A high neutrophil-to-lymphocyte ratio may predict poor response to hair loss treatment.
August 2023 in “Journal of The American Academy of Dermatology” Early treatment is key for permanent hair loss disorders, with options ranging from medications and phototherapy to immunomodulators and antibiotics, depending on severity and type.
July 2025 in “Journal of Investigative Dermatology” Scarring alopecia involves increased immune cells and specific gene changes near damaged hair follicles.
November 2023 in “Journal of Investigative Dermatology” Different types of hair loss have unique cellular changes, suggesting new treatment targets.
22 citations
,
January 2017 in “Skin appendage disorders” The conclusion is that primary scarring alopecia is a complex condition that requires early and accurate diagnosis for effective treatment.
Tumid lupus erythematosus can cause non-scarring hair loss on the scalp and requires careful diagnosis.
Multiphoton microscopy can effectively distinguish between scarring and non-scarring alopecia.
332 citations
,
June 1994 in “Archives of Dermatology” Postmenopausal frontal fibrosing alopecia may be a unique condition linked to postmenopausal changes.
1 citations
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June 2012 in “Actas Dermo-Sifiliográficas” Early and aggressive treatment of scarring alopecia is important to prevent further hair follicle damage.
January 2024 in “Pan African Medical Journal” Non-scarring hair loss is common in lupus patients and can be diagnosed with specific hair and tissue tests.
30 citations
,
October 2013 in “Lupus” Hair loss in lupus is different from hair loss in alopecia areata and may indicate lupus activity.
3 citations
,
August 2024 in “Skin Research and Technology” LC-OCT can help identify lupus-related scarring hair loss by spotting unique features.
1 citations
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July 2021 in “Curēus” A child had a rare case of scarring hair loss with skin disease, which is hard to treat and stressful.
December 2025 in “Cureus” Localized dystrophic epidermolysis bullosa (DEB) can lead to scarring alopecia, highlighting the need to recognize and address this complication.
April 2025 in “Düzce Tıp Fakültesi Dergisi” Vitamin D deficiency is common in children with non-scarring alopecia, and managing it may help treatment.
170 citations
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December 2009 in “Histopathology” The conclusion is that accurate diagnosis of different types of hair loss requires good teamwork between skin doctors and lab experts.
15 citations
,
September 2014 in “Journal of The American Academy of Dermatology” Seven patients were misdiagnosed with discoid lupus instead of lichen planopilaris due to similar symptoms, showing the need for careful diagnosis in scarring hair loss conditions.
1 citations
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December 2023 in “JAAD International” Mast cells may significantly contribute to central centrifugal cicatricial alopecia.
January 2025 in “Indian Journal of Dermatology” Frontal fibrosing alopecia is a challenging hair loss condition with no known cause or definitive treatment.
January 2024 in “Revista Dermatológica Centro Uraga” Frontal fibrosing alopecia is increasingly affecting men, causing hair loss around the hairline and possibly other areas.
November 2018 in “Skin appendage disorders” The document concludes that a woman has both Frontal Fibrosing Alopecia and Lichen Simplex Chronicus, a previously unreported combination of conditions.
28 citations
,
July 2002 in “Australasian Journal of Dermatology” Lupus can look like hair loss from alopecia areata but needs different treatment.
July 2023 in “Journal of Clinical Medicine” The document concludes that understanding hair follicle histology and the hair cycle is crucial for diagnosing alopecia.
September 1998 in “Journal of the European Academy of Dermatology and Venereology” Autoimmune and inflammatory processes are involved in both scarring and non-scarring types of hair loss.
6 citations
,
January 2019 in “Medical Hypotheses” Frontal Fibrosing Alopecia might be an autoimmune disease.
1 citations
,
October 2018 in “InTech eBooks” The document concludes that treatments for cicatricial alopecia are not well-supported by evidence, but hair transplantation shows more predictable and satisfactory results.
42 citations
,
January 2008 in “SKINmed/Skinmed” The article explains how to diagnose and manage certain types of scarring hair loss.
16 citations
,
February 2010 in “Journal of the European Academy of Dermatology and Venereology” Fibrosing alopecia in a pattern distribution is a unique hair loss condition that may respond to antiandrogen therapy.
14 citations
,
January 2014 in “Indian Journal of Dermatology Venereology and Leprology” Frontal fibrosing alopecia can affect men's beards and leads to permanent hair loss.
12 citations
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June 2015 in “Dermatology Reports” Middle-aged women in Iran are most affected by primary cicatricial alopecia, especially discoid lupus erythematous.