research Pathogenesis and management of TRPV3-related Olmsted syndrome
EGFR and mTOR inhibitors may help manage Olmsted syndrome symptoms.
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900-930 / 1000+ results research Effect of 5-alpha reductase inhibitors in animal models of Parkinson’s disease
5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.
research Stem-cell therapy in dermatology – Challenges and opportunities
Stem-cell therapy shows promise for skin conditions but needs more research.
research An Insight into Biodegradable Polymers and their Biomedical Applications for Wound Healing
Biodegradable polymers help wounds heal faster.
research Pharmacotherapy for Keloids and Hypertrophic Scars
Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.
research Functionalization of Alkenes with Difluoromethyl Nitrile Oxide to Access the Difluoromethylated Derivatives
A new method efficiently modifies alkenes to create useful medicinal compounds.
research EBS in Children with De Novo Pathogenic Variants Disturbing Krt14
Three specific genetic variants cause severe skin issues in children with EBS, highlighting the need for early genetic screening.
research Transcranial photobiomodulation for brain diseases: review of animal and human studies including mechanisms and emerging trends
Light therapy on the brain shows promise for treating brain diseases and improving brain function.
research The Multisystem Impact of Long COVID: A Comprehensive Review
Long COVID causes a wide range of long-lasting symptoms that change over time and are hard to diagnose and treat.
research Effectiveness of a Novel Compound HAIR & SCALP COMPLEX on Hair Follicle Regeneration
HAIR & SCALP COMPLEX may help treat hair loss by stimulating hair growth and restarting the hair cycle.
research POST-FINASTERIDE SYNDROME AND POST-SSRI SEXUAL DYSFUNCTION: TWO CLINICAL CONDITIONS APPARENTLY DISTANT, BUT VERY CLOSE
Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.
research Development of a novel in vitro strategy to understand the impact of shaving on skin health: combining tape strip exfoliation and human skin equivalent technology
The method effectively mimics shaving damage on skin for testing skincare products.
research Does Nirmatrelvir/Ritonavir Influence the Immune Response against SARS-CoV-2, Independently from Rebound?
Nirmatrelvir/Ritonavir treatment may lead to a weaker immune response to COVID-19, but doesn't affect the chance of rebound.
research The Progress in Bioprinting and Its Potential Impact on Health-Related Quality of Life
Bioprinting could greatly improve health outcomes but faces challenges like material choice and ensuring long-term survival of printed tissues.
research Orchestration of Mesenchymal Stem/Stromal Cells and Inflammation During Wound Healing
Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.
research N,N-Dimethylglycine Sodium Salt Exerts Marked Anti-Inflammatory Effects in Various Dermatitis Models and Activates Human Epidermal Keratinocytes by Increasing Proliferation, Migration, and Growth Factor Release
N,N-Dimethylglycine Sodium Salt helps reduce skin inflammation and improves skin cell growth and healing.
research Efficacy and safety of proxalutamide (GT0918) in severe or critically ill patients with COVID-19: study protocol for a prospective, open-label, single-arm, single-center exploratory trial
The trial will test if proxalutamide is safe and effective in reducing death in severe COVID-19 patients.
research Effect of Neurosteroids on Basal and Stress-Induced Oxytocin Secretion in Luteal-Phase and Pregnant Sheep
Neurosteroids help regulate oxytocin levels, especially during stress and pregnancy, to protect against premature labor.
research Insights into the Scenario of SARS-CoV-2 Infection in Male Reproductive Toxicity
COVID-19 may harm male reproductive health and lower testosterone levels, potentially affecting fertility and causing erectile dysfunction. More research is needed.
research Which is the ideal JAK inhibitor for alopecia areata – Baricitinib, tofacitinib, ritlecitinib or ifidancitinib - Revisiting the immunomechanisms of the JAK pathway
No single ideal JAK inhibitor for alopecia areata has been determined; JAK3 inhibitors may be promising with fewer side effects.
research CXCL12 inhibits hair growth through CXCR4
CXCL12 protein slows down hair growth through its receptor CXCR4. Blocking this can potentially increase hair growth.
research In This Issue
Hedgehog signaling is crucial for hair development, cadherins affect cell adhesion, neutrophils play a role in skin lesions, and BP230 autoantibodies impact skin stability.
research Aberrant Activation of the Hedgehog Pathway in Cutaneous Melanoma: Therapeutic Potential of Pharmacological Inhibitors
Hedgehog pathway inhibitors could be effective in treating melanoma.
research Hypoxic Preconditioned Nanofat at 1% O2 for 24 h Loses Its Regenerative In Vivo Vascularization Capacity
Hypoxic preconditioning reduces nanofat's ability to form blood vessels.
research The Skin Microenvironment: A Dynamic Regulator of Hair Follicle Development, Cycling and Disease
The skin microenvironment significantly affects hair growth and loss, offering potential treatment avenues.
research CXCL12 Drives Reversible Fibroimmune Remodeling in Androgenetic Alopecia Revealed by Single-Cell RNA Sequencing
Blocking CXCL12 can reverse hair loss and fibrosis in androgenetic alopecia.
research Progress in Research and Prospects for Application of Precision Gene-Editing Technology Based on CRISPR–Cas9 in the Genetic Improvement of Sheep and Goats
CRISPR/Cas9 gene-editing shows promise for improving sheep and goat breeding but faces challenges with efficiency and accuracy.
research Identification of Potential miRNA–mRNA Regulatory Network Associated with Growth and Development of Hair Follicles in Forest Musk Deer
The research found genes and miRNAs that may control hair growth in Forest Musk Deer.
research Hair Growth Promotion and Anti-Hair Loss Effects of By-Products Arabica Coffee Pulp Extracts Using Supercritical Fluid Extraction
Arabica coffee pulp extract may help prevent hair loss and promote hair growth.
research https://researchopenworld.com/genetics-of-hidradenitis-suppurativa/#
Hidradenitis Suppurativa has genetic links, with certain gene mutations more common in patients and a third of cases having a family history.