402 citations
,
August 2011 in “Cancer research” Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.
282 citations
,
October 2006 in “The Journal of Clinical Endocrinology and Metabolism” The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.
206 citations
,
September 2010 in “PLoS ONE” The PIRL laser cuts tissue with less damage and scarring than traditional methods.
184 citations
,
August 1983 in “The journal of pediatrics/The Journal of pediatrics” Biotinidase deficiency has various symptoms and can be treated with biotin supplements.
78 citations
,
December 2011 in “Clinical toxicology” Excessive selenium from a supplement caused toxicity but patients recovered with care.
73 citations
,
July 2016 in “Cosmetics” Mushrooms have beneficial properties for skin and hair care products and have great potential for future cosmetic use.
59 citations
,
November 2015 in “International Journal of Cosmetic Science” Oxidative stress damages hair and contributes to aging, and managing it can help maintain hair health.
54 citations
,
May 2017 in “Biomedicine & Pharmacotherapy” Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.
46 citations
,
January 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.
43 citations
,
October 2019 in “Pediatric Research” Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.
42 citations
,
March 2014 in “European Journal of Pharmacology” Ginsenoside F2 from ginseng may increase hair growth better than standard treatments by affecting cell growth signals.
30 citations
,
June 2012 in “Current Opinion in Endocrinology, Diabetes and Obesity” Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.
29 citations
,
December 2012 in “Current Opinion in Endocrinology, Diabetes and Obesity” With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.
26 citations
,
August 2014 in “PubMed” Testosterone improves mood and thinking skills; finasteride has no effect.
25 citations
,
February 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking SCD1 in the skin with XEN103 shrinks sebaceous glands in mice.
19 citations
,
January 2015 in “Current problems in dermatology” Ultraviolet rays damage hair, smoking may cause hair loss, and good nutrition is important for hair health, but genetics mainly decide hair thickness.
18 citations
,
December 2010 in “Journal of Trace Elements in Medicine and Biology” Women with AGA have more androstenedione and dihydrotestosterone, less copper and zinc; copper imbalance affects AGA; treatment improves hormones and minerals.
17 citations
,
April 2021 in “Molecules/Molecules online/Molecules annual” Linoleic acid from Malva verticillata seeds may help treat hair loss by promoting hair cell growth and blocking baldness signals.
16 citations
,
April 2012 in “Journal of mammalogy” Young female Australian fur seals are losing hair due to low tyrosine and zinc levels and high pollution exposure.
16 citations
,
September 2008 in “Dermatologic Therapy” CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.
15 citations
,
November 2017 in “Drug Delivery and Translational Research” Certain extracts from Curcuma aeruginosa Roxb. and germacrone can boost the skin's absorption of minoxidil, a hair growth promoter, making it more effective.
15 citations
,
July 2015 in “Journal of Essential Oil Bearing Plants” Thuja orientalis and Thuja occidentalis essential oils have medicinal properties useful for developing treatments with antimicrobial and bioactive effects.
14 citations
,
January 2025 in “AAPS PharmSciTech” Microemulsions and nanoemulsions can effectively deliver drugs through the skin, but more research is needed to understand their differences and mechanisms.
11 citations
,
February 2018 in “Amino acids” Copper and iron cause keratin damage in hair by converting methionine to homocysteine.
10 citations
,
February 2008 in “International Journal of Andrology” A combination of nanomilled oral testosterone and dutasteride normalized testosterone levels in men with low testosterone and is safe for short-term use.
8 citations
,
November 2022 in “International Journal of Cosmetic Science” Human hair varies widely and should be classified by curl type rather than race.
8 citations
,
October 2020 in “Infant behavior & development” Collecting hair for cortisol analysis is possible in low-income mother-toddler pairs.
8 citations
,
January 2020 in “Skin Pharmacology and Physiology” Caffeine improves hair growth, thickness, and reduces shedding.
8 citations
,
January 2016 in “Annals of Dermatology” A complex of 5-aminolevulinic acid and glycyl-histidyl-lysine peptide may help increase hair count in male pattern hair loss without side effects.
7 citations
,
September 2024 in “Applied Microbiology and Biotechnology” Malassezia furfur lipids improve skin health at pH 6.