271 citations
,
May 2019 in “Cells” The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.
223 citations
,
October 2020 in “Microsystems & Nanoengineering” Microtechnology methods improve organoid production for medical research.
183 citations
,
January 1987 in “British Journal of Anaesthesia” Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.
182 citations
,
November 2017 in “Molecular Aspects of Medicine” The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
157 citations
,
May 2021 in “Endocrine Reviews” Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.
146 citations
,
May 2002 in “The American journal of pathology” Cathepsin L is essential for normal hair growth and development.
124 citations
,
December 2016 in “Pharmaceuticals” TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
89 citations
,
November 2017 in “Journal of Cellular Physiology” The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.
86 citations
,
December 2001 in “Experimental dermatology” Mutant mice help researchers understand hair growth and related genetic factors.
71 citations
,
November 2009 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.
60 citations
,
June 1997 in “Drugs & Aging” Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.
58 citations
,
October 2001 in “Dermatologic Clinics” Hair loss can indicate underlying systemic diseases and addressing these can sometimes reverse the hair loss.
57 citations
,
June 2018 in “Nutrients” Celiac disease can cause skin problems that may get better with a gluten-free diet.
53 citations
,
January 2011 in “Diabetes” People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.
49 citations
,
October 2014 in “International Scholarly Research Notices” Eclipta alba has many health benefits and contains compounds with potential for drug development.
48 citations
,
February 2013 in “Molecular and Cellular Endocrinology” The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.
48 citations
,
May 2012 in “Journal of Midwifery & Women's Health” Polycystic Ovary Syndrome is common but often undiagnosed, and early treatment is important to prevent health problems.
47 citations
,
May 2012 in “Applied Water Science” Removing trace elements from drinking water is essential for human safety.
46 citations
,
May 2020 in “Cureus” Zinc is vital for immune health, growth, and preventing diarrhea.
46 citations
,
August 2019 in “Journal of Ethnopharmacology” Eclipta prostrata has many traditional uses and health benefits, but more research is needed to understand how it works and ensure it's safe.
42 citations
,
November 2019 in “Frontiers in Endocrinology” The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.
39 citations
,
January 2019 in “Cells” Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.
39 citations
,
September 2016 in “Expert Opinion on Drug Delivery” New drug delivery methods can make natural compounds more effective and stable.
36 citations
,
January 2012 in “International Journal of Trichology” Losing eyelashes or eyebrows can be a sign of many different health problems and needs a careful approach to treat effectively.
33 citations
,
January 2011 in “Elsevier eBooks” Systemic Lupus Erythematosus has varied symptoms and is hard to diagnose, affecting many body parts and requiring careful clinical judgment.
32 citations
,
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Fatigue is the most common symptom in both ongoing symptomatic COVID-19 and post-COVID-19 syndrome.
24 citations
,
June 2010 in “Clinics in Dermatology” Taking too many vitamin and mineral supplements can cause serious health problems.
23 citations
,
January 2010 in “Journal of Medical Primatology” Hair loss in Rhesus macaques may be caused by a skin allergy-related condition.
21 citations
,
December 2007 in “Primary Care” Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.
20 citations
,
June 2022 in “Molecules” Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.