research Increased androgen receptor messenger RNA in frontal-parietal hair follicles of women with androgenetic alopecia
Women with hair loss have more androgen receptors in certain hair follicles.
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research Male pattern hair loss: prevention rather than regrowth
Preventing hair loss is more effective than regrowth; oral finasteride is a realistic option.
research Combined oral contraceptives promote androgen receptor and oestrogen receptor alpha upregulation in the female prostate (Skene’s paraurethral glands) of adult gerbils (Meriones unguiculatus)
Birth control pills increase certain receptor activities in female gerbil prostate glands and can lead to prostate changes.
research Novel Missense Mutation in the P-Box of Androgen Receptor in a Patient with Androgen Insensitivity Syndrome
A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.
research Concomitant immobilization of androgen receptors and 5α- reductase in androgenic alopecia
Anagen grow may effectively treat hair loss by blocking testosterone and reducing enzyme activity.
research Sex Hormones and Related Compounds, Including Hormonal Contraceptives
The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.
research A pilot study on the sexual side effects of finasteride as related to hand preference for men undergoing treatment of male pattern baldness
Left-handed men experience more sexual side effects from finasteride treatment.
research Effects of Finasteride (MK-906), a 5α-Reductase Inhibitor, on Circulating Androgens in Male Volunteers*
Finasteride safely lowers DHT levels without affecting testosterone.
research 5α-Reductase type 2 gene variant associations with prostate cancer risk, circulating hormone levels and androgenetic alopecia
A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.
research Are sex discordant outcomes in COVID-19 related to sex hormones?
Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.
research Vitamin D receptor polymorphisms and the polycystic ovary syndrome: A systematic review
The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.
research Key targets of hormonal treatment of prostate cancer. Part 2: the androgen receptor and 5α-reductase
Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.
research Aging in the Male Face: Intrinsic and Extrinsic Factors
Male faces age with more wrinkles and hair loss, influenced by both body changes and environmental factors.
research Ovarian hormones and adrenal androgens during a woman's life span
Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.
research Androgen receptors are only present in mesenchyme-derived dermal papilla cells of red deer (Cervus elaphus) neck follicles when raised androgens induce a mane in the breeding season
Red deer only have androgen receptors in neck hair cells for mane growth during breeding season.
research Finasteride and Erectile Dysfunction in Patients with Benign Prostatic Hyperplasia or Male Androgenetic Alopecia
Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.
research Hirsutism, postpartum telogen effluvium, and male pattern alopecia
Hormonal changes during and after pregnancy can cause hair growth changes and hair loss, with treatments available for some conditions.
research Male Androgenetic Alopecia and Cardiovascular Risk Factors: A Case-Control Study
Balding men have higher heart disease risk.
research The Impact of 5α-Reductase Inhibitor Use for Male Pattern Hair Loss on Men’s Health
Hair loss drugs may cause sexual issues and infertility in men.
research Urinary steroids in men with male-pattern alopecia
Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.
research Male fertility and skin diseases
Some skin diseases and their treatments can negatively affect male fertility.
research Polymorphic CAG repeat numbers in the androgen receptor gene of female pattern hair loss patients
Longer CAG repeats in gene linked to more severe hair loss in females.
research Association between male pattern baldness and prostate disease: A meta-analysis
Men with male pattern baldness have a higher risk of aggressive prostate cancer and benign prostatic hyperplasia.
research Maintenance of optimised hair growth from viable terminal scalp hair follicles at baseline with oral finasteride in male pattern hair loss and first evidence of a “drug dependency” and a post-finasteride “rebound effect”.
Finasteride helps hair growth but stopping it causes faster hair loss.
research The association of male pattern baldness and risk of cancer and high-grade disease among men presenting for prostate biopsy
Men with more advanced male pattern baldness have a higher risk of prostate cancer and more severe disease.
research Probing androgen receptor co-factor selectivity profiles: a chemical tool to determine cross-talk between androgen receptor and β-catenin in vivo
PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.
research Ferulic acid promotes hair growth via estrogen receptor alpha activation in cultured human dermal papilla cells
Ferulic acid may help hair grow by activating certain receptors in cells.
research Androgen receptor gene polymorphism and biological age markers in men
AR gene variations don't affect aging markers in men.
research If Women Just had Their Hormones Back the Way they Were!
Balancing hormones is crucial for women's health and may require hormone therapy.
research Glucocorticoid Receptor Antagonism Improves Glucose Metabolism in a Mouse Model of Polycystic Ovary Syndrome
Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.