318 citations
,
January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
31 citations
,
July 2021 in “ImmunoTargets and therapy” Alopecia areata is an incurable autoimmune condition causing hair loss, with research aiming for better treatments.
January 2017 in “Journal of Investigative Dermatology Symposium Proceedings” The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
68 citations
,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” HOXC13 is essential for hair and nail development by regulating Foxn1.
November 2008 in “Journal of the American Academy of Dermatology”
2 citations
,
September 2022 in “Cytotherapy” Fat-derived stem cells show promise for treating skin issues and improving wound healing, but more research is needed to confirm the best way to use them.
48 citations
,
April 2021 in “Journal of the American Academy of Dermatology” Topical corticosteroids are the best initial treatment for children's alopecia areata.
29 citations
,
January 2021 in “Journal of Investigative Dermatology” Fat under the skin releases HGF which helps hair grow and gain color.
12 citations
,
January 2021 in “Journal of Investigative Dermatology” Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.
7 citations
,
September 2023 in “Cancer Treatment Reviews” Managing side effects of endocrine therapy is crucial to improve adherence and survival in breast cancer patients.
January 2026 in “Journal of Biosciences and Medicines” Androgenetic alopecia treatments focus on reducing hair loss by targeting hormones, with new therapies showing promise but needing more research.
January 2025 in “Institutional Repositories DataBase (IRDB)” Maslinic acid from olive extracts promotes hair growth like minoxidil.
3 citations
,
August 2020 in “PubMed” Some natural ingredients like onion juice, rosemary oil, and pumpkin seed oil may help with hair growth and reducing hair loss.
5 citations
,
September 1986 in “Pediatric Dermatology” A family showed a new condition with inherited hair loss and skin changes, possibly due to one genetic disorder.
5 citations
,
October 2012 in “The Journal of Dermatology” Traumatic panniculitis can cause increased hair growth in affected areas.
4 citations
,
August 2004 in “The Journal of Dermatology” Healing psoriatic plaques can cause unexpected hair growth.
10 citations
,
April 2004 in “Journal of the American Academy of Dermatology” Localized hair growth and fat loss may share a common cause in lupus panniculitis.
December 2025 in “Pomeranian Journal of Life Sciences” A miner developed extra shoulder hair due to long-term work pressure and inflammation.
January 2012 in “Case reports in pediatrics” A 16-year-old boy's arm hair grew more after wearing a splint, but it returned to normal in 8 months.
25 citations
,
March 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” A specific gene mutation causes varying hair loss severity in a Pakistani family.
8 citations
,
July 2015 in “International Journal of Dermatology” A new DSG4 gene mutation causes hair defects in a young girl.
5 citations
,
December 2018 in “Annals of plastic surgery” Some burn patients grew extra hair in areas treated with pressure garments or silicone.
5 citations
,
March 1981 in “PubMed” A girl grew extra hair in areas where she had insect bites.
4 citations
,
January 2011 in “Dermatology” A patient grew extra hair on their ears after treatment for testicular cancer, possibly due to hormonal changes or genetics.
50 citations
,
February 2004 in “Genomics” A gene mutation causes lanceolate hair in rats by disrupting hair shaft integrity.
January 2022 in “Dermatology Review” EGFR inhibitors can cause unusual localized hair growth.
4 citations
,
January 2016 in “The Turkish Journal of Pediatrics” A 5-year-old girl got a rare case of extra hair growth on her arm after a henna tattoo.
12 citations
,
January 2014 in “The Pan African medical journal” Minoxidil caused unwanted hair growth in a child, but stopped after stopping treatment.
5 citations
,
September 2015 in “Medical hypotheses” Topical sulfonylurea may reduce excessive hair growth caused by certain medications.
4 citations
,
March 2011 in “European Journal of Dermatology” Trauma can cause fat inflammation and abnormal hair growth.