research Sic Transit Gloria: Farewell to the Epidermal Transit Amplifying Cell?
New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
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research Local circadian clock gates cell cycle progression of transient amplifying cells during regenerative hair cycling
Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.
research Neurogenic Inflammation in Stress-Induced Termination of Murine Hair Growth Is Promoted by Nerve Growth Factor
Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.
research Whole-genome sequencing of eight goat populations for the detection of selection signatures underlying production and adaptive traits
Researchers identified genes linked to coat color, body size, cashmere production, and high altitude adaptation in goats.
research Obesity and polycystic ovary syndrome
Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.
research A replication study confirmed the EDAR gene to be a major contributor to population differentiation regarding head hair thickness in Asia
The EDAR gene greatly affects hair thickness in Asian populations.
research Prostaglandin D2 Inhibits Wound-Induced Hair Follicle Neogenesis through the Receptor, Gpr44
Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.
research Neuronal plasticity of the “brain–skin connection”: stress-triggered up-regulation of neuropeptides in dorsal root ganglia and skin via nerve growth factor-dependent pathways
Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.
research A locus on distal chromosome 10 (ahl4) affecting age-related hearing loss in A/J mice
Scientists found a gene in mice that causes early hearing loss.
research Regulatory roles of androgens in cutaneous wound healing
Testosterone may slow down wound healing and increase inflammation.
research Improvement of endothelial function with metformin and rosiglitazone treatment in women with polycystic ovary syndrome
Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.
research Defining Hair Follicles in the Age of Stem Cell Bioengineering
The study found that bioengineered hair follicles work when using cells from the same species but have issues when combining human and mouse cells.
research Different gene expression profile observed in dermal papilla cells related to androgenic alopecia by DNA macroarray analysis
Hair loss in balding individuals is linked to changes in specific hair growth-related genes.
research Lymphatic vessels interact dynamically with the hair follicle stem cell niche during skin regeneration in vivo
Lymphatic vessels are essential for hair follicle growth and skin regeneration.
research Repurposing of Drugs as Novel Influenza Inhibitors From Clinical Gene Expression Infection Signatures
A blood pressure drug, diltiazem, may also help treat influenza.
research Measuring changes in chemistry, composition, and molecular structure within hair fibers by infrared and Raman spectroscopic imaging
Infrared and Raman imaging can non-destructively analyze hair structure and help diagnose hair conditions.
research Combination of herbal extracts and platelet-rich plasma induced dermal papilla cell proliferation: involvement of ERK and Akt pathways
Herbal extracts and platelet-rich plasma together may help increase hair growth by making certain cells grow more, through specific cell growth pathways.
research The transcriptional landscape of seasonal coat colour moult in the snowshoe hare
Researchers found genes that control hair color and growth change before the visible coat color changes in snowshoe hares.
research Micro-segmental hair analysis: detailed procedures and applications in forensic toxicology
Micro-segmental hair analysis helps detect drug use patterns and estimate drug consumption days.
research Comparative transcriptomic analysis of dermal wound healing reveals de novo skeletal muscle regeneration in Acomys cahirinus
The African spiny mouse can fully regenerate its muscle without scarring, unlike the common house mouse.
research Analysis of Dermal Papilla Cell Interactome Using STRING Database to Profile the ex Vivo Hair Growth Inhibition Effect of a Vinca Alkaloid Drug, Colchicine
Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.
research Integrative analysis of rare copy number variants and gene expression data in alopecia areata implicates an aetiological role for autophagy
The research suggests that autophagy-related genes might play a role in causing alopecia areata.
research Defining hyperandrogenaemia according to the free androgen index in Chinese women: a cross-sectional study
FAI values above 6.4 may suggest high androgen levels and increased metabolic risks in Chinese women of reproductive age.
research Identification of ultraviolet B radiation-induced microRNAs in normal human dermal papilla cells
UVB radiation changes the levels of certain microRNAs in skin cells, which may affect cell survival and hair growth.
research The inconsistent regulation of HOXC13 on different keratins and the regulation mechanism on HOXC13 in cashmere goat (Capra hircus)
The HOXC13 gene affects different hair proteins in cashmere goats in varied ways and is controlled by a feedback loop and other factors.
research Ephrin-A3 not only increases the density of hair follicles but also accelerates anagen development in neonatal mice
Ephrin-A3 helps increase and speed up hair growth in baby mice.
research Use of Nape and Peri-Auricular Hair by Follicular Unit Extraction to Create Soft Hairlines and Temples: My Experience With 128 Patients
Transplanting hair from the nape and around the ear to the hairline and temples generally satisfies patients and looks natural.
research Mouse Hair Cycle Expression Dynamics Modeled as Coupled Mesenchymal and Epithelial Oscillators
The study concluded that hair growth in mice is regulated by a stable interaction between skin cell types, and disrupting this can cause hair loss.
research The melanocyte photosensory system in the human skin
Human skin's melanocytes respond to light by changing shape, producing pigments and hormones, which may affect sleep patterns.
research Differential Expression of Proteins Associated with the Hair Follicle Cycle - Proteomics and Bioinformatics Analyses
Researchers found 44 proteins that change during different hair growth stages and may be important for hair follicle function.