75 citations
,
November 2007 in “Clinical endocrinology” Certain medications including flutamide, spironolactone, and others effectively reduce excessive hair growth in women, especially when combined with lifestyle changes.
71 citations
,
January 2014 in “Journal of Proteome Research” Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.
55 citations
,
March 2000 in “American journal of clinical dermatology” Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.
51 citations
,
November 2011 in “Reproductive Biology and Endocrinology” About 13% of women had idiopathic hirsutism and 8.5% had polycystic ovary syndrome in a group of Iranian women.
47 citations
,
August 2014 in “The Journal of Clinical Endocrinology and Metabolism” The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.
45 citations
,
March 2015 in “Clinical Endocrinology” Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.
43 citations
,
April 2017 in “Experimental Dermatology” Female pattern hair loss has unclear causes, possibly involving genetics, hormones, and environment, and needs better treatments.
43 citations
,
July 2012 in “Molecular human reproduction” Certain metabolites are lower in women with PCOS and could be potential markers for the condition.
43 citations
,
May 1988 in “British Journal of Dermatology” Patients with acanthosis nigricans often have insulin resistance and signs of increased male hormones, but treatment targeting these male hormones is generally ineffective.
38 citations
,
July 2012 in “international journal of endocrinology and metabolism” Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.
37 citations
,
February 2017 in “Anais Brasileiros De Dermatologia” AGA more common in men, increases with age, linked to family history, hypertension, dyslipidemia, and smoking.
31 citations
,
January 1995 in “The American journal of medicine” Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.
29 citations
,
March 2017 in “International Journal of Women's Dermatology” Hormone therapies like birth control pills and spironolactone are safe and effective for treating women's adult acne.
24 citations
,
September 2001 in “Journal of The American Academy of Dermatology” Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.
21 citations
,
May 2021 in “Patient education and counseling” Managing PCOS is hard because it varies a lot, treatments are limited, and there's a lot of false information online.
19 citations
,
October 2024 in “BMC Medical Informatics and Decision Making” AI can improve early diagnosis and classification of PCOS, aiding in prevention of related health issues.
17 citations
,
October 2003 in “Brazilian Journal of Medical and Biological Research” The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.
16 citations
,
November 2018 in “Singapore Medical Journal” Primary care for PCOS focuses on lifestyle changes, medication based on symptoms, and mental health, with diabetes screening and specialist referral for severe cases.
16 citations
,
December 2007 in “Expert Review of Pharmacoeconomics & Outcomes Research” PCOS lowers quality of life, causing issues like obesity, infertility, and menstrual problems.
11 citations
,
November 2013 in “Skin Pharmacology and Physiology” Azelaic Acid is effective and safe for treating adult female acne, with few side effects.
11 citations
,
May 2009 in “Medical Hypotheses” Male pattern baldness is an unintended side effect of the body's use of androgens for muscle growth, especially in those genetically prone to it.
11 citations
,
February 2008 in “British journal of nursing” Idiopathic hirsutism causes excessive hair growth in women, can be treated with medication and hair removal, but cannot be fully reversed.
10 citations
,
January 2004 in “KARGER eBooks” Diagnosing PCOS in teenage girls is tricky and requires careful evaluation and management.
9 citations
,
March 2021 in “Hormones” COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.
9 citations
,
May 2015 in “Cardiology Clinics” The conclusion is that managing cholesterol is important for women, especially during pregnancy, breastfeeding, and with PCOS, and involves regular screening and careful treatment choices.
9 citations
,
June 2014 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” Blood AMH levels are higher in women with PCOS than in those with other similar conditions.
9 citations
,
December 2013 in “International journal of gynaecology and obstetrics” Polycystic ovary syndrome (PCOS) is a major health issue for women in Egypt, affecting 14% of fertile women and 37.5% of infertile women.
9 citations
,
October 2012 in “Frontiers of Hormone Research” Antiandrogens are the main treatment for hirsutism, with individualized care and safe, affordable options needed.
8 citations
,
July 2012 in “Cambridge University Press eBooks” Androgens can both increase body hair and cause scalp hair loss.
7 citations
,
January 2025 in “Archives of Gynecology and Obstetrics” Differentiating PCOS from NCAH helps improve diagnosis and treatment.