52 citations
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February 2006 in “Current pharmaceutical design” 5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.
47 citations
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August 2000 in “Endocrine Reviews” The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.
47 citations
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May 1995 in “Journal of Investigative Dermatology” Hair follicles in people with alopecia have lower levels of a key blood vessel growth protein.
36 citations
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November 1961 in “Archives of Dermatology” The document suggests that the traditional understanding of hair growth cycles and alopecia may be inaccurate and that blood supply plays a significant role in hair growth and loss.
23 citations
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January 2021 in “Biomedicine & Pharmacotherapy” DHT stops hair regrowth in mice, similar to human hair loss.
18 citations
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July 2016 in “Medicine” Wnt/β-catenin and TGF-β pathways affect hair loss, and activating Wnt/β-catenin could be a potential treatment.
18 citations
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March 2011 in “Archives of ophthalmology” Ringworm around the eyes often gets misdiagnosed, leading to eyelash loss, but antifungal treatment can improve the condition.
17 citations
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December 2018 in “The World Journal of Men s Health” Long-term use of dutasteride can cause permanent erectile dysfunction in rats.
13 citations
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April 1994 in “Journal of Investigative Dermatology” Androgen receptors found in monkey scalps, similar to humans, affect hair growth.
9 citations
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July 2011 in “Cytokine” Finasteride helps reduce lung inflammation and damage after trauma and infection.
3 citations
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September 2024 in “BMC Oral Health” Low-level laser therapy reduces orthodontic relapse in rats, but fulvic acids do not.
97 citations
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April 2016 in “Andrology” Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.
8 citations
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May 2017 in “Current traditional medicine” Stinging nettle has compounds that help with joint pain, arthritis, and prostate issues.
June 2023 in “Sains Malaysiana” Cinchonine Nanostructured Lipid Carriers serum safely and effectively stimulates hair growth and increases the number and size of hair follicles.
54 citations
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April 2019 in “Journal of cellular physiology” miR-218-5p helps skin and hair growth by targeting SFRP2 and activating a specific signaling pathway.
143 citations
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April 2018 in “Electronic physician” More research is needed to confirm safflower's traditional medicinal uses.
128 citations
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August 2015 in “Cell Stem Cell” Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.
69 citations
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January 2020 in “Veterinary World” Ringworm in pets is influenced by fungi type, immune status, and stress hormones.
68 citations
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November 2012 in “Journal of Investigative Dermatology” Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.
49 citations
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January 1998 in “International Journal of Molecular Medicine” Lipid peroxides can cause early hair loss by damaging hair follicles.
47 citations
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June 2019 in “Nature Communications” Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.
33 citations
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May 1991 in “British Journal of Pharmacology” Cromakalim relaxes various blood vessels, while minoxidil sulphate is more selective; they likely act on different potassium channels.
31 citations
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January 2017 in “Advances in Experimental Medicine and Biology” Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
27 citations
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August 1984 in “Experimental and Molecular Pathology”
26 citations
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May 2015 in “Lasers in Surgery and Medicine” Laser treatment helped regrow hair in mice by activating a key growth pathway.
23 citations
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December 2013 in “Regenerative Medicine” Hair follicle culture helps develop new treatments for hair loss.
22 citations
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March 2018 in “International Ophthalmology” Taking tamsulosin or finasteride and being older increase the risk of floppy iris during cataract surgery.
16 citations
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May 2019 in “International Journal of Women's Dermatology” The new FDA labeling rules provide more detailed drug safety information for pregnant and breastfeeding women, but more data is needed on the risks of many dermatologic drugs.
16 citations
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January 2016 in “Journal of Investigative Dermatology” Mice without the IL-6 gene had more hair growth after injury due to higher activity of a related protein, Stat3.
14 citations
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April 2017 in “American Journal of Transplantation” Skin problems from transplant drugs are common and need careful management in organ transplant patients.