research Off‐Label Use of Topical Ruxolitinib in Dermatology: A Systematic Literature Review and Current Perspectives
Topical ruxolitinib may help some skin conditions but needs more research for alopecia areata.
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450-480 / 1000+ resultsresearch Lupeol: an updated review utilizing AI-assisted predictive tools for enhanced therapeutic insights into lupeol’s potential for alopecia management
Lupeol shows promise for hair growth but needs better absorption and safety testing.
research LINCS Dataset-Based Repositioning of Dutasteride as an Anti-Neuroinflammation Agent
Dutasteride may help reduce brain inflammation and improve cognition.
research The Role of Interferon-γ in Autoimmune Polyendocrine Syndrome Type 1
Ruxolitinib may effectively treat APS-1 by reducing harmful immune responses.
research Case report: NUDT15 polymorphism and severe azathioprine-induced myelosuppression in a young Chinese female with systematic lupus erythematosus: a case analysis and literature review
Genetic screening for NUDT15 polymorphisms is crucial for patients taking azathioprine, especially in Asians.
research Alopecia Universalis: Never Give Up?
Switching JAK inhibitors can lead to significant hair regrowth in severe alopecia cases.
research The Double-Edged Sword of Epidermal Growth Factor Receptor Inhibitor: Rash as Toxicity and Prognostic Marker
A 50-year-old man undergoing treatment with the epidermal growth factor receptor inhibitor (EGFRI) lapatinib for stage 2 breast carcinoma developed a papulopustular rash, a common side effect of EGFRIs, affecting 50-100% of patients. This rash, part of the 'PRIDE' complex, includes various cutaneous adverse effects such as xerosis and eczema. The patient was treated with doxycycline and hydrocortisone cream, showing significant improvement within a week. Acneiform eruptions, which lack comedones, may serve as a potential marker for therapeutic response to EGFRI drugs, although evidence is inconsistent. The rash typically appears within 1-2 weeks of therapy, peaks at 3-4 weeks, and subsides gradually. Patients are advised on sun protection and gentle skincare to manage symptoms.
research Hair Loss as a Side Effect of Lamotrigine Treatment
Lamotrigine can cause hair loss.
research (13) Tolerance of spironolactone
Most patients tolerated spironolactone for acne and hirsutism despite common side effects like menstrual changes and breast tenderness.
research JAK inhibitor deuruxolitinib shows encouraging hair re-growth in alopecia areata
research Virtual Bioequivalence Assessment of Ritlecitinib Capsules with Incorporation of Observed Clinical Variability Using a Physiologically Based Pharmacokinetic Model
50-mg ritlecitinib capsules are bioequivalent to 100-mg capsules.
research Cushing's syndrome due to pharmacological interaction in a cystic fibrosis patient
A cystic fibrosis patient developed Cushing's syndrome from a drug interaction between itraconazole and budesonide, which improved after stopping the medications.
research Drug Repurposing Patent Applications July–September 2025
New drug uses show promise but need more research.
research Adverse events in patients treated with Jak‐inhibitors for alopecia areata: A systematic review
JAK-inhibitors for alopecia areata are generally safe with mostly mild side effects and a low rate of treatment withdrawal.
research Leuprolide and estrogen versus oral contraceptive pills for the treatment of hirsutism: a prospective randomized study.
Leuprolide plus estrogen is more effective than oral contraceptives for reducing hirsutism.
research Favourable interactions of cytostatic and steroid drugs in treatment of systemic lupus erythematosus.
Combining cytostatic and steroid drugs effectively treats systemic lupus erythematosus.
research New developments in the treatment of systemic lupus erythematosus
New treatments for lupus show promise, but more research is needed, especially for children.
research Spironolactone is an Effective and Well Tolerated Systemic Antiandrogen Therapy for Hirsute Women*
Spironolactone effectively reduces hair growth in women with hirsutism and is generally well-tolerated.
research Treatment of frontal fibrosing alopecia and lichen planopilaris: a systematic review
No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.
research Efficacy and safety of ritlecitinib in adults and adolescents with alopecia areata: a randomised, double-blind, multicentre, phase 2b–3 trial
Ritlecitinib effectively treats alopecia areata and is well-tolerated.
research Alopecia associated with treatment with selective serotonin reuptake inhibitors (SSRIs)
SSRIs can cause hair loss, especially sertraline, with higher risk in women.
research Silent Storm: The Unfolding of Lupus Nephritis in a Young Female Patient
Early diagnosis and aggressive treatment of lupus nephritis can prevent kidney damage and improve outcomes.
research Riboflavin-responsive glutaryl CoA dehydrogenase deficiency
Taking riboflavin and eating less lysine can help some people with a specific genetic disorder avoid brain damage.
research Дослідження ПРОСПЕКТ IV (ПРОСтамол: ПЕрспективи Комбінованої Терапії) у хворих на доброякісну гіперплазію передміхурової залози
"Flosin – Prostamol Uno" effectively manages BPH symptoms with fewer side effects.
research Hair loss disorders (alopecias)
Ritlecitinib is a new treatment for severe hair loss in people 12 and older.
research Synthesis, antiproliferative, acute toxicity and assessment of antiandrogenic activities of some newly synthesized steroidal lactams
research Laser-Assisted Drug Delivery: A Systematic Review of Safety and Adverse Events
Laser-assisted drug delivery is generally safe with mostly mild side effects.
research Comparación de los efectos del D-004, imipramina y sertralina en el modelo de nado forzado en ratones Comparative effects of D-004, Imipramine and Sertraline in the forced swimming test in mice
D-004 shows moderate antidepressant effects but is less effective than Sertraline and Imipramine.
research Baricitinib in the Treatment of Frontal Fibrosing Alopecia: Mid Trial Update
Baricitinib shows promise in improving frontal fibrosing alopecia symptoms.
research Diffuse Hair Loss Induced by Sertraline Use
Sertraline can cause hair loss, which stops after stopping the drug.