research HtrA1L364P leads to cognitive dysfunction and vascular destruction through TGF‐β/Smad signaling pathway in CARASIL model mice
The HtrA1L364P mutation causes brain dysfunction and blood vessel damage.
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870-900 / 1000+ resultsresearch Integration of Colorimetric Sensing Dyes and Multi‐Substrate Arrays for Food Quality and Safety Monitoring: Design, Optimization, and Analysis
Combining advanced sensors with portable devices could enhance on-site food safety monitoring.
research Correlation between MRI findings of pituitary gland and prolactin level among hyperprolactinemia adult female Saudi patients in rural areas: A retrospective multicentric study
Pituitary imaging is recommended for hyperprolactinemia due to common pituitary issues.
research Exploring the Versatility of Microemulsions in Cutaneous Drug Delivery: Opportunities and Challenges
Microemulsions could improve skin drug delivery but face challenges like complex creation and potential toxicity.
research Outbreak of recombinant lumpy skin disease virus in yaks: high mortality and systemic pathogenesis in Qinghai-Tibet Plateau yak herds
A severe virus outbreak in yaks on the Qinghai-Tibet Plateau caused high death rates and requires targeted control measures.
research Protein Immobilization on Bacterial Cellulose for Biomedical Application
Bacterial cellulose is a promising material for biomedical uses but needs improvements in antimicrobial properties and degradation rate.
research Preparation, solubility, and anti-inflammatory effects of a complex of diphenylcyclopropenone/β-cyclodextrin derivatives as the treatment of alopecia areata
The DPCP/HPβCD complex improves solubility and anti-inflammatory effects for alopecia areata treatment.
research Dose-Response Relationship of Therapeutic Oxygen: More Is Not Necessarily Better and May Be Inferior to No Supplemental Oxygen – Part 2: Implications and Consequences
More oxygen isn't always better and can sometimes be worse.
research eLife assessment: Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2
Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.
research Harmonic Vibrational Frequency Simulation of Pharmaceutical Molecules via a Novel Multi-Molecular Fragment Interception Method
The new method provides more accurate vibrational frequencies for drug molecules than traditional models.
research Nanotechnological Interventions and Mechanistic Insights into Wound-Healing Events
Nanotechnology can improve wound healing by enhancing treatments and dressings.
research Progress in Gelatin as Biomaterial for Tissue Engineering
Gelatin shows promise for future medical uses due to its safety and versatility, despite some challenges.
research Challenges in the Physical Characterization of Lipid Nanoparticles
Characterizing lipid nanoparticles is challenging due to issues with sensitivity, reproducibility, and reliability.
research Hydrogel-Based Skin Regeneration
Hydrogels show promise for improving skin wound healing.
research Recent Advances in the Structural Design of Photosensitive Agent Formulations Using “Soft” Colloidal Nanocarriers
New nanocarriers improve drug delivery for disease treatment.
research Effective treatment of intractable diseases using nanoparticles to interfere with vascular supply and angiogenic process
Nanoparticles can effectively treat diseases by modifying blood vessel growth.
research Recent Advances in the Use of Cubosomes as Drug Carriers with Special Emphasis on Topical Applications
Cubosomes improve drug delivery for skin and eye diseases by enhancing adhesion, retention, and release.
research Current Biomedical Applications of 3D-Printed Hydrogels
3D-printed hydrogels show promise in medicine but face challenges in resolution, cell viability, cost, and regulations.
research Current and prospective strategies for advancing the targeted delivery of CRISPR/Cas system via extracellular vesicles
Engineered extracellular vesicles could improve CRISPR/Cas delivery, making gene editing safer and more effective.
research Alginate-Based Cryogels for Combined Chemo/Photothermal Antibacterial Therapy and Rapid Hemostasis
SEF cryogels effectively kill bacteria, stop bleeding, and speed up wound healing.
research Biological properties of polycaprolactone and barium titanate composite in biomedical applications
Polycaprolactone and barium titanate composites show promise for use in biomedical applications.
research Responsive Microneedles as a New Platform for Precision Immunotherapy
Microneedles can precisely deliver cancer treatments with fewer side effects.
research Engineering Cell Surfaces with Polyelectrolyte Materials for Translational Applications
Polyelectrolytes can improve cell surfaces for better medical applications.
research Droplet-Based Microfluidics as a Platform to Design Food-Grade Delivery Systems Based on the Entrapped Compound Type
Microfluidics can create precise, efficient delivery systems for food and cosmetics, but scaling up is challenging.
research Modulation of Macrophage Function by Bioactive Wound Dressings with an Emphasis on Extracellular Matrix-Based Scaffolds and Nanofibrous Composites
Bioactive wound dressings can improve healing by promoting beneficial macrophage activity.
research Semifluorinated Alkanes as New Drug Carriers—An Overview of Potential Medical and Clinical Applications
Semifluorinated alkanes are promising for delivering drugs in various medical applications.
research Injectable Biomimetic Gels for Biomedical Applications
Injectable biomimetic gels can help heal tissues and deliver drugs but need improvements in strength and delivery.
research Biomaterials Mimicking Mechanobiology: A Specific Design for a Specific Biological Application
Polymers can be designed to mimic natural cell environments for medical uses.
research Native and engineered extracellular vesicles for wound healing
Extracellular vesicles show promise for wound healing, but more research is needed to improve their stability and production.
research Application of stem cells in regeneration medicine
Stem cells and their exosomes show promise for repairing tissues and healing wounds when delivered effectively, but more research is needed on their tracking and optimal use.