19 citations
,
January 2015 in “Development” Hoxc8 gene helps start mammary gland development by controlling specific signals.
17 citations
,
October 2005 in “Journal of Biological Chemistry” Early involution in Hirosaki hairless rats' mammary glands is linked to a unique modification of STAT5A.
12 citations
,
February 2011 in “Equine veterinary education” A mare had severe symptoms and died from a large lymphoma.
8 citations
,
November 2013 in “PLOS ONE” Cells with active Wnt signaling are less likely to turn into cancer when exposed to a cancer-causing gene.
8 citations
,
January 2013 in “genesis” Zfp157 is active in many mouse tissues during development and in specific adult cells.
1 citations
,
August 2024 in “Journal of Morphology” Mammary glands evolved from hair organs in Monodelphis domestica.
1 citations
,
January 1998 in “International journal of cancer” Rubbing vitamin D3 on skin can help prevent hair loss from chemotherapy and slow breast tumor growth in mice.
November 2023 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” SLICK cattle have better heat tolerance due to specific gene expression and pathway differences.
February 2017 in “Developmental Cell” Mammary stem cells drive mammary gland growth by branching and cell mixing.
14 citations
,
January 1998 in “Dermatology” Polythelia pilosa is a type of extra breast tissue with hair and should be classified as such.
3 citations
,
April 2014 in “Anatomy Research International” Buffalo mammary glands develop in stages from 34 to 229 days during prenatal growth.
143 citations
,
May 2002 in “PubMed” LGD1069 effectively prevents breast tumors in mice without toxicity.
21 citations
,
January 2015 in “The Journal of Steroid Biochemistry and Molecular Biology” Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.
15 citations
,
May 2023 in “npj Regenerative Medicine” Macrophages help maintain mammary stem cells and tissue balance through specific signaling pathways.
3 citations
,
October 2009 in “Dermatology”
September 2025 in “American Journal of Dermatopathology” PRAME is often present in Paget disease and could help in diagnosis, but more research is needed.
September 2022 in “Research Square (Research Square)” Macrophages help maintain mammary stem cells and balance through specific signaling.
7 citations
,
January 1995 in “The Indian Journal of Animal Sciences” The Indian buffalo teat has a melanin-rich epidermis, no hair follicles, and a complex structure with muscle, blood vessels, and immune cells.
January 2024 in “ACTA SCIENTIAE VETERINARIAE” An epidermoid cyst in a dog's mammary gland is rare and benign.
218 citations
,
October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.
102 citations
,
July 2007 in “Genes & Development” A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.
36 citations
,
July 1980 in “Journal of Toxicology and Environmental Health” High doses of ethynylestradiol in rats caused growth issues, organ changes, and some tumors, but didn't increase overall tumor rates.
4 citations
,
January 1991 in “PubMed” Different bovine tissues show varying types of cytokeratins.
3 citations
,
April 2023 in “Frontiers in Pharmacology” ATP-sensitive K+ channel subunits, particularly Sur2A, play a significant role in various cancers.
Lack of certain cells causes abnormal nipple development and nursing failure.
January 1990 in “UCL Discovery (University College London)” The guinea pig α-lactalbumin gene was successfully expressed in the mammary glands of transgenic mice.
1 citations
,
January 2008 in “China Journal of Bioinformatics” Goat skin has more keratin genes, while the mammary gland has more immunity-related genes.
September 2007 in “MacSphere (McMaster University)” New biomarkers and targets for breast cancer treatment were identified to help prevent relapse and metastasis.
February 2026 in “Journal of Chittagong Medical College Teachers Association” BIMA grafting can be safely done in females with careful preparation.
89 citations
,
August 2013 in “PloS one” Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.