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December 2018 in “Frontiers in Endocrinology” Differences in androgen receptor expression and tissue properties may lead to higher cryptorchidism risk in certain rats.
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August 2023 in “Biophysical Journal” Mitochondrial activity varies in cells before they stop growing, affecting their growth potential.
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September 2023 in “International journal of molecular sciences” Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.
June 2026 in “Nature Communications” The study examines how dermal fibroblasts respond to mechanical stretching and influence epidermal stem cell behavior during skin expansion, using a mouse model with 32 subjects. It was found that stretching induces a fibroblast program characterized by reduced collagen deposition and increased proliferation, promoting epidermal stem cell self-renewal. Single-cell RNA sequencing revealed transcriptional changes in fibroblasts, particularly in the upper dermis, with upregulation of genes associated with extracellular matrix remodeling and an embryonic-like regenerative state. The research highlights the dynamic interaction between fibroblasts and keratinocytes, suggesting that fibroblasts play a crucial role in skin expansion by rapidly altering their transcriptional landscape, which has implications for understanding skin regeneration and repair mechanisms.
Chirality influences the structure, strength, and biological uses of peptide-based hydrogels.
January 2026 in “Materialia” Porcine ADM scaffold helps hair growth in mice.
December 2025 in “The Journal of Cell Biology” Keratin 15 helps maintain skin cell growth and repair.
November 2025 in “Preprints.org” New-onset fibromyalgia after COVID-19 is poorly understood and needs more research.
August 2024 in “Nature Communications” Softer hydrogels help wounds heal better with less scarring.
August 2024 in “Stem Cell Research & Therapy” New regenerative therapies show promise for treating hair loss.
Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.
August 2023 in “Stem cell reviews and reports”
Sensory neuron remodeling and Merkel-cell changes happen independently during skin maintenance.
Sensory neuron changes and Merkel-cell changes in the skin happen independently during normal skin maintenance.
Sensory neuron and Merkel cell changes in the skin happen independently during normal skin maintenance.
Sensory neurons and Merkel cells remodel at different rates during normal skin maintenance.
Sensory neuron remodeling and Merkel-cell changes in the skin happen independently.
Sensory neuron and Merkel-cell changes in the skin happen independently during normal skin maintenance.
Sensory neuron and Merkel cell changes in the skin happen independently during normal skin maintenance.
April 2018 in “Journal of Investigative Dermatology” Lymphocytes, a type of immune cell, are crucial for wound healing as they help remodel damaged areas and reduce inflammation.
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December 2011 in “Cell” Different hair follicles in the skin are innervated by unique combinations of mechanosensory neurons, crucial for touch sensation.
The transcription factor Meis2 is essential for touch sensation and proper nerve development in touch receptors.
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August 2023 in “Developmental Cell” Mechanosensory neurons adapt to different skin types after birth.
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December 2009 in “Journal of the Peripheral Nervous System” TRPA1 and TRPV1 channels don't affect mechanotransduction in rat sinus hair follicles.