34 citations
,
December 2007 in “Human Reproduction Update” In vitro bioassays are better than traditional methods for measuring androgen activity but aren't ready for routine use yet.
9 citations
,
June 2002 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” Testosterone therapy can help women with androgen deficiency by improving energy, sex drive, and bone health with few side effects.
August 2017 in “Journal of epidemiological research” Cancer rates are increasing in developed countries, with estrogen, aging, low vitamin D3, and HPV infection as common causes.
6 citations
,
January 2016 in “Evidence-based complementary and alternative medicine” Saw palmetto supplements may reduce prostate cancer cell growth without being toxic.
124 citations
,
September 1992 in “Endocrinology” The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.
82 citations
,
February 1989 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.
70 citations
,
March 2016 in “Urologic Clinics of North America” The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.
65 citations
,
October 1999 in “Journal of The American Academy of Dermatology” Finasteride effectively reduces hair loss by decreasing androgen levels.
36 citations
,
November 1995 in “Clinical endocrinology” Low-dose flutamide helps reduce excessive hair growth and is even more effective with birth control, without bad effects on blood fats.
30 citations
,
June 2000 in “Journal of dermatological science” Human keratinocytes do not naturally respond to androgens.
27 citations
,
April 2013 in “Reviews in endocrine and metabolic disorders” The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.
25 citations
,
April 1988 in “Geburtshilfe und Frauenheilkunde” Treatment balancing hormones stopped hair loss in most women with androgenetic alopecia.
20 citations
,
September 2005 in “Endocrinology” Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.
19 citations
,
June 1999 in “Steroids” Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.
15 citations
,
September 1973 in “PubMed” High androgen levels often cause female hirsutism and infertility.
14 citations
,
January 2016 in “International Journal of Trichology” Many women with hair loss also have thyroid issues, high blood pressure, and low Vitamin D.
14 citations
,
June 2015 in “Toxicology and Industrial Health” Low doses of BPA can increase prostate growth and change hormone levels in adult rats.
12 citations
,
March 2017 in “Medicinal Chemistry Research” Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.
12 citations
,
December 2018 in “Journal of Cosmetic Dermatology” Hair transplant boosts self-esteem and appearance satisfaction, especially in those with high self-esteem.
11 citations
,
December 2019 in “Dermatologic Therapy” Ketoconazole may help regrow hair and increase follicle size, but more research needed.
9 citations
,
October 2012 in “PubMed” Most women in the study lost hair due to stress, fever, childbirth, surgery, or thyroid issues, with low hemoglobin levels also common.
8 citations
,
October 2020 in “Pharmaceutics” Dutasteride-loaded nanoparticles coated with Lauric Acid-Chitosan show promise for treating hair loss due to their controlled release, low toxicity, and potential to stimulate hair growth.
6 citations
,
January 2017 in “Annals of Dermatology” More exercise might link to hair loss, but other factors also matter.
5 citations
,
January 1976 in “Journal of Endocrinology” Oriental men may have lower androgen activity affecting hair growth despite similar testosterone levels to Caucasian men.
4 citations
,
January 2018 in “JBRA assisted reproduction” Orlistat helped reduce weight and testosterone in obese women with PCOS but did not significantly affect other androgens or cholesterol levels.
3 citations
,
January 2022 in “Scientific Reports” A new treatment called SAMiRNA-AR68 increases hair count in people with hair loss, showing similar results to existing treatments but without side effects.
1 citations
,
January 2022 in “Annals of Dermatology” Dutasteride is more effective than finasteride for long-term hair growth in men with androgenic alopecia.
1 citations
,
August 2021 in “Internal Medicine Journal” After severe COVID-19, 71% of patients experienced excessive hair shedding and thinning within 3 months due to factors like low oxygen levels, medication, stress, and autoimmune disease.
1 citations
,
December 2019 in “Current Medicinal Chemistry” Anti-androgen drugs can help reduce OCD symptoms, but more large-scale trials are needed to confirm their effectiveness.
1 citations
,
January 2015 in “Hair therapy & transplantation” Some supplements and hormones can increase hair loss by raising DHT levels.