June 2025 in “Veterinary Sciences” Oclacitinib effectively treated a diabetic cat's severe skin issues without raising glucose levels, and surgery fixed eyelid fusion.
Tofacitinib significantly improved hair loss and lesions in a patient with overlapping autoimmune disorders.
February 2024 in “Pediatric Dermatology” A 5-year-old girl with a rare genetic disorder, lipoid proteinosis, showed reduced new lesions but persistent scars after avoiding skin trauma.
August 2018 in “Journal of The American Academy of Dermatology” Patients with multiple superficial venous thrombosis are at greater risk for serious complications like cancer and recurrent blood clots.
773 citations
,
August 2017 in “International Journal of Molecular Sciences” The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.
610 citations
,
April 2014 in “Nature Reviews Immunology” The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
522 citations
,
January 2001 in “Cancer investigation” Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.
441 citations
,
May 2008 in “British Journal of Pharmacology” Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.
282 citations
,
April 2007 in “Journal of Agricultural and Food Chemistry” Apple polyphenol, especially oligomeric procyanidins, can reduce fat absorption and lower blood fat levels.
263 citations
,
February 2013 in “Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology” Polymeric nanoparticles show promise for treating skin diseases.
191 citations
,
May 2018 in “British journal of dermatology/British journal of dermatology, Supplement” Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.
170 citations
,
September 2019 in “Evidence-based Complementary and Alternative Medicine” Some medicinal plants can help heal wounds and may lead to new treatments.
152 citations
,
December 2007 in “Gender Medicine” Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.
149 citations
,
June 2002 in “Veterinary record/The veterinary record” Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.
123 citations
,
November 2012 in “Stem cells” MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.
87 citations
,
July 2018 in “Nursing Clinics of North America” PCOS is a common hormonal disorder in women, marked by symptoms like hair growth and menstrual issues, and requires personalized treatment.
86 citations
,
January 2019 in “Frontiers in Immunology” The document concludes that diagnosing and treating Human African Trypanosomiasis is challenging, but new treatments like fexinidazole are promising.
85 citations
,
July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
77 citations
,
July 2020 in “Journal of the European Academy of Dermatology and Venereology” Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.
75 citations
,
June 2019 in “International Journal of Molecular Sciences” Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.
69 citations
,
January 2020 in “Veterinary World” Ringworm in pets is influenced by fungi type, immune status, and stress hormones.
69 citations
,
June 2017 in “Experimental Biology and Medicine” Advanced human skin models improve drug development and could replace animal testing.
69 citations
,
December 2016 in “Facial plastic surgery” Different types of facial fat affect aging and treatment outcomes; more research is needed to enhance anti-aging procedures.
68 citations
,
July 2011 in “Journal of Biochemistry/The journal of biochemistry” New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.
68 citations
,
June 2005 in “Expert Opinion on Therapeutic Targets” Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.
67 citations
,
January 2022 in “Theranostics” Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
65 citations
,
June 2021 in “Frontiers in Pharmacology” Targeting abnormal lung fluid metabolism could reduce COVID-19 deaths and ventilator use.
65 citations
,
February 2017 in “Pflügers Archiv - European Journal of Physiology” Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.
61 citations
,
January 2018 in “Cosmetics” Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.
59 citations
,
March 2020 in “Journal of Biomedical Science” Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.