research Cooperation of TGF ‐β and FGF signalling pathways in skin development
TGF-β and FGF pathways are crucial for skin development and regeneration.
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research Construction of the coexpression network involved in the pathogenesis of thyroid eye disease via bioinformatics analysis
Key genes and pathways involved in thyroid eye disease were identified, aiding potential treatment and diagnosis.
research Suppression of Cutibacterium acnes-Mediated Inflammatory Reactions by Fibroblast Growth Factor 21 in Skin
FGF21 can help reduce skin inflammation caused by C. acnes.
research Chitosan stimulates root hair callose deposition, endomembrane dynamics, and inhibits root hair growth
Chitosan affects root hair growth and callose deposition based on its concentration.
research Anti-inflammatory effects on murine macrophages of ethanol extracts of Lygodium japonicum spores via inhibition of NF-κB and p38
Lygodium japonicum spores can reduce inflammation by blocking certain cell signals.
research Cordyceps militaris Grown on Germinated Rhynchosia nulubilis (GRC) Encapsulated in Chitosan Nanoparticle (GCN) Suppresses Particulate Matter (PM)-Induced Lung Inflammation in Mice
GCN reduces lung inflammation and damage from air pollution in mice.
research Plant‐Derived Monomers for Grey Hair Reversal Through Upregulation of Melanogenesis and Tyrosinase Activity
Plant-derived compounds may help reverse grey hair by boosting melanin production.
research PSAT1 regulates hair follicle growth and stem cell behavior in cashmere goats
PSAT1 is key for hair growth and stem cell function in cashmere goats.
research Anticancer Effects of Cepharanthine: an Updated Minireview
Cepharanthine (CEP) is a bisbenzylisoquinoline alkaloid with significant anticancer properties, as highlighted in this review. It induces cancer cell death through intrinsic mitochondrial pathways, extrinsic death receptor signaling, and endoplasmic reticulum stress. CEP also halts cell proliferation by causing cell cycle arrest at G0/G1 and G2/M phases and inhibits tumor progression by suppressing metastasis, invasion, and angiogenesis. It modulates key oncogenic signaling pathways, including PI3K/Akt/mTOR, NF-B, JAK2/STAT3, and MAPK, and regulates oxidative stress in cancer cells. Additionally, CEP can reverse multidrug resistance by inhibiting drug efflux transporters, enhancing the effectiveness of conventional chemotherapies. This review underscores CEP's potential as a promising natural compound for further cancer therapy research.
research Polygonum multiflorum in AGA: network to dynamics
Polygonum multiflorum, especially emodin, may help treat hair loss by targeting specific proteins, offering a new approach beyond traditional therapies.