,
August 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Modulating Cytochrome P450 activity could help develop new skin disease treatments.
62 citations
,
July 2022 in “Science Immunology” TREM2 macrophages and unsaturated lipids contribute to acne inflammation.
48 citations
,
July 1996 in “Human & Experimental Toxicology” Human enzymes can detoxify harmful substances but might also increase their cancer risk.
32 citations
,
January 2022 in “International Journal of Molecular Sciences” Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.
26 citations
,
February 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” An enzyme other than TNAP might be responsible for vitamin B-6 metabolism in the skin.
18 citations
,
March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
12 citations
,
June 2024 in “Nutrients” Natural antioxidants like flavonoids and resveratrol may help prevent low testosterone in aging men.
10 citations
,
October 2012 in “Andrology” Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.
4 citations
,
November 2022 in “Frontiers in endocrinology” The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.
4 citations
,
November 2022 in “Nutrients” Cow placenta extract has strong antioxidant effects and can delay skin aging in mice.
2 citations
,
July 2023 in “Phytotherapy Research” Serenoa repens is mostly safe but has some risks, especially at high doses or when used with other products for over two weeks.