May 2026 in “Skin Appendage Disorders” This systematic review and meta-analysis evaluated the efficacy and safety of lasers and energy-based devices (EBDs) in treating androgenetic alopecia (AGA), involving 3,298 patients across 37 studies. Low-level light therapy (LLLT) showed a mean increase in hair density of 18.56 hairs/cm² and shaft thickness of 10.62 µm compared to sham treatments. Fractional laser monotherapy increased hair density by 102.23 hairs/cm² and thickness by 5.93 µm, while combination protocols with minoxidil, PRP, or growth factors further improved density by 33.6 hairs/cm² and thickness by 11.22 µm. Global photographic improvement rates were 77.2% for fractional laser monotherapy and 95.3% for combination protocols. Adverse events were mild and transient, indicating that LLLT and fractional lasers are effective and safe for AGA, especially when combined with other treatments.
This systematic review and meta-analysis evaluated the efficacy and safety of lasers and energy-based devices (EBDs) in treating androgenetic alopecia (AGA), involving 3,298 patients across 37 studies. Low-level light therapy (LLLT) showed a mean increase in hair density of 18.56 hairs/cm² and shaft thickness of 10.62 µm compared to sham treatments. Fractional laser monotherapy increased hair density by 102.23 hairs/cm² and thickness by 5.93 µm, while combination protocols with minoxidil, PRP, or growth factors resulted in even greater improvements (density +33.6 hairs/cm²; thickness +11.22 µm). Global photographic improvement rates were 77.2% for fractional laser monotherapy and 95.3% for combination protocols. Adverse events were mild and transient, indicating that LLLT and fractional lasers are effective and safe for AGA, with the best results seen when combined with other treatments.
1 citations
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April 2018 in “Lasers in Surgery and Medicine” New treatments and technologies in laser medicine show promise for improving skin conditions, fat reduction, cancer treatment, wound healing, and hair restoration.
June 2024 in “Computational and Structural Biotechnology Journal” Multi-omics techniques help understand the molecular causes of androgenetic alopecia.
62 citations
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July 2018 in “Lasers in Medical Science” LED therapy is safe and shows potential for treating skin conditions and promoting hair growth, but more research is needed.
8 citations
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April 2024 in “Cureus” CO2 lasers are better for severe acne scars, while Er:YAG lasers are gentler with fewer side effects.
1 citations
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June 2024 in “JMIR Dermatology” 675 nm laser therapy effectively improves hair growth and density in AGA patients.
December 2025 in “Journal of Education Health and Sport” LED therapy is safe and effective for improving skin health and appearance.
675 nm laser therapy effectively improves hair growth in Indian patients with androgenetic alopecia.
December 2022 in “Otorhinolaryngology, Head and Neck Pathology.” Photobiomodulation therapy effectively reduces pain after septoplasty.
March 2020 in “Journal of Laser Applications” Photobiomodulation therapy significantly increases hair density and growth for androgenic alopecia, but more research is needed to confirm safety.
60 citations
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November 2020 in “International Journal of Medical Sciences” NIR light therapy may effectively treat eye diseases and improve brain function without side effects.
38 citations
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January 2023 in “International Journal of Medical Sciences” Red-light therapy may slow myopia progression better than traditional treatments.
June 2022 in “World Journal Of Advanced Research and Reviews” Low-level laser therapy can significantly regrow hair in alopecia areata.
September 2018 in “The Medical Journal of Cairo University/The Medical Journal of Cairo University” Polarized light therapy helps hair regrowth in alopecia areata patients.
136 citations
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May 2019 in “Cells” Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.
January 2026 in “MEDS Clinical Medicine” Plum-blossom needle therapy shows promise for treating hair loss but needs more research.
January 2025 in “Advances in Clinical Medicine” Fractional CO2 laser therapy effectively improves skin conditions and recovery when combined with other treatments.
65 citations
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April 2020 in “International Journal of Molecular Sciences” PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.
47 citations
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December 2020 in “Journal of the European Academy of Dermatology and Venereology” The document concludes that understanding and treating hair loss requires recognizing its various types and using appropriate diagnostic tools and treatments.
December 2020 in “Nippon Laser Igakkaishi” Photobiomodulation therapy is beneficial in plastic surgery and dermatology.
December 2024 in “Aesthetic Plastic Surgery” Combining PEMF with PBST is more effective for hair regrowth than PBST alone.
19 citations
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February 2018 in “Lasers in Medical Science” Red light and LED treatments help hair grow by activating a specific cell signaling pathway.
50 citations
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December 2010 in “Dermatologic Surgery” Laser treatment can stimulate hair growth for male pattern hair loss.
4 citations
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September 2021 in “Sensors” LED therapy can safely and effectively regrow eyebrows in people with frontal fibrosing alopecia.
December 2025 in “International Journal for Fundamental and Interdisciplinary Research in Homoeopathy.” A holistic approach combining homeopathy, Xogen therapy, and lifestyle changes may improve hair loss.
April 2025 in “Diagnostics” Managing inflammation and using vitamins can improve PRP therapy for better hair growth.
March 2025 in “Archives of Dermatological Research” Combined microneedling with minoxidil improves hair growth more than minoxidil alone but may cause mild side effects.
February 2025 in “Journal of Nanobiotechnology” A new treatment using microneedles with black phosphorus and laser helps regrow hair effectively and safely.
June 2024 in “Bangladesh Journal of Medicine” Effective alopecia treatment depends on the specific cause and includes medications and procedures.